ID A7SPY2_NEMVE Unreviewed; 270 AA.
AC A7SPY2;
DT 02-OCT-2007, integrated into UniProtKB/TrEMBL.
DT 02-OCT-2007, sequence version 1.
DT 27-MAR-2024, entry version 64.
DE RecName: Full=Sulfatase N-terminal domain-containing protein {ECO:0000259|Pfam:PF00884};
GN ORFNames=NEMVEDRAFT_v1g126527 {ECO:0000313|EMBL:EDO34252.1};
OS Nematostella vectensis (Starlet sea anemone).
OC Eukaryota; Metazoa; Cnidaria; Anthozoa; Hexacorallia; Actiniaria;
OC Edwardsiidae; Nematostella.
OX NCBI_TaxID=45351 {ECO:0000313|EMBL:EDO34252.1, ECO:0000313|Proteomes:UP000001593};
RN [1] {ECO:0000313|EMBL:EDO34252.1, ECO:0000313|Proteomes:UP000001593}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CH2 X CH6 {ECO:0000313|Proteomes:UP000001593};
RX PubMed=17615350; DOI=10.1126/science.1139158;
RA Putnam N.H., Srivastava M., Hellsten U., Dirks B., Chapman J., Salamov A.,
RA Terry A., Shapiro H., Lindquist E., Kapitonov V.V., Jurka J.,
RA Genikhovich G., Grigoriev I.V., Lucas S.M., Steele R.E., Finnerty J.R.,
RA Technau U., Martindale M.Q., Rokhsar D.S.;
RT "Sea anemone genome reveals ancestral eumetazoan gene repertoire and
RT genomic organization.";
RL Science 317:86-94(2007).
CC -!- COFACTOR:
CC Name=Ca(2+); Xref=ChEBI:CHEBI:29108;
CC Evidence={ECO:0000256|ARBA:ARBA00001913};
CC -!- SIMILARITY: Belongs to the sulfatase family.
CC {ECO:0000256|ARBA:ARBA00008779}.
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DR EMBL; DS469738; EDO34252.1; -; Genomic_DNA.
DR RefSeq; XP_001626352.1; XM_001626302.1.
DR AlphaFoldDB; A7SPY2; -.
DR STRING; 45351.A7SPY2; -.
DR EnsemblMetazoa; EDO34252; EDO34252; NEMVEDRAFT_v1g126527.
DR eggNOG; KOG3867; Eukaryota.
DR HOGENOM; CLU_006332_3_0_1; -.
DR InParanoid; A7SPY2; -.
DR OMA; DHTHYML; -.
DR PhylomeDB; A7SPY2; -.
DR Proteomes; UP000001593; Unassembled WGS sequence.
DR GO; GO:0008484; F:sulfuric ester hydrolase activity; IEA:UniProt.
DR CDD; cd16029; 4-S; 1.
DR Gene3D; 3.40.720.10; Alkaline Phosphatase, subunit A; 1.
DR InterPro; IPR017850; Alkaline_phosphatase_core_sf.
DR InterPro; IPR047115; ARSB.
DR InterPro; IPR024607; Sulfatase_CS.
DR InterPro; IPR000917; Sulfatase_N.
DR PANTHER; PTHR10342; ARYLSULFATASE; 1.
DR PANTHER; PTHR10342:SF273; RE14504P; 1.
DR Pfam; PF00884; Sulfatase; 1.
DR SUPFAM; SSF53649; Alkaline phosphatase-like; 1.
DR PROSITE; PS00523; SULFATASE_1; 1.
DR PROSITE; PS00149; SULFATASE_2; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Reference proteome {ECO:0000313|Proteomes:UP000001593}.
FT DOMAIN 3..264
FT /note="Sulfatase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00884"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:EDO34252.1"
SQ SEQUENCE 270 AA; 30280 MW; 084050446756870D CRC64;
KKPNIVMIVA DDLGWDDVSF HGSSQIPTPT IDKLASEGVI LNSYYVSPIC TPTRASLMTG
KHPMNLGMLI HTHATVFGTQ PYGLPLGETT TPQYMKSLGY VTHGIGKWHL GFFEKEYTPT
YRGFDSFYGF WNGKEDYWDH SSQEDVWGTD LRDNEKPVRN ESGHYGTELF AERAAQIIHL
HNQTKPLYLY LAQQGVHSAN GNEPLQAPKR LIKKFSHISS PKRRIYAAMV SSLDESVETV
HKALSETGML NNTVLVFTTD NGGAPRGFNW
//
