ID A7SVV4_NEMVE Unreviewed; 486 AA.
AC A7SVV4;
DT 02-OCT-2007, integrated into UniProtKB/TrEMBL.
DT 02-OCT-2007, sequence version 1.
DT 24-JAN-2024, entry version 59.
DE RecName: Full=Potassium channel domain-containing protein {ECO:0000259|Pfam:PF07885};
GN ORFNames=NEMVEDRAFT_v1g247709 {ECO:0000313|EMBL:EDO32177.1};
OS Nematostella vectensis (Starlet sea anemone).
OC Eukaryota; Metazoa; Cnidaria; Anthozoa; Hexacorallia; Actiniaria;
OC Edwardsiidae; Nematostella.
OX NCBI_TaxID=45351 {ECO:0000313|EMBL:EDO32177.1, ECO:0000313|Proteomes:UP000001593};
RN [1] {ECO:0000313|EMBL:EDO32177.1, ECO:0000313|Proteomes:UP000001593}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CH2 X CH6 {ECO:0000313|Proteomes:UP000001593};
RX PubMed=17615350; DOI=10.1126/science.1139158;
RA Putnam N.H., Srivastava M., Hellsten U., Dirks B., Chapman J., Salamov A.,
RA Terry A., Shapiro H., Lindquist E., Kapitonov V.V., Jurka J.,
RA Genikhovich G., Grigoriev I.V., Lucas S.M., Steele R.E., Finnerty J.R.,
RA Technau U., Martindale M.Q., Rokhsar D.S.;
RT "Sea anemone genome reveals ancestral eumetazoan gene repertoire and
RT genomic organization.";
RL Science 317:86-94(2007).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; DS469845; EDO32177.1; -; Genomic_DNA.
DR RefSeq; XP_001624277.1; XM_001624227.1.
DR AlphaFoldDB; A7SVV4; -.
DR STRING; 45351.A7SVV4; -.
DR EnsemblMetazoa; EDO32177; EDO32177; NEMVEDRAFT_v1g247709.
DR eggNOG; KOG1545; Eukaryota.
DR HOGENOM; CLU_037255_0_0_1; -.
DR InParanoid; A7SVV4; -.
DR PhylomeDB; A7SVV4; -.
DR Proteomes; UP000001593; Unassembled WGS sequence.
DR GO; GO:0008076; C:voltage-gated potassium channel complex; IBA:GO_Central.
DR GO; GO:0005251; F:delayed rectifier potassium channel activity; IBA:GO_Central.
DR GO; GO:0071805; P:potassium ion transmembrane transport; IBA:GO_Central.
DR Gene3D; 1.10.287.70; -; 1.
DR Gene3D; 3.40.190.10; Periplasmic binding protein-like II; 1.
DR InterPro; IPR013099; K_chnl_dom.
DR PANTHER; PTHR11537:SF252; POTASSIUM VOLTAGE-GATED CHANNEL PROTEIN SHAW; 1.
DR PANTHER; PTHR11537; VOLTAGE-GATED POTASSIUM CHANNEL; 1.
DR Pfam; PF07885; Ion_trans_2; 1.
DR PRINTS; PR00169; KCHANNEL.
DR SUPFAM; SSF53850; Periplasmic binding protein-like II; 1.
DR SUPFAM; SSF81324; Voltage-gated potassium channels; 1.
PE 4: Predicted;
KW Ion channel {ECO:0000256|ARBA:ARBA00023303};
KW Ion transport {ECO:0000256|ARBA:ARBA00023065};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000001593};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 12..33
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 214..239
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 387..409
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 186..239
FT /note="Potassium channel"
FT /evidence="ECO:0000259|Pfam:PF07885"
SQ SEQUENCE 486 AA; 55349 MW; 58D24DBAE205EEEB CRC64;
MLKVNTIKTG LWWILLICAF GSQFTDATIS IIASSDTSNL STKFNSYRNA TNLTLQERCK
QGLPLSIAVY PYPPYVRVKP GAELNNGLRR YTLTGMIPEL LSSLLNSCCH PNTKVEFGTV
LPSLRAAENI LFDKFFDVVF PIYGYDVIEY AFRGHVFVRL FQAPSVVLLE HTSNSKEFPP
SFFEGTWEGF WWALVTMTTV GYGDRTPKSR FGRVFAMLWI LTGVTTISIF TALVTSSLWA
STTPNFRLHG SVIGAINGSE EYRLAVNLNA EVKAFSKVEP MLNNLSNHVI DGAMIDNYVI
TEHLEMLTAG HMRTEETMYY PITYGMTMSR DSGDFENCVN WMLHNYPGTR HQATARNLKP
LKNPADKVSA QFRAAEGLFF KEKTFEIVTY SGMAVVGVFI LTGVVWEYFW RRPKLTKHLA
PPEIDEKPRY SKDDSDAQML DSGIQRRQEL KRMISKYRAY QEEWIRGVQE VCDERAIRNT
SELMNQ
//
