ID A7TZ37_LEPSM Unreviewed; 296 AA.
AC A7TZ37;
DT 02-OCT-2007, integrated into UniProtKB/TrEMBL.
DT 02-OCT-2007, sequence version 1.
DT 27-MAR-2024, entry version 34.
DE RecName: Full=Large ribosomal subunit protein uL18 {ECO:0000256|ARBA:ARBA00035197};
DE AltName: Full=60S ribosomal protein L5 {ECO:0000256|ARBA:ARBA00035352};
OS Lepeophtheirus salmonis (Salmon louse).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Crustacea; Multicrustacea;
OC Hexanauplia; Copepoda; Siphonostomatoida; Caligidae; Lepeophtheirus.
OX NCBI_TaxID=72036 {ECO:0000313|EMBL:ABU41033.1};
RN [1] {ECO:0000313|EMBL:ABU41033.1}
RP NUCLEOTIDE SEQUENCE.
RA Eichner C., Frost P., Dysvik B., Kristiansen B., Jonassen I., Nilsen F.;
RT "Salmon louse (Lepeophtheirus salmonis) transcriptomes during post molting
RT maturation and egg production, revealed using EST-sequencing and microarray
RT analysis.";
RL Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Component of the ribosome, a large ribonucleoprotein complex
CC responsible for the synthesis of proteins in the cell. The small
CC ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the
CC encoded message by selecting cognate aminoacyl-transfer RNA (tRNA)
CC molecules. The large subunit (LSU) contains the ribosomal catalytic
CC site termed the peptidyl transferase center (PTC), which catalyzes the
CC formation of peptide bonds, thereby polymerizing the amino acids
CC delivered by tRNAs into a polypeptide chain. The nascent polypeptides
CC leave the ribosome through a tunnel in the LSU and interact with
CC protein factors that function in enzymatic processing, targeting, and
CC the membrane insertion of nascent chains at the exit of the ribosomal
CC tunnel. {ECO:0000256|ARBA:ARBA00004021}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC -!- SIMILARITY: Belongs to the universal ribosomal protein uL18 family.
CC {ECO:0000256|ARBA:ARBA00007116}.
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DR EMBL; EF490848; ABU41033.1; -; mRNA.
DR GO; GO:0022626; C:cytosolic ribosome; IEA:UniProt.
DR GO; GO:1990904; C:ribonucleoprotein complex; IEA:UniProtKB-KW.
DR GO; GO:0008097; F:5S rRNA binding; IEA:InterPro.
DR GO; GO:0003735; F:structural constituent of ribosome; IEA:InterPro.
DR GO; GO:0006412; P:translation; IEA:InterPro.
DR CDD; cd00432; Ribosomal_L18_L5e; 1.
DR Gene3D; 3.30.420.100; -; 1.
DR HAMAP; MF_01337_A; Ribosomal_L18_A; 1.
DR InterPro; IPR005485; Rbsml_uL18_euk/arc.
DR InterPro; IPR025607; Ribosomal_uL18_C_euk.
DR PANTHER; PTHR23410:SF12; 60S RIBOSOMAL PROTEIN L5; 1.
DR PANTHER; PTHR23410; RIBOSOMAL PROTEIN L5-RELATED; 1.
DR Pfam; PF14204; Ribosomal_L18_c; 1.
DR Pfam; PF17144; Ribosomal_L5e; 1.
DR PRINTS; PR00058; RIBOSOMALL5.
DR SUPFAM; SSF53137; Translational machinery components; 1.
PE 2: Evidence at transcript level;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Ribonucleoprotein {ECO:0000256|ARBA:ARBA00023274};
KW Ribosomal protein {ECO:0000256|ARBA:ARBA00022980,
KW ECO:0000313|EMBL:ABU41033.1}.
FT DOMAIN 236..289
FT /note="Large ribosomal subunit protein uL18 C-terminal
FT eukaryotes"
FT /evidence="ECO:0000259|Pfam:PF14204"
SQ SEQUENCE 296 AA; 33980 MW; B49BB1D564F9A7E4 CRC64;
MVFVKVVKCK AYFKRYQVKF RRRREGRTDY YARKRLVVQD KNKYNTPKYR MIVRFTNKDI
CCQIAYARID GDRIVEAAYA HELPRYGVKV GLTNYAAAYC TGLLLARRVL NKFKLDSIYE
GQTKVDGEHF MVEDEEGKPG AFRACLDTGL ARTSTGAKVF GAMKGAADGG LDVPHSVKRF
PGYDNEENQF DAKTHRSHIF GKHVADYMEL LQQGEPEAYK RQFSQYIKHG VTPSSMEDMY
XKAHAAIRKD PTRPKKPVKK VQKKRFNAKK LTGEERKAKV KAAKAEFLAQ IEAQKE
//
