ID   A7VFQ7_9CLOT            Unreviewed;       255 AA.
AC   A7VFQ7;
DT   23-OCT-2007, integrated into UniProtKB/TrEMBL.
DT   23-OCT-2007, sequence version 1.
DT   27-MAR-2024, entry version 42.
DE   RecName: Full=DUF218 domain-containing protein {ECO:0000259|Pfam:PF02698};
GN   ORFNames=CLOL250_01754 {ECO:0000313|EMBL:EDO57664.1};
OS   Clostridium sp. L2-50.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae;
OC   Clostridium.
OX   NCBI_TaxID=411489 {ECO:0000313|EMBL:EDO57664.1, ECO:0000313|Proteomes:UP000003352};
RN   [1] {ECO:0000313|EMBL:EDO57664.1, ECO:0000313|Proteomes:UP000003352}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=L2-50 {ECO:0000313|EMBL:EDO57664.1,
RC   ECO:0000313|Proteomes:UP000003352};
RA   Sudarsanam P., Ley R., Guruge J., Turnbaugh P.J., Mahowald M., Liep D.,
RA   Gordon J.;
RT   "Draft genome sequence of Clostridium sp. L2-50.";
RL   Submitted (AUG-2007) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:EDO57664.1, ECO:0000313|Proteomes:UP000003352}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=L2-50 {ECO:0000313|EMBL:EDO57664.1,
RC   ECO:0000313|Proteomes:UP000003352};
RA   Fulton L., Clifton S., Fulton B., Xu J., Minx P., Pepin K.H., Johnson M.,
RA   Thiruvilangam P., Bhonagiri V., Nash W.E., Hodges J., Shah N., Mardis E.R.,
RA   Wilson R.K.;
RL   Submitted (AUG-2007) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EDO57664.1}.
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DR   EMBL; AAYW02000014; EDO57664.1; -; Genomic_DNA.
DR   AlphaFoldDB; A7VFQ7; -.
DR   eggNOG; COG1434; Bacteria.
DR   HOGENOM; CLU_051474_2_2_9; -.
DR   OrthoDB; 9782395at2; -.
DR   Proteomes; UP000003352; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   CDD; cd06259; YdcF-like; 1.
DR   Gene3D; 3.40.50.620; HUPs; 1.
DR   InterPro; IPR003848; DUF218.
DR   InterPro; IPR014729; Rossmann-like_a/b/a_fold.
DR   PANTHER; PTHR30336; INNER MEMBRANE PROTEIN, PROBABLE PERMEASE; 1.
DR   PANTHER; PTHR30336:SF6; INTEGRAL MEMBRANE PROTEIN-RELATED; 1.
DR   Pfam; PF02698; DUF218; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        6..26
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        33..53
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        73..94
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          106..247
FT                   /note="DUF218"
FT                   /evidence="ECO:0000259|Pfam:PF02698"
SQ   SEQUENCE   255 AA;  28792 MW;  F90BEDBF8AE717F8 CRC64;
     MKKLWLRIVL FIAGFAGVFI FLYPFVTKGI KNIGNLTGVV LGICLILYAA WFHRVNCRVK
     KWLTRTTGKV ICGIVLLIVL VAVGFAAAGT ICMVRASKTA PKDETVMIVL GCGVNGDRPS
     LMLTERLDAA YDYLNTHEEV VGILSGGQGK GENISEAECM YRYLTEKGIA KERLYKEERS
     TSTRENLLYS KKIMEEEHLD FRVIIVTNEF HEYRASVIAE HTGITPSAVC GKTAWWLLPT
     YYLRELYGIV FEWIF
//