ID A7VHG6_9CLOT Unreviewed; 275 AA.
AC A7VHG6;
DT 23-OCT-2007, integrated into UniProtKB/TrEMBL.
DT 23-OCT-2007, sequence version 1.
DT 24-JAN-2024, entry version 48.
DE RecName: Full=UDP-N-acetylglucosamine kinase {ECO:0000256|ARBA:ARBA00011963};
DE EC=2.7.1.176 {ECO:0000256|ARBA:ARBA00011963};
DE AltName: Full=UDP-N-acetylglucosamine kinase {ECO:0000256|ARBA:ARBA00032897};
GN ORFNames=CLOL250_02363 {ECO:0000313|EMBL:EDO56675.1};
OS Clostridium sp. L2-50.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae;
OC Clostridium.
OX NCBI_TaxID=411489 {ECO:0000313|EMBL:EDO56675.1, ECO:0000313|Proteomes:UP000003352};
RN [1] {ECO:0000313|EMBL:EDO56675.1, ECO:0000313|Proteomes:UP000003352}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=L2-50 {ECO:0000313|EMBL:EDO56675.1,
RC ECO:0000313|Proteomes:UP000003352};
RA Sudarsanam P., Ley R., Guruge J., Turnbaugh P.J., Mahowald M., Liep D.,
RA Gordon J.;
RT "Draft genome sequence of Clostridium sp. L2-50.";
RL Submitted (AUG-2007) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:EDO56675.1, ECO:0000313|Proteomes:UP000003352}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=L2-50 {ECO:0000313|EMBL:EDO56675.1,
RC ECO:0000313|Proteomes:UP000003352};
RA Fulton L., Clifton S., Fulton B., Xu J., Minx P., Pepin K.H., Johnson M.,
RA Thiruvilangam P., Bhonagiri V., Nash W.E., Hodges J., Shah N., Mardis E.R.,
RA Wilson R.K.;
RL Submitted (AUG-2007) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + UDP-N-acetyl-alpha-D-glucosamine = ADP + H(+) + UDP-N-
CC acetyl-alpha-D-glucosamine 3'-phosphate; Xref=Rhea:RHEA:32671,
CC ChEBI:CHEBI:15378, ChEBI:CHEBI:30616, ChEBI:CHEBI:57705,
CC ChEBI:CHEBI:64353, ChEBI:CHEBI:456216; EC=2.7.1.176;
CC Evidence={ECO:0000256|ARBA:ARBA00000912};
CC -!- SIMILARITY: Belongs to the zeta toxin family.
CC {ECO:0000256|ARBA:ARBA00009104}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EDO56675.1}.
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DR EMBL; AAYW02000018; EDO56675.1; -; Genomic_DNA.
DR RefSeq; WP_008399817.1; NZ_DS480312.1.
DR AlphaFoldDB; A7VHG6; -.
DR eggNOG; COG0683; Bacteria.
DR HOGENOM; CLU_905478_0_0_9; -.
DR OrthoDB; 1837979at2; -.
DR Proteomes; UP000003352; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016301; F:kinase activity; IEA:InterPro.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR010488; Zeta_toxin_domain.
DR Pfam; PF06414; Zeta_toxin; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741}.
FT DOMAIN 29..88
FT /note="Zeta toxin"
FT /evidence="ECO:0000259|Pfam:PF06414"
SQ SEQUENCE 275 AA; 31805 MW; 3C21FF00A9ACB6EA CRC64;
MDTKEITVSD LAQEQIKNAE RLFPLIRKKT EERKEKKTVI SVSGGSGVGK TGMAFLLQNM
FEKQGKKSLI ISGDNYPHRI PMYNDAERIA RFRMSGLNGL ITERLYTDEI KEKLLKLQKA
GRDAEEQEDM QWLSIYQKYG DKALTDYLGT DQELDYEAIS NLLMQFHRGT SQLLLRHMGR
TQDDIWYDRR DVSDTDILIL EWTHGNSAYL QGVDVSVVLI STPEETLENR KKRNRDTAID
SPFVARVLRI EQKKINDGLD RADIIQDMHG RIYTE
//
