ID   A7WQN1_HBV              Unreviewed;       210 AA.
AC   A7WQN1;
DT   23-OCT-2007, integrated into UniProtKB/TrEMBL.
DT   23-OCT-2007, sequence version 1.
DT   14-DEC-2022, entry version 37.
DE   SubName: Full=Polymerase {ECO:0000313|EMBL:ABU83079.1};
DE   Flags: Fragment;
GN   Name=P {ECO:0000313|EMBL:ABU83079.1};
OS   Hepatitis B virus (HBV).
OC   Viruses; Riboviria; Pararnavirae; Artverviricota; Revtraviricetes;
OC   Blubervirales; Hepadnaviridae; Orthohepadnavirus.
OX   NCBI_TaxID=10407 {ECO:0000313|EMBL:ABU83079.1};
OH   NCBI_TaxID=9606; Homo sapiens (Human).
OH   NCBI_TaxID=9598; Pan troglodytes (Chimpanzee).
RN   [1] {ECO:0000313|EMBL:ABU83079.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=FR-HBVrt-pt1-8-7 {ECO:0000313|EMBL:ABU83079.1};
RX   PubMed=19065672; DOI=10.1002/hep.22634;
RA   Pallier C., Rodriguez C., Brillet R., Nordmann P., Hezode C.,
RA   Pawlotsky J.M.;
RT   "Complex dynamics of hepatitis B virus resistance to adefovir.";
RL   Hepatology 49:50-59(2009).
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; EU026581; ABU83079.1; -; Genomic_DNA.
DR   GO; GO:0003887; F:DNA-directed DNA polymerase activity; IEA:UniProtKB-KW.
DR   GO; GO:0004519; F:endonuclease activity; IEA:UniProtKB-KW.
DR   GO; GO:0003964; F:RNA-directed DNA polymerase activity; IEA:UniProtKB-KW.
DR   Gene3D; 3.30.70.270; -; 1.
DR   InterPro; IPR043502; DNA/RNA_pol_sf.
DR   InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR   InterPro; IPR000477; RT_dom.
DR   Pfam; PF00078; RVT_1; 1.
DR   SUPFAM; SSF56672; DNA/RNA polymerases; 1.
DR   PROSITE; PS50878; RT_POL; 1.
PE   4: Predicted;
KW   DNA-directed DNA polymerase {ECO:0000256|ARBA:ARBA00022932};
KW   Endonuclease {ECO:0000256|ARBA:ARBA00022759};
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Nuclease {ECO:0000256|ARBA:ARBA00022722};
KW   Nucleotidyltransferase {ECO:0000256|ARBA:ARBA00022695};
KW   RNA-directed DNA polymerase {ECO:0000256|ARBA:ARBA00022918};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT   DOMAIN          1..189
FT                   /note="Reverse transcriptase"
FT                   /evidence="ECO:0000259|PROSITE:PS50878"
FT   NON_TER         1
FT                   /evidence="ECO:0000313|EMBL:ABU83079.1"
FT   NON_TER         210
FT                   /evidence="ECO:0000313|EMBL:ABU83079.1"
SQ   SEQUENCE   210 AA;  23556 MW;  4F4B118F6408CBA6 CRC64;
     LQSLTNLLSS NLSWLSLDVS AAFYHLPLHP AAMPHLLVGS SGLSRYVARL SSDSKIFNHQ
     RGTMQNLHDC CSRNLYVSLL LLYQTFGRKL HLYSHPIILG FRKIPVGVGL SPFLLAQFTS
     AICSVVRRAF PHCLAFSYMD DVVLGAKSVQ HLESLFTAVT NFLLSLGIHL NPNKTKRWGY
     SLNFMGYVIG CYGSLPQDHI IQKIKDCFRK
//