ID   A7ZMV0_ECO24            Unreviewed;       263 AA.
AC   A7ZMV0;
DT   23-OCT-2007, integrated into UniProtKB/TrEMBL.
DT   23-OCT-2007, sequence version 1.
DT   27-MAR-2024, entry version 89.
DE   SubName: Full=Transcriptional regulator KdgR {ECO:0000313|EMBL:ABV19818.1};
GN   Name=kdgR {ECO:0000313|EMBL:ABV19818.1};
GN   OrderedLocusNames=EcE24377A_2056 {ECO:0000313|EMBL:ABV19818.1};
OS   Escherichia coli O139:H28 (strain E24377A / ETEC).
OC   Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=331111 {ECO:0000313|EMBL:ABV19818.1, ECO:0000313|Proteomes:UP000001122};
RN   [1] {ECO:0000313|Proteomes:UP000001122}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=E24377A / ETEC {ECO:0000313|Proteomes:UP000001122};
RX   PubMed=18676672; DOI=10.1128/JB.00619-08;
RA   Rasko D.A., Rosovitz M.J., Myers G.S., Mongodin E.F., Fricke W.F.,
RA   Gajer P., Crabtree J., Sebaihia M., Thomson N.R., Chaudhuri R.,
RA   Henderson I.R., Sperandio V., Ravel J.;
RT   "The pangenome structure of Escherichia coli: comparative genomic analysis
RT   of E. coli commensal and pathogenic isolates.";
RL   J. Bacteriol. 190:6881-6893(2008).
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CP000800; ABV19818.1; -; Genomic_DNA.
DR   RefSeq; WP_001262174.1; NC_009801.1.
DR   AlphaFoldDB; A7ZMV0; -.
DR   GeneID; 75202654; -.
DR   KEGG; ecw:EcE24377A_2056; -.
DR   HOGENOM; CLU_062618_6_0_6; -.
DR   Proteomes; UP000001122; Chromosome.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR   CDD; cd00090; HTH_ARSR; 1.
DR   Gene3D; 3.30.450.40; -; 1.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR   InterPro; IPR011991; ArsR-like_HTH.
DR   InterPro; IPR029016; GAF-like_dom_sf.
DR   InterPro; IPR014757; Tscrpt_reg_IclR_C.
DR   InterPro; IPR005471; Tscrpt_reg_IclR_N.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   PANTHER; PTHR30136; HELIX-TURN-HELIX TRANSCRIPTIONAL REGULATOR, ICLR FAMILY; 1.
DR   PANTHER; PTHR30136:SF7; HTH-TYPE TRANSCRIPTIONAL REGULATOR XYNR-RELATED; 1.
DR   Pfam; PF09339; HTH_IclR; 1.
DR   Pfam; PF01614; IclR; 1.
DR   SMART; SM00346; HTH_ICLR; 1.
DR   SUPFAM; SSF55781; GAF domain-like; 1.
DR   SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR   PROSITE; PS51077; HTH_ICLR; 1.
DR   PROSITE; PS51078; ICLR_ED; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000001122};
KW   Transcription {ECO:0000256|ARBA:ARBA00023163};
KW   Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT   DOMAIN          13..74
FT                   /note="HTH iclR-type"
FT                   /evidence="ECO:0000259|PROSITE:PS51077"
FT   DOMAIN          75..258
FT                   /note="IclR-ED"
FT                   /evidence="ECO:0000259|PROSITE:PS51078"
SQ   SEQUENCE   263 AA;  29986 MW;  4D2D5A57ABCDFD9C CRC64;
     MANADLDKQP DSVSSVLKVF GILQALGEER EIGITELSQR VMMSKSTVYR FLQTMKTLGY
     VAQEGESEKY SLTLKLFELG ARALQNVDLI RSADIQMREI SRLTKETIHL GALDEDSIVY
     IHKIDSMYNL RMYSRIGRRN PLYSTAIGKV LLAWRDLDEV KQILEGVEYK RSTERTITST
     EALLPVLDQV REQGYGEDNE EQEEGLRCIA VPVFDRFGVV IAGLSISFPT LRFSEERLQE
     YVAMLHTAAR KISAQMGYHD YPF
//