ID A8AJM1_CITK8 Unreviewed; 1294 AA.
AC A8AJM1;
DT 23-OCT-2007, integrated into UniProtKB/TrEMBL.
DT 23-OCT-2007, sequence version 1.
DT 27-MAR-2024, entry version 96.
DE RecName: Full=Carrier domain-containing protein {ECO:0000259|PROSITE:PS50075};
GN OrderedLocusNames=CKO_02575 {ECO:0000313|EMBL:ABV13684.1};
OS Citrobacter koseri (strain ATCC BAA-895 / CDC 4225-83 / SGSC4696).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Citrobacter.
OX NCBI_TaxID=290338 {ECO:0000313|EMBL:ABV13684.1, ECO:0000313|Proteomes:UP000008148};
RN [1] {ECO:0000313|EMBL:ABV13684.1, ECO:0000313|Proteomes:UP000008148}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-895 / CDC 4225-83 / SGSC4696
RC {ECO:0000313|Proteomes:UP000008148};
RG The Citrobacter koseri Genome Sequencing Project;
RA McClelland M., Sanderson E.K., Porwollik S., Spieth J., Clifton W.S.,
RA Latreille P., Courtney L., Wang C., Pepin K., Bhonagiri V., Nash W.,
RA Johnson M., Thiruvilangam P., Wilson R.;
RL Submitted (AUG-2007) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=pantetheine 4'-phosphate; Xref=ChEBI:CHEBI:47942;
CC Evidence={ECO:0000256|ARBA:ARBA00001957};
CC -!- PATHWAY: Siderophore biosynthesis. {ECO:0000256|ARBA:ARBA00004924}.
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DR EMBL; CP000822; ABV13684.1; -; Genomic_DNA.
DR RefSeq; WP_012133403.1; NC_009792.1.
DR STRING; 290338.CKO_02575; -.
DR GeneID; 45136446; -.
DR KEGG; cko:CKO_02575; -.
DR HOGENOM; CLU_000022_2_13_6; -.
DR OrthoDB; 9757559at2; -.
DR Proteomes; UP000008148; Chromosome.
DR GO; GO:0016874; F:ligase activity; IEA:UniProtKB-KW.
DR GO; GO:0043604; P:amide biosynthetic process; IEA:UniProt.
DR GO; GO:0019752; P:carboxylic acid metabolic process; IEA:UniProt.
DR GO; GO:1901566; P:organonitrogen compound biosynthetic process; IEA:UniProt.
DR GO; GO:0044550; P:secondary metabolite biosynthetic process; IEA:UniProt.
DR CDD; cd17646; A_NRPS_AB3403-like; 1.
DR Gene3D; 3.30.300.30; -; 1.
DR Gene3D; 3.40.50.980; -; 2.
DR Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR Gene3D; 3.30.559.10; Chloramphenicol acetyltransferase-like domain; 1.
DR Gene3D; 3.30.559.30; Nonribosomal peptide synthetase, condensation domain; 1.
DR InterPro; IPR010071; AA_adenyl_domain.
DR InterPro; IPR029058; AB_hydrolase.
DR InterPro; IPR036736; ACP-like_sf.
DR InterPro; IPR045851; AMP-bd_C_sf.
DR InterPro; IPR020845; AMP-binding_CS.
DR InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR InterPro; IPR023213; CAT-like_dom_sf.
DR InterPro; IPR001242; Condensatn.
DR InterPro; IPR020802; PKS_thioesterase.
DR InterPro; IPR009081; PP-bd_ACP.
DR InterPro; IPR006162; Ppantetheine_attach_site.
DR InterPro; IPR001031; Thioesterase.
DR NCBIfam; TIGR01733; AA-adenyl-dom; 1.
DR PANTHER; PTHR45527:SF1; FATTY ACID SYNTHASE; 1.
DR PANTHER; PTHR45527; NONRIBOSOMAL PEPTIDE SYNTHETASE; 1.
DR Pfam; PF00501; AMP-binding; 1.
DR Pfam; PF00668; Condensation; 1.
DR Pfam; PF00550; PP-binding; 1.
DR Pfam; PF00975; Thioesterase; 1.
DR SMART; SM00824; PKS_TE; 1.
DR SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 1.
DR SUPFAM; SSF47336; ACP-like; 1.
DR SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
DR SUPFAM; SSF52777; CoA-dependent acyltransferases; 2.
DR PROSITE; PS00455; AMP_BINDING; 1.
DR PROSITE; PS50075; CARRIER; 1.
DR PROSITE; PS00012; PHOSPHOPANTETHEINE; 1.
PE 4: Predicted;
KW Ligase {ECO:0000256|ARBA:ARBA00022598};
KW Phosphopantetheine {ECO:0000256|ARBA:ARBA00022450};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000008148}.
FT DOMAIN 971..1046
FT /note="Carrier"
FT /evidence="ECO:0000259|PROSITE:PS50075"
SQ SEQUENCE 1294 AA; 141882 MW; 63CB1F447A6F1B42 CRC64;
MTTRLPLVAA QPGIWMAEKL STLPSAWSVA HYVELHGTLN APLLAQAVVT GMAQADTLRM
RFTEDNGEVW QWVDPAFTFA QPELIDLRDE PDPHAAALAR MQADLRQNLR VDGGKPLAFH
QLIQVADTRW YWYQRYHHLL VDGFSFPAIT RQIAAIYRAW QCNAPTPDSP FTPFADVVEE
YQRYRESEVY QRDGAFWAEQ RRQLPPPASL SAAPLPGRAA SADILRMKLD VPDGVFRQLA
ARMSDIQRAD LALALVALWL GRLCGRMDYA AGFIFMRRMG SAALTATGPV LNVLPLGVSI
NAAETLPELA TRLAGQMKKM RRHQRYDAEQ IVRDSGRAAG EEPLFGPVLN VKVFDYQLDI
PGVQAQTHTL ATGPVNDLEL ALFPDEEGGL SIEILANKQR YDEATLSCHA SRLTALIRQF
ADNPALRCGD AEMLLPAEYA QLAQINDTAV SIPLTTLSAL VDEQTRKTPD ATALADARHQ
LSYQEMREQV IALAHLLRER GVKPGDSVAV ALPRSVFLTL ALHGIVEAGA AWLPLDTGYP
DDRLRMMLED AQPKLLITTA EQLPRFNDIP GVESLCYNAL LPTSGAESLA LSLPHHTAYI
IFTSGSTGRP KGVMVGQTAI VNRLLWMQDH YPLTAEDVVA QKTPCSFDVS VWEFFWPFIA
GAKLVMAEPD AHRDPIAMQH FFAKYGVTTT HFVPSMLAAF VASLTPESAH ESCATLQRVF
CSGEALPTGL CREWEQLTGA PLHNLYGPTE AAVDVSWYPA CGKELADVTG NSVPIGYPVW
NTGLRILDAM MRPVPPGTAG DLYLTGIQLA QGYLGRPDLT ASRFIADPFM PGERMYRTGD
VARWLENGAV EYLGRSDDQL KIRGQRIELG EIDRVMQTLP DVEHAVAHAC VFNQAAATGG
DARQLVGYLV SQSGLPLDIP ALQERLRETL PPHMVPVVLL QLAELPLSAN GKLDRKALPM
PQLTQRTPGR APLPGTEKTV ADAFAGLLGC EVNDVEADFF ALGGHSLLAM KLAAQLSRAS
RRQVTPGQVM VASTVGQLSA LLDSADDEQS QRLGFETLLP LRESSGPTLF CFHPASGFAW
QFSVLARYLS PHWSITGIQS PRPDGPMQTA TNLDEVCERH LETLLAQQPH GPYYLLGYSL
GGTLAQGIAA RLRARGETVA FLGLLDTWPP ETQNWQEKEA NGLDPEVLAE IAREREAFLA
AQQGNASGEL FSTIEGNYAD AVRLLTTAHS VPFDGRATLF VAERTLPEGI SPERSWAPWM
AELDIYRQDC AHVDIISPAA FENIGPIIRA LLDQ
//
