ID   A8DRZ1_9BILA            Unreviewed;       183 AA.
AC   A8DRZ1;
DT   13-NOV-2007, integrated into UniProtKB/TrEMBL.
DT   13-NOV-2007, sequence version 1.
DT   27-MAR-2024, entry version 37.
DE   SubName: Full=Dyskerin {ECO:0000313|EMBL:ABM05797.1};
DE   Flags: Fragment;
GN   Name=DKC1 {ECO:0000313|EMBL:ABM05797.1};
OS   Saccoglossus bromophenolosus.
OC   Eukaryota; Metazoa; Hemichordata; Enteropneusta; Harrimaniidae;
OC   Saccoglossus.
OX   NCBI_TaxID=31193 {ECO:0000313|EMBL:ABM05797.1};
RN   [1] {ECO:0000313|EMBL:ABM05797.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=SJB173 {ECO:0000313|EMBL:ABM05797.1};
RX   PubMed=18692145; DOI=10.1016/j.ympev.2008.07.008;
RA   Bourlat S.J., Nielsen C., Economou A.D., Telford M.J.;
RT   "Testing the new animal phylogeny: a phylum level molecular analysis of the
RT   animal kingdom.";
RL   Mol. Phylogenet. Evol. 49:23-31(2008).
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DR   EMBL; DQ988739; ABM05797.1; -; mRNA.
DR   AlphaFoldDB; A8DRZ1; -.
DR   GO; GO:0009982; F:pseudouridine synthase activity; IEA:InterPro.
DR   GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR   GO; GO:0001522; P:pseudouridine synthesis; IEA:InterPro.
DR   GO; GO:0006396; P:RNA processing; IEA:InterPro.
DR   CDD; cd21148; PUA_Cbf5; 1.
DR   Gene3D; 3.30.2350.10; Pseudouridine synthase; 1.
DR   Gene3D; 2.30.130.10; PUA domain; 1.
DR   InterPro; IPR020103; PsdUridine_synth_cat_dom_sf.
DR   InterPro; IPR002478; PUA.
DR   InterPro; IPR015947; PUA-like_sf.
DR   InterPro; IPR036974; PUA_sf.
DR   InterPro; IPR004802; tRNA_PsdUridine_synth_B_fam.
DR   InterPro; IPR032819; TruB_C.
DR   NCBIfam; TIGR00425; CBF5; 1.
DR   PANTHER; PTHR23127; CENTROMERE/MICROTUBULE BINDING PROTEIN CBF5; 1.
DR   PANTHER; PTHR23127:SF0; H_ACA RIBONUCLEOPROTEIN COMPLEX SUBUNIT DKC1; 1.
DR   Pfam; PF01472; PUA; 1.
DR   Pfam; PF16198; TruB_C_2; 1.
DR   SUPFAM; SSF55120; Pseudouridine synthase; 1.
DR   SUPFAM; SSF88697; PUA domain-like; 1.
DR   PROSITE; PS50890; PUA; 1.
PE   2: Evidence at transcript level;
FT   DOMAIN          73..139
FT                   /note="tRNA pseudouridylate synthase B C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF16198"
FT   DOMAIN          143..182
FT                   /note="PUA"
FT                   /evidence="ECO:0000259|Pfam:PF01472"
FT   NON_TER         1
FT                   /evidence="ECO:0000313|EMBL:ABM05797.1"
FT   NON_TER         183
FT                   /evidence="ECO:0000313|EMBL:ABM05797.1"
SQ   SEQUENCE   183 AA;  20706 MW;  187B62688C1E171D CRC64;
     CVVRLHSAIE NEAKLARVIE TLTGAVFQRP PLISAVKRQL RVRTIYESKL LEYDEERHLG
     VVWISCEAGT YIRTLCVHMG LLLGVGGQMA ELRRVRSGIQ SESDNMVTMH DVMDARWQYD
     NNKDETYLRR VIKPLEALLV SHKRIVLKDS AVNAICYGAK IMLPGVLRFE DGIEVNSEVV
     VLS
//