ID A8DT04_HAPBU Unreviewed; 416 AA.
AC A8DT04;
DT 13-NOV-2007, integrated into UniProtKB/TrEMBL.
DT 13-NOV-2007, sequence version 1.
DT 24-JAN-2024, entry version 69.
DE SubName: Full=Evx-2 {ECO:0000313|EMBL:ABS70790.1};
GN Name=evx-2 {ECO:0000313|EMBL:ABS70790.1};
OS Haplochromis burtoni (Burton's mouthbrooder) (Chromis burtoni).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC Pseudocrenilabrinae; Haplochromini; Haplochromis.
OX NCBI_TaxID=8153 {ECO:0000313|EMBL:ABS70790.1};
RN [1] {ECO:0000313|EMBL:ABS70790.1}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=17845724; DOI=10.1186/1471-2164-8-317;
RA Hoegg S., Boore J.L., Kuehl J.V., Meyer A.;
RT "Comparative phylogenomic analyses of teleost fish Hox gene clusters:
RT lessons from the cichlid fish Astatotilapia burtoni.";
RL BMC Genomics 8:317-317(2007).
RN [2] {ECO:0000313|EMBL:ABS70790.1}
RP NUCLEOTIDE SEQUENCE.
RA Hoegg S., Boore J.L., Meyer A.;
RL Submitted (APR-2007) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC ECO:0000256|PROSITE-ProRule:PRU00108, ECO:0000256|RuleBase:RU000682}.
CC -!- SIMILARITY: Belongs to the even-skipped homeobox family.
CC {ECO:0000256|ARBA:ARBA00038449}.
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DR EMBL; EF594315; ABS70790.1; -; Genomic_DNA.
DR RefSeq; XP_005921533.1; XM_005921471.2.
DR AlphaFoldDB; A8DT04; -.
DR GeneID; 102312700; -.
DR CTD; 344191; -.
DR OrthoDB; 728401at2759; -.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; IEA:InterPro.
DR CDD; cd00086; homeodomain; 1.
DR Gene3D; 1.10.10.60; Homeodomain-like; 1.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR017970; Homeobox_CS.
DR InterPro; IPR001356; Homeobox_dom.
DR InterPro; IPR020479; Homeobox_metazoa.
DR PANTHER; PTHR46294:SF1; HOMEOBOX EVEN-SKIPPED HOMOLOG PROTEIN 2; 1.
DR PANTHER; PTHR46294; SEGMENTATION PROTEIN EVEN-SKIPPED; 1.
DR Pfam; PF00046; Homeodomain; 1.
DR PRINTS; PR00024; HOMEOBOX.
DR SMART; SM00389; HOX; 1.
DR SUPFAM; SSF46689; Homeodomain-like; 1.
DR PROSITE; PS00027; HOMEOBOX_1; 1.
DR PROSITE; PS50071; HOMEOBOX_2; 1.
PE 3: Inferred from homology;
KW Developmental protein {ECO:0000256|ARBA:ARBA00022473};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PROSITE-
KW ProRule:PRU00108};
KW Homeobox {ECO:0000256|ARBA:ARBA00023155, ECO:0000256|PROSITE-
KW ProRule:PRU00108};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|PROSITE-
KW ProRule:PRU00108}; Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 165..225
FT /note="Homeobox"
FT /evidence="ECO:0000259|PROSITE:PS50071"
FT DNA_BIND 167..226
FT /note="Homeobox"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00108"
FT REGION 75..164
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 76..111
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 129..164
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 416 AA; 44639 MW; E71B996ADFE72D20 CRC64;
MMERIRKEMI LMERGLHSPV AGKRLADTPG NSVLEALENS QHGGRLSPRI TSASLHGNLG
DIPTKSKFEI DSLFGTHHGS ENSSSAEISS SESRKKMSLY SEVSQESDIN SDVEVGCPAH
RSPSQHKENN KGFSDSSSGS SNTSSNSLQN MNGNSTVGSN NSNADQVRRY RTAFTREQIA
RLEKEFYREN YVSRPRRCEL AATLNLPETT IKVWFQNRRM KDKRQRLAMS WPHPADPSFY
TYMMTHAAAT GSLPYPFHSH MPLHYYPHVG VTAAAAAAAA TGAASSPFAT SIRPLDTFRA
LSHPYSRPEL LCSFRHPGLY QSPAGLNSSA AASAAAAAAA AAAAVSAPSA TGPCSCLSCH
SSQAASALGS RSASADFTCT ASGQRSESGF LPYSAAVLSK TSVPSPDQRE ETSLNR
//
