ID A8F9S3_BACP2 Unreviewed; 335 AA.
AC A8F9S3;
DT 13-NOV-2007, integrated into UniProtKB/TrEMBL.
DT 13-NOV-2007, sequence version 1.
DT 27-MAR-2024, entry version 87.
DE SubName: Full=Transcriptional regulator {ECO:0000313|EMBL:ABV60990.1};
GN OrderedLocusNames=BPUM_0292 {ECO:0000313|EMBL:ABV60990.1};
OS Bacillus pumilus (strain SAFR-032).
OC Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Bacillus.
OX NCBI_TaxID=315750 {ECO:0000313|EMBL:ABV60990.1, ECO:0000313|Proteomes:UP000001355};
RN [1] {ECO:0000313|EMBL:ABV60990.1, ECO:0000313|Proteomes:UP000001355}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SAFR-032 {ECO:0000313|EMBL:ABV60990.1,
RC ECO:0000313|Proteomes:UP000001355};
RX PubMed=17895969; DOI=10.1371/journal.pone.0000928;
RA Gioia J., Yerrapragada S., Qin X., Jiang H., Igboeli O.C., Muzny D.,
RA Dugan-Rocha S., Ding Y., Hawes A., Liu W., Perez L., Kovar C., Dinh H.,
RA Lee S., Nazareth L., Blyth P., Holder M., Buhay C., Tirumalai M.R., Liu Y.,
RA Dasgupta I., Bokhetache L., Fujita M., Karouia F., Eswara Moorthy P.,
RA Siefert J., Uzman A., Buzumbo P., Verma A., Zwiya H., McWilliams B.D.,
RA Olowu A., Clinkenbeard K.D., Newcombe D., Golebiewski L., Petrosino J.F.,
RA Nicholson W.L., Fox G.E., Venkateswaran K., Highlander S.K.,
RA Weinstock G.M.;
RT "Paradoxical DNA repair and peroxide resistance gene conservation in
RT Bacillus pumilus SAFR-032.";
RL PLoS ONE 2:E928-E928(2007).
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DR EMBL; CP000813; ABV60990.1; -; Genomic_DNA.
DR RefSeq; WP_012008860.1; NZ_VEIS01000004.1.
DR AlphaFoldDB; A8F9S3; -.
DR STRING; 315750.BPUM_0292; -.
DR KEGG; bpu:BPUM_0292; -.
DR eggNOG; COG1609; Bacteria.
DR HOGENOM; CLU_037628_6_0_9; -.
DR OrthoDB; 9788209at2; -.
DR Proteomes; UP000001355; Chromosome.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd01392; HTH_LacI; 1.
DR CDD; cd06267; PBP1_LacI_sugar_binding-like; 1.
DR Gene3D; 3.40.50.2300; -; 2.
DR Gene3D; 1.10.260.40; lambda repressor-like DNA-binding domains; 1.
DR InterPro; IPR000843; HTH_LacI.
DR InterPro; IPR046335; LacI/GalR-like_sensor.
DR InterPro; IPR010982; Lambda_DNA-bd_dom_sf.
DR InterPro; IPR028082; Peripla_BP_I.
DR PANTHER; PTHR30146:SF152; HTH-TYPE TRANSCRIPTIONAL REGULATOR EBGR-RELATED; 1.
DR PANTHER; PTHR30146; LACI-RELATED TRANSCRIPTIONAL REPRESSOR; 1.
DR Pfam; PF00356; LacI; 1.
DR Pfam; PF13377; Peripla_BP_3; 1.
DR SMART; SM00354; HTH_LACI; 1.
DR SUPFAM; SSF47413; lambda repressor-like DNA-binding domains; 1.
DR SUPFAM; SSF53822; Periplasmic binding protein-like I; 1.
DR PROSITE; PS00356; HTH_LACI_1; 1.
DR PROSITE; PS50932; HTH_LACI_2; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Repressor {ECO:0000256|ARBA:ARBA00022491};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 3..57
FT /note="HTH lacI-type"
FT /evidence="ECO:0000259|PROSITE:PS50932"
SQ SEQUENCE 335 AA; 36508 MW; 7EFC0850C0BCA17C CRC64;
MSVSIKDVAL KAGVSIASVS RVLSGKPGVG AQTAERIKQV IDELGYRPNL GARGLVKRKT
GNIAVVVPRG SYILNNPFFS TILDGIAKEL DETEFNMLMS FTSVQQQRLL ETQAVDGAIL
FSPRNEELSM DWLKSLAIPI IVVGSYLEDS PFPCVRPDDE EGVCQSVTAL FEKGHRTIGL
VNGPMSSMHS VRYYNGYERT LKHLGLTMNK ELVFELDEFD GGKVVEVVSQ FLQGNQHMTG
VVCSSDFLAM GVMKAADHAN VSIPHDLSVV GADDVPIASF LTPSLSSVHV DLVGMGRKAV
SLLTQVLDGD QLEEMEHIFP MYYIDRGTTG TPKKK
//
