ID A8FDX9_BACP2 Unreviewed; 226 AA.
AC A8FDX9;
DT 13-NOV-2007, integrated into UniProtKB/TrEMBL.
DT 13-NOV-2007, sequence version 1.
DT 27-MAR-2024, entry version 86.
DE SubName: Full=Crp/Fnr family transcriptional regulator {ECO:0000313|EMBL:ABV62446.1};
GN OrderedLocusNames=BPUM_1774 {ECO:0000313|EMBL:ABV62446.1};
OS Bacillus pumilus (strain SAFR-032).
OC Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Bacillus.
OX NCBI_TaxID=315750 {ECO:0000313|EMBL:ABV62446.1, ECO:0000313|Proteomes:UP000001355};
RN [1] {ECO:0000313|EMBL:ABV62446.1, ECO:0000313|Proteomes:UP000001355}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SAFR-032 {ECO:0000313|EMBL:ABV62446.1,
RC ECO:0000313|Proteomes:UP000001355};
RX PubMed=17895969; DOI=10.1371/journal.pone.0000928;
RA Gioia J., Yerrapragada S., Qin X., Jiang H., Igboeli O.C., Muzny D.,
RA Dugan-Rocha S., Ding Y., Hawes A., Liu W., Perez L., Kovar C., Dinh H.,
RA Lee S., Nazareth L., Blyth P., Holder M., Buhay C., Tirumalai M.R., Liu Y.,
RA Dasgupta I., Bokhetache L., Fujita M., Karouia F., Eswara Moorthy P.,
RA Siefert J., Uzman A., Buzumbo P., Verma A., Zwiya H., McWilliams B.D.,
RA Olowu A., Clinkenbeard K.D., Newcombe D., Golebiewski L., Petrosino J.F.,
RA Nicholson W.L., Fox G.E., Venkateswaran K., Highlander S.K.,
RA Weinstock G.M.;
RT "Paradoxical DNA repair and peroxide resistance gene conservation in
RT Bacillus pumilus SAFR-032.";
RL PLoS ONE 2:E928-E928(2007).
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DR EMBL; CP000813; ABV62446.1; -; Genomic_DNA.
DR RefSeq; WP_012010173.1; NZ_VEIS01000023.1.
DR AlphaFoldDB; A8FDX9; -.
DR STRING; 315750.BPUM_1774; -.
DR KEGG; bpu:BPUM_1774; -.
DR eggNOG; COG0664; Bacteria.
DR HOGENOM; CLU_075053_11_0_9; -.
DR OrthoDB; 581021at2; -.
DR Proteomes; UP000001355; Chromosome.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd00038; CAP_ED; 1.
DR Gene3D; 2.60.120.10; Jelly Rolls; 1.
DR InterPro; IPR000595; cNMP-bd_dom.
DR InterPro; IPR018490; cNMP-bd_dom_sf.
DR InterPro; IPR012318; HTH_CRP.
DR InterPro; IPR014710; RmlC-like_jellyroll.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR24567; CRP FAMILY TRANSCRIPTIONAL REGULATORY PROTEIN; 1.
DR PANTHER; PTHR24567:SF26; REGULATORY PROTEIN YEIL; 1.
DR Pfam; PF00027; cNMP_binding; 1.
DR Pfam; PF13545; HTH_Crp_2; 1.
DR SMART; SM00100; cNMP; 1.
DR SUPFAM; SSF51206; cAMP-binding domain-like; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS50042; CNMP_BINDING_3; 1.
DR PROSITE; PS51063; HTH_CRP_2; 1.
PE 4: Predicted;
KW Activator {ECO:0000256|ARBA:ARBA00023159}.
FT DOMAIN 15..116
FT /note="Cyclic nucleotide-binding"
FT /evidence="ECO:0000259|PROSITE:PS50042"
FT DOMAIN 149..214
FT /note="HTH crp-type"
FT /evidence="ECO:0000259|PROSITE:PS51063"
SQ SEQUENCE 226 AA; 26100 MW; BB4F5A130B168182 CRC64;
MEELHDESLF AYYMKAHQLE SVFHQKLMSH VSLCRYEQGE LVCSKGDKRE YLYLLVKGKL
KIFTTTKEGK TFILSFKHPL EAIGDIEYVQ QTDMVNTVEA VTEVHMLRVS HQALMRHAKD
DPRVLNFLLK GITNKFYTKS NDLSFHLLYP VEVRLASYLL SVVTSDESAS ALRLTDAASL
IGTSYRHINR VIQQFCEKGL IERRRGNITI SDRKGLLEIA EHNIYE
//
