ID A8FYL8_SHESH Unreviewed; 1020 AA.
AC A8FYL8;
DT 13-NOV-2007, integrated into UniProtKB/TrEMBL.
DT 13-NOV-2007, sequence version 1.
DT 27-MAR-2024, entry version 97.
DE SubName: Full=Diguanylate cyclase/phosphodiesterase with PAS/PAC and GAF sensor(S) {ECO:0000313|EMBL:ABV37941.1};
GN OrderedLocusNames=Ssed_3337 {ECO:0000313|EMBL:ABV37941.1};
OS Shewanella sediminis (strain HAW-EB3).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Alteromonadales;
OC Shewanellaceae; Shewanella.
OX NCBI_TaxID=425104 {ECO:0000313|EMBL:ABV37941.1, ECO:0000313|Proteomes:UP000002015};
RN [1] {ECO:0000313|EMBL:ABV37941.1, ECO:0000313|Proteomes:UP000002015}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=HAW-EB3 {ECO:0000313|EMBL:ABV37941.1,
RC ECO:0000313|Proteomes:UP000002015};
RG US DOE Joint Genome Institute;
RA Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E.,
RA Tice H., Pitluck S., Chertkov O., Brettin T., Bruce D., Detter J.C.,
RA Han C., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Kim E.,
RA Zhao J.-S., Richardson P.;
RT "Complete sequence of Shewanella sediminis HAW-EB3.";
RL Submitted (AUG-2007) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CP000821; ABV37941.1; -; Genomic_DNA.
DR RefSeq; WP_012143671.1; NC_009831.1.
DR AlphaFoldDB; A8FYL8; -.
DR STRING; 425104.Ssed_3337; -.
DR KEGG; sse:Ssed_3337; -.
DR eggNOG; COG2202; Bacteria.
DR eggNOG; COG5001; Bacteria.
DR HOGENOM; CLU_000445_70_20_6; -.
DR OrthoDB; 9176779at2; -.
DR Proteomes; UP000002015; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR GO; GO:0071555; P:cell wall organization; IEA:InterPro.
DR CDD; cd01948; EAL; 1.
DR CDD; cd01949; GGDEF; 1.
DR CDD; cd00130; PAS; 3.
DR Gene3D; 3.30.70.270; -; 1.
DR Gene3D; 3.20.20.450; EAL domain; 1.
DR Gene3D; 3.30.450.20; PAS domain; 3.
DR InterPro; IPR001633; EAL_dom.
DR InterPro; IPR035919; EAL_sf.
DR InterPro; IPR000160; GGDEF_dom.
DR InterPro; IPR029787; Nucleotide_cyclase.
DR InterPro; IPR001610; PAC.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR000700; PAS-assoc_C.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR013655; PAS_fold_3.
DR InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR InterPro; IPR011620; Sig_transdc_His_kinase_LytS_TM.
DR NCBIfam; TIGR00254; GGDEF; 1.
DR NCBIfam; TIGR00229; sensory_box; 3.
DR PANTHER; PTHR44757:SF2; BIOFILM ARCHITECTURE MAINTENANCE PROTEIN MBAA; 1.
DR PANTHER; PTHR44757; DIGUANYLATE CYCLASE DGCP; 1.
DR Pfam; PF07694; 5TM-5TMR_LYT; 1.
DR Pfam; PF00563; EAL; 1.
DR Pfam; PF00990; GGDEF; 1.
DR Pfam; PF08447; PAS_3; 2.
DR Pfam; PF13426; PAS_9; 1.
DR SMART; SM00052; EAL; 1.
DR SMART; SM00267; GGDEF; 1.
DR SMART; SM00086; PAC; 3.
DR SMART; SM00091; PAS; 3.
DR SUPFAM; SSF141868; EAL domain-like; 1.
DR SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 3.
DR PROSITE; PS50883; EAL; 1.
DR PROSITE; PS50887; GGDEF; 1.
DR PROSITE; PS50113; PAC; 3.
DR PROSITE; PS50112; PAS; 2.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000002015};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 6..24
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 36..58
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 70..92
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 104..124
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 136..155
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 167..186
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 276..327
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 328..400
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 404..457
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 454..505
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 527..579
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 611..744
FT /note="GGDEF"
FT /evidence="ECO:0000259|PROSITE:PS50887"
FT DOMAIN 753..1008
FT /note="EAL"
FT /evidence="ECO:0000259|PROSITE:PS50883"
SQ SEQUENCE 1020 AA; 116087 MW; E7B1C2D598D2A161 CRC64;
MDSDVIFSLV QNAALLLAMV FVYDAVPRKQ RHEYFFLWRI SVGTVIGGIT VTTMMTHWEY
QPGVFFDARS IILGISGLFF GGLPTFVAMV IASVYRFLEG GSGWWAGIGI IFSSGLLGSY
WRYYRKSFIA DLSFKELYAF GFILQVITLL WMFVLPFEMA ISILSRISFP ALIVYPIAFV
LLGLLLSRRL EIERDAKIQL QDDFIFRSQF NVGNIGIAIS SVDQHWIKVN PRMCQMLQYT
EEELLLKTWA EMTYFDDLQT DLNLFNRMLD GEFDEYEMDK RYVAKDGSIV YTHLTVACQR
VNNQVQLVIA GLLDITSQKQ AESAMSKSQE QLALVLDSSE LGLWDWDLKS DKVDRNDYCA
KLLGSGVEEL NDDGRLWINA IHPQDRLEVL HAMDKHLKGE NPQYTVEYRL NTFSGETRWI
LDRGKVASKD ANGAPLRVCG TNTDITDRKR GEESLQLAAS VYNNSSEAMS VQDSLGNIIT
INSAFTDITG YLEGEVLSKH IRILECDRTS KNQYEQMNMQ ITQTGRWQGE VWLKHKSGTE
FIVWLTINTI LDNKGEVYRR VALFSDITEK KQAEHIIWKQ ANYDPLTGLP NRRMLLEYLG
TELLKSDRNK KHFALMFLDL DYFKEVNDSL GHDIGDLLLV ETAKRLKGCI RESDVVARLG
GDEFTVVLSA IQDHKGVERV AENILSRLAE PFNLDNESAY ISASIGITLY PDDASSIDGL
LKHADQAMYA AKEQGRNRYH YFTPSMQEYA KYRMLLIRDL RKAIIRKEFE IYYQPIIELT
DSKVFKAEAL IRWHHPVRGV VSPGEFIPVA EETGLIIEIG NWVFEQAAKQ SAMWRERFGV
AIQISINKSP IQFRDEGESF VDWIEQLKKL NLESNGICVE ITEGLLLDAS MGVSEKLLAY
RDAGVQVSLD DFGTGYSSLA YLKKFDIDYL KIDQSFTRNL ETDSNDVTLC EAIIVMAHKL
GMKVIAEGVE TEYQKKILFE AGCDYGQGYL FSKPIPVADF EAKYLIGLTE LPNEKGSPSQ
//
