ID A8G8B1_SERP5 Unreviewed; 316 AA.
AC A8G8B1;
DT 13-NOV-2007, integrated into UniProtKB/TrEMBL.
DT 13-NOV-2007, sequence version 1.
DT 27-MAR-2024, entry version 94.
DE RecName: Full=HTH-type transcriptional regulator MetR {ECO:0000256|ARBA:ARBA00019365};
GN OrderedLocusNames=Spro_0241 {ECO:0000313|EMBL:ABV39351.1};
OS Serratia proteamaculans (strain 568).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC Yersiniaceae; Serratia.
OX NCBI_TaxID=399741 {ECO:0000313|EMBL:ABV39351.1};
RN [1] {ECO:0000313|EMBL:ABV39351.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=568 {ECO:0000313|EMBL:ABV39351.1};
RG US DOE Joint Genome Institute;
RA Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E.,
RA Tice H., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J.,
RA Larimer F., Land M., Hauser L., Kyrpides N., Kim E., Taghavi S., Newman L.,
RA Vangronsveld J., van der Lelie D., Richardson P.;
RT "Complete sequence of chromosome of Serratia proteamaculans 568.";
RL Submitted (SEP-2007) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC -!- SIMILARITY: Belongs to the LysR transcriptional regulatory family.
CC {ECO:0000256|ARBA:ARBA00009437}.
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DR EMBL; CP000826; ABV39351.1; -; Genomic_DNA.
DR AlphaFoldDB; A8G8B1; -.
DR STRING; 399741.Spro_0241; -.
DR KEGG; spe:Spro_0241; -.
DR eggNOG; COG0583; Bacteria.
DR HOGENOM; CLU_039613_6_0_6; -.
DR OrthoDB; 155872at2; -.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0009086; P:methionine biosynthetic process; IEA:UniProtKB-KW.
DR CDD; cd08441; PBP2_MetR; 1.
DR Gene3D; 3.40.190.10; Periplasmic binding protein-like II; 2.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR005119; LysR_subst-bd.
DR InterPro; IPR037406; MetR_PBP2.
DR InterPro; IPR000847; Tscrpt_reg_HTH_LysR.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR30126; HTH-TYPE TRANSCRIPTIONAL REGULATOR; 1.
DR PANTHER; PTHR30126:SF25; HTH-TYPE TRANSCRIPTIONAL REGULATOR METR; 1.
DR Pfam; PF00126; HTH_1; 1.
DR Pfam; PF03466; LysR_substrate; 1.
DR PRINTS; PR00039; HTHLYSR.
DR SUPFAM; SSF53850; Periplasmic binding protein-like II; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS50931; HTH_LYSR; 1.
PE 3: Inferred from homology;
KW Amino-acid biosynthesis {ECO:0000256|ARBA:ARBA00022605};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Methionine biosynthesis {ECO:0000256|ARBA:ARBA00023167};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 2..59
FT /note="HTH lysR-type"
FT /evidence="ECO:0000259|PROSITE:PS50931"
SQ SEQUENCE 316 AA; 35492 MW; 89A779EBDF171318 CRC64;
MIELKHLRTL QALRNTGSLA AAAAQLHQTQ SALSHQFSDL EQRLGFKLFV RKSQPLRFTA
QGEILLQLAE QVLPQIQQAL QTCHEPHQAT LRIAIECHSC IQWLTPALDN FRQSWPQVVM
DFKSGVTFDP QPALQQGELD LVLTSDILPR SGLHYSPMFD FEVRLVLAPD HPLASKLHIE
PEDLIDETLM IYPVQRQRLD IWRHFLQPAG ISPALKNVDN TLLLIQMVSA RMGIAALPHW
VVESFERQGL VVTKTLGDGL WSRLYAAVRD GEQRQAVTEA FIRSARQHAC NHLPFVRDAA
RPSAGVASVK PLASQP
//
