ID A8H343_SHEPA Unreviewed; 322 AA.
AC A8H343;
DT 13-NOV-2007, integrated into UniProtKB/TrEMBL.
DT 13-NOV-2007, sequence version 1.
DT 27-MAR-2024, entry version 70.
DE SubName: Full=Dihydrodipicolinate synthetase {ECO:0000313|EMBL:ABV86980.1};
GN OrderedLocusNames=Spea_1655 {ECO:0000313|EMBL:ABV86980.1};
OS Shewanella pealeana (strain ATCC 700345 / ANG-SQ1).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Alteromonadales;
OC Shewanellaceae; Shewanella.
OX NCBI_TaxID=398579 {ECO:0000313|EMBL:ABV86980.1, ECO:0000313|Proteomes:UP000002608};
RN [1] {ECO:0000313|EMBL:ABV86980.1, ECO:0000313|Proteomes:UP000002608}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 700345 / ANG-SQ1 {ECO:0000313|Proteomes:UP000002608};
RG US DOE Joint Genome Institute;
RA Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E.,
RA Tice H., Pitluck S., Chertkov O., Brettin T., Bruce D., Detter J.C.,
RA Han C., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Kim E.,
RA Zhao J.-S.Z., Manno D., Hawari J., Richardson P.;
RT "Complete sequence of Shewanella pealeana ATCC 700345.";
RL Submitted (OCT-2007) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the DapA family.
CC {ECO:0000256|PIRNR:PIRNR001365}.
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DR EMBL; CP000851; ABV86980.1; -; Genomic_DNA.
DR AlphaFoldDB; A8H343; -.
DR STRING; 398579.Spea_1655; -.
DR KEGG; spl:Spea_1655; -.
DR eggNOG; COG0329; Bacteria.
DR HOGENOM; CLU_873444_0_0_6; -.
DR OrthoDB; 7157803at2; -.
DR Proteomes; UP000002608; Chromosome.
DR GO; GO:0016829; F:lyase activity; IEA:UniProtKB-KW.
DR CDD; cd00408; DHDPS-like; 1.
DR Gene3D; 3.20.20.70; Aldolase class I; 1.
DR InterPro; IPR013785; Aldolase_TIM.
DR InterPro; IPR002220; DapA-like.
DR PANTHER; PTHR12128:SF72; 4-HYDROXY-2-OXOGLUTARATE ALDOLASE, MITOCHONDRIAL; 1.
DR PANTHER; PTHR12128; DIHYDRODIPICOLINATE SYNTHASE; 1.
DR Pfam; PF00701; DHDPS; 1.
DR PIRSF; PIRSF001365; DHDPS; 1.
DR SMART; SM01130; DHDPS; 1.
DR SUPFAM; SSF51569; Aldolase; 1.
PE 3: Inferred from homology;
KW Lyase {ECO:0000256|ARBA:ARBA00023239, ECO:0000256|PIRNR:PIRNR001365};
KW Reference proteome {ECO:0000313|Proteomes:UP000002608}.
FT ACT_SITE 155
FT /note="Proton donor/acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR001365-1"
FT ACT_SITE 184
FT /note="Schiff-base intermediate with substrate"
FT /evidence="ECO:0000256|PIRSR:PIRSR001365-1"
FT BINDING 225
FT /ligand="pyruvate"
FT /ligand_id="ChEBI:CHEBI:15361"
FT /evidence="ECO:0000256|PIRSR:PIRSR001365-2"
SQ SEQUENCE 322 AA; 34592 MW; 4ED78467006239AE CRC64;
METNNTDWRY TVMPAVFTWL KESESGAVEI DLEATQKYAA DILNVQGKGG SRMGGLVGSG
TLGENSYLSS DQRLSLLKAL SDVAKQYNVP LISGAAAETK EDLAKIVTEL ATVGVDTVMV
MPPKTKEAPS DEDMYAYYEL SAIAAKEAGI TIMPYNNPDA AGYHALSTDI LRKLAALPEV
TALKISTTDV STIETLMLEN KDLKILAGVD TVTVHAGLAG ACGGITGVGC VFPKASVSMQ
EYVNNGEWAE ANKISQAMNS ISYLDAQPLL MEYLKFAFGI HHNDADGGLR TLGKKLTQEQ
IDDVRARYLL AKERLEVLGL AD
//
