ID A8IC78_AZOC5 Unreviewed; 452 AA.
AC A8IC78;
DT 04-DEC-2007, integrated into UniProtKB/TrEMBL.
DT 04-DEC-2007, sequence version 1.
DT 27-MAR-2024, entry version 83.
DE SubName: Full=Xenobiotic compound monooxygenase A subunit {ECO:0000313|EMBL:BAF89170.1};
GN Name=dszA {ECO:0000313|EMBL:BAF89170.1};
GN OrderedLocusNames=AZC_3172 {ECO:0000313|EMBL:BAF89170.1};
OS Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG
OS 6465 / NBRC 14845 / NCIMB 13405 / ORS 571).
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Hyphomicrobiales;
OC Xanthobacteraceae; Azorhizobium.
OX NCBI_TaxID=438753 {ECO:0000313|EMBL:BAF89170.1, ECO:0000313|Proteomes:UP000000270};
RN [1] {ECO:0000313|EMBL:BAF89170.1, ECO:0000313|Proteomes:UP000000270}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 /
RC NCIMB 13405 / ORS 571 {ECO:0000313|Proteomes:UP000000270};
RX PubMed=17720818; DOI=10.1128/AEM.01514-07;
RA Suzuki S., Aono T., Lee KB., Suzuki T., Liu CT., Miwa H., Wakao S., Iki T.,
RA Oyaizu H.;
RT "Rhizobial factors required for stem nodule maturation and maintenance in
RT Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.";
RL Appl. Environ. Microbiol. 73:6650-6659(2007).
RN [2] {ECO:0000313|Proteomes:UP000000270}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 /
RC NCIMB 13405 / ORS 571 {ECO:0000313|Proteomes:UP000000270};
RA Lee K.B., Backer P.D., Aono T., Liu C.T., Suzuki S., Suzuki T., Kaneko T.,
RA Yamada M., Tabata S., Kupfer D.M., Najar F.Z., Wiley G.B., Roe B.,
RA Binnewies T., Ussery D., Vereecke D., Gevers D., Holsters M., Oyaizu H.;
RT "Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium
RT caulinodans ORS571.";
RL Submitted (APR-2007) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EMBL:BAF89170.1, ECO:0000313|Proteomes:UP000000270}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 /
RC NCIMB 13405 / ORS 571 {ECO:0000313|Proteomes:UP000000270};
RX PubMed=18522759; DOI=10.1186/1471-2164-9-271;
RA Lee KB., Backer P.D., Aono T., Liu CT., Suzuki S., Suzuki T., Kaneko T.,
RA Yamada M., Tabata S., Kupfer D.M., Najar F.Z., Wiley G.B., Roe B.,
RA Binnewies T.T., Ussery D.W., D'Haeze W., Herder J.D., Gevers D.,
RA Vereecke D., Holsters M., Oyaizu H.;
RT "The genome of the versatile nitrogen fixer Azorhizobium caulinodans
RT ORS571.";
RL BMC Genomics 9:271-271(2008).
RN [4] {ECO:0000313|EMBL:BAF89170.1, ECO:0000313|Proteomes:UP000000270}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 /
RC NCIMB 13405 / ORS 571 {ECO:0000313|Proteomes:UP000000270};
RX PubMed=19542345; DOI=10.1128/AEM.00398-09;
RA Tsukada S., Aono T., Akiba N., Lee KB., Liu CT., Toyazaki H., Oyaizu H.;
RT "Comparative genome-wide transcriptional profiling of Azorhizobium
RT caulinodans ORS571 grown under free-living and symbiotic conditions.";
RL Appl. Environ. Microbiol. 75:5037-5046(2009).
RN [5] {ECO:0000313|EMBL:BAF89170.1, ECO:0000313|Proteomes:UP000000270}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 /
RC NCIMB 13405 / ORS 571 {ECO:0000313|Proteomes:UP000000270};
RX PubMed=20382809; DOI=10.1128/AEM.00238-10;
RA Akiba N., Aono T., Toyazaki H., Sato S., Oyaizu H.;
RT "phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for
RT symbiosis with Sesbania rostrata and is involved in expression of reb
RT genes.";
RL Appl. Environ. Microbiol. 76:3475-3485(2010).
RN [6] {ECO:0000313|EMBL:BAF89170.1, ECO:0000313|Proteomes:UP000000270}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 /
RC NCIMB 13405 / ORS 571 {ECO:0000313|Proteomes:UP000000270};
RX PubMed=21571889; DOI=10.1128/AEM.02327-10;
RA Liu CT., Lee KB., Wang YS., Peng MH., Lee KT., Suzuki S., Suzuki T.,
RA Oyaizu H.;
RT "Involvement of the azorhizobial chromosome partition gene (parA) in the
RT onset of bacteroid differentiation during Sesbania rostrata stem nodule
RT development.";
RL Appl. Environ. Microbiol. 77:4371-4382(2011).
CC -!- SIMILARITY: Belongs to the NtaA/SnaA/DszA monooxygenase family.
CC {ECO:0000256|ARBA:ARBA00033748}.
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DR EMBL; AP009384; BAF89170.1; -; Genomic_DNA.
DR RefSeq; WP_012171696.1; NC_009937.1.
DR AlphaFoldDB; A8IC78; -.
DR STRING; 438753.AZC_3172; -.
DR KEGG; azc:AZC_3172; -.
DR eggNOG; COG2141; Bacteria.
DR HOGENOM; CLU_022256_1_2_5; -.
DR Proteomes; UP000000270; Chromosome.
DR GO; GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.
DR GO; GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro.
DR CDD; cd01095; Nitrilotriacetate_monoxgenase; 1.
DR Gene3D; 3.20.20.30; Luciferase-like domain; 1.
DR InterPro; IPR011251; Luciferase-like_dom.
DR InterPro; IPR036661; Luciferase-like_sf.
DR InterPro; IPR016215; NTA_MOA.
DR NCBIfam; TIGR03860; FMN_nitrolo; 1.
DR PANTHER; PTHR30011; ALKANESULFONATE MONOOXYGENASE-RELATED; 1.
DR PANTHER; PTHR30011:SF16; C2H2 FINGER DOMAIN TRANSCRIPTION FACTOR (EUROFUNG)-RELATED; 1.
DR Pfam; PF00296; Bac_luciferase; 1.
DR PIRSF; PIRSF000337; NTA_MOA; 1.
DR SUPFAM; SSF51679; Bacterial luciferase-like; 1.
PE 3: Inferred from homology;
KW Flavoprotein {ECO:0000256|PIRSR:PIRSR000337-1};
KW FMN {ECO:0000256|PIRSR:PIRSR000337-1};
KW Monooxygenase {ECO:0000313|EMBL:BAF89170.1};
KW Oxidoreductase {ECO:0000313|EMBL:BAF89170.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000000270}.
FT DOMAIN 20..384
FT /note="Luciferase-like"
FT /evidence="ECO:0000259|Pfam:PF00296"
FT REGION 433..452
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT BINDING 58
FT /ligand="FMN"
FT /ligand_id="ChEBI:CHEBI:58210"
FT /evidence="ECO:0000256|PIRSR:PIRSR000337-1"
FT BINDING 100
FT /ligand="FMN"
FT /ligand_id="ChEBI:CHEBI:58210"
FT /evidence="ECO:0000256|PIRSR:PIRSR000337-1"
FT BINDING 150
FT /ligand="FMN"
FT /ligand_id="ChEBI:CHEBI:58210"
FT /evidence="ECO:0000256|PIRSR:PIRSR000337-1"
FT BINDING 154
FT /ligand="FMN"
FT /ligand_id="ChEBI:CHEBI:58210"
FT /evidence="ECO:0000256|PIRSR:PIRSR000337-1"
FT BINDING 225
FT /ligand="FMN"
FT /ligand_id="ChEBI:CHEBI:58210"
FT /evidence="ECO:0000256|PIRSR:PIRSR000337-1"
SQ SEQUENCE 452 AA; 49716 MW; EC28B24183B9205C CRC64;
MTAKRQIKLG AFLMTDGHHI AAWRHPRAPA NANVRIDHYL RLARIAEAAK FDALFLADSV
GVRNEDLASL SHTSRAVAFE PLTLLSALSV VTQNIGLIGT ASTTFNEPYH IARKFASLDL
LSGGRAGWNV VTSSSEAEAY NFNLDKHVAH ADRYDRAREF VSVVKGLWNT WEDDAFLRDK
LGGTYFDAEK FHLLDHRGKH FRVKGPLNVA RSPQGHPVVV QAGASEDGRD LAGATAEAIF
AAQRTLAEAQ AFYADIKGRA ENYGRNPDHV KIMPGVFPVV GASEAEAREK FEELQSGIEP
VVGLQLLSQV LGGFDLSGYP VDGPLPELPE TNGPKSRQKL LIDAARRDNL TIRQLYLEIA
GARGHWQVVG TPKQIADQLE ERFTKGAADG FNVMAPHLPG GLEDFIEFVV PELRRRGLFR
TEYEGTTLRE NLGLPFPQHQ APRARPQVVA AE
//
