ID A8JI07_CHLRE Unreviewed; 954 AA.
AC A8JI07;
DT 04-DEC-2007, integrated into UniProtKB/TrEMBL.
DT 04-DEC-2007, sequence version 1.
DT 24-JAN-2024, entry version 84.
DE SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:PNW71110.1};
GN ORFNames=CHLRE_17g746997v5 {ECO:0000313|EMBL:PNW71110.1};
OS Chlamydomonas reinhardtii (Chlamydomonas smithii).
OC Eukaryota; Viridiplantae; Chlorophyta; core chlorophytes; Chlorophyceae;
OC CS clade; Chlamydomonadales; Chlamydomonadaceae; Chlamydomonas.
OX NCBI_TaxID=3055 {ECO:0000313|EMBL:PNW71110.1, ECO:0000313|Proteomes:UP000006906};
RN [1] {ECO:0000313|EMBL:PNW71110.1, ECO:0000313|Proteomes:UP000006906}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CC-503 {ECO:0000313|Proteomes:UP000006906};
RX PubMed=17932292; DOI=10.1126/science.1143609;
RA Merchant S.S., Prochnik S.E., Vallon O., Harris E.H., Karpowicz S.J.,
RA Witman G.B., Terry A., Salamov A., Fritz-Laylin L.K., Marechal-Drouard L.,
RA Marshall W.F., Qu L.H., Nelson D.R., Sanderfoot A.A., Spalding M.H.,
RA Kapitonov V.V., Ren Q., Ferris P., Lindquist E., Shapiro H., Lucas S.M.,
RA Grimwood J., Schmutz J., Cardol P., Cerutti H., Chanfreau G., Chen C.L.,
RA Cognat V., Croft M.T., Dent R., Dutcher S., Fernandez E., Fukuzawa H.,
RA Gonzalez-Ballester D., Gonzalez-Halphen D., Hallmann A., Hanikenne M.,
RA Hippler M., Inwood W., Jabbari K., Kalanon M., Kuras R., Lefebvre P.A.,
RA Lemaire S.D., Lobanov A.V., Lohr M., Manuell A., Meier I., Mets L.,
RA Mittag M., Mittelmeier T., Moroney J.V., Moseley J., Napoli C.,
RA Nedelcu A.M., Niyogi K., Novoselov S.V., Paulsen I.T., Pazour G.,
RA Purton S., Ral J.P., Riano-Pachon D.M., Riekhof W., Rymarquis L.,
RA Schroda M., Stern D., Umen J., Willows R., Wilson N., Zimmer S.L.,
RA Allmer J., Balk J., Bisova K., Chen C.J., Elias M., Gendler K., Hauser C.,
RA Lamb M.R., Ledford H., Long J.C., Minagawa J., Page M.D., Pan J.,
RA Pootakham W., Roje S., Rose A., Stahlberg E., Terauchi A.M., Yang P.,
RA Ball S., Bowler C., Dieckmann C.L., Gladyshev V.N., Green P., Jorgensen R.,
RA Mayfield S., Mueller-Roeber B., Rajamani S., Sayre R.T., Brokstein P.,
RA Dubchak I., Goodstein D., Hornick L., Huang Y.W., Jhaveri J., Luo Y.,
RA Martinez D., Ngau W.C., Otillar B., Poliakov A., Porter A., Szajkowski L.,
RA Werner G., Zhou K., Grigoriev I.V., Rokhsar D.S., Grossman A.R.;
RT "The Chlamydomonas genome reveals the evolution of key animal and plant
RT functions.";
RL Science 318:245-250(2007).
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DR EMBL; CM008978; PNW71110.1; -; Genomic_DNA.
DR RefSeq; XP_001703585.1; XM_001703533.1.
DR AlphaFoldDB; A8JI07; -.
DR STRING; 3055.A8JI07; -.
DR PaxDb; 3055-EDO96497; -.
DR ProMEX; A8JI07; -.
DR EnsemblPlants; PNW71110; PNW71110; CHLRE_17g746997v5.
DR Gramene; PNW71110; PNW71110; CHLRE_17g746997v5.
DR eggNOG; KOG3857; Eukaryota.
DR HOGENOM; CLU_007207_1_0_1; -.
DR InParanoid; A8JI07; -.
DR OrthoDB; 5473018at2759; -.
DR BioCyc; CHLAMY:GIO2-535-MONOMER; -.
DR BioCyc; MetaCyc:GIO2-535-MONOMER; -.
DR Proteomes; UP000006906; Chromosome 17.
DR ExpressionAtlas; A8JI07; baseline.
DR GO; GO:0005739; C:mitochondrion; IBA:GO_Central.
DR GO; GO:0004022; F:alcohol dehydrogenase (NAD+) activity; IBA:GO_Central.
DR GO; GO:0046872; F:metal ion binding; IEA:InterPro.
DR GO; GO:0016620; F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor; IEA:InterPro.
DR CDD; cd08178; AAD_C; 1.
DR CDD; cd07122; ALDH_F20_ACDH; 1.
DR Gene3D; 3.40.50.1970; -; 1.
DR Gene3D; 1.20.1090.10; Dehydroquinate synthase-like - alpha domain; 1.
DR InterPro; IPR034789; AAD_C.
DR InterPro; IPR001670; ADH_Fe/GldA.
DR InterPro; IPR018211; ADH_Fe_CS.
DR InterPro; IPR039697; Alcohol_dehydrogenase_Fe.
DR InterPro; IPR016161; Ald_DH/histidinol_DH.
DR InterPro; IPR016163; Ald_DH_C.
DR InterPro; IPR016162; Ald_DH_N.
DR InterPro; IPR015590; Aldehyde_DH_dom.
DR PANTHER; PTHR11496; ALCOHOL DEHYDROGENASE; 1.
DR PANTHER; PTHR11496:SF83; HYDROXYACID-OXOACID TRANSHYDROGENASE, MITOCHONDRIAL; 1.
DR Pfam; PF00171; Aldedh; 1.
DR Pfam; PF00465; Fe-ADH; 1.
DR SUPFAM; SSF53720; ALDH-like; 1.
DR SUPFAM; SSF56796; Dehydroquinate synthase-like; 1.
DR PROSITE; PS00913; ADH_IRON_1; 1.
DR PROSITE; PS00060; ADH_IRON_2; 1.
PE 4: Predicted;
KW Iron {ECO:0000256|ARBA:ARBA00023004};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000006906}.
FT DOMAIN 84..353
FT /note="Aldehyde dehydrogenase"
FT /evidence="ECO:0000259|Pfam:PF00171"
FT DOMAIN 533..927
FT /note="Alcohol dehydrogenase iron-type/glycerol
FT dehydrogenase GldA"
FT /evidence="ECO:0000259|Pfam:PF00465"
SQ SEQUENCE 954 AA; 102233 MW; 5AACA154ECB172CD CRC64;
MMSSSLVSGK RVAVPSAAKP CAAVPLPRVA GRRTAARVVC EAAPSGAAPA SPKAEAAAPV
AAAPATPHAE VKKERAPATD EALTELKALL KRAQTAQAQY STYTQEQVDE IFRAAAEAAN
AARIPLAKMA VEETRMGVAE DKVVKNHFAS EFIYNKYKHT KTCGVIEHDP AGGIQKVAEP
VGVIAGIVPT TNPTSTAIFK SLLSLKTRNA LVLCPHPRAA KSTIAAARIV RDAAVAAGAP
PNIISWVETP SLPVSQALMQ ATEINLILAT GGPAMVRAAY SSGNPSLGVG AGNTPALIDE
TADVAMAVSS ILLSKTFDNG VICASEQSVV VVAKAYDAVR TEFVRRGAYF LTEDDKVKVR
AGVVVDGKLN PNIVGQSIPK LAALFGIKVP QGTKVLIGEV EKIGPEEALS QEKLCPILAM
YRAPDYDHGV KMACELIMYG GAGHTSVLYT NPLNNAHIQQ YQSAVKTVRI LINTPASQGA
IGDLYNFHLD PSLTLGCGTW GSTSVSTNVG PQHLLNIKTV TARRENMLWF RVPPKIYFKG
GCLEVALTDL RGKSRAFIVT DKPLFDMGYA DKVTHILDSI NVHHQVFYHV TPDPTLACIE
AGLKEILEFK PDVIIALGGG SPMDAAKIMW LMYECPDTRF DGLAMRFMDI RKRVYEVPEL
GKKATMVCIP TTSGTGSEVT PFSVVTDERL GAKYPLADYA LTPSMAIVDP QLVLNMPKKL
TAWGGIDALT HALESYVSIC ATDYTKGLSR EAISLLFKYL PRAYANGSND YLAREKVHYA
ATIAGMAFAN AFLGICHSMA HKLGAAYHVP HGLANAALIS HVIRYNATDM PAKQAAFPQY
EYPTAKQDYA DLANMLGLGG NTVDEKVIKL IEAVEELKAK VDIPPTIKEI FNDPKVDADF
LANVDALAED AFDDQCTGAN PRYPLMADLK QLYLDAHAAP ILPVKTLEFF SKIN
//
