ID   A8K899_HUMAN            Unreviewed;       432 AA.
AC   A8K899;
DT   04-DEC-2007, integrated into UniProtKB/TrEMBL.
DT   04-DEC-2007, sequence version 1.
DT   22-FEB-2023, entry version 55.
DE   RecName: Full=Transcriptional adapter 3 {ECO:0000256|ARBA:ARBA00018537};
DE   AltName: Full=ADA3 homolog {ECO:0000256|ARBA:ARBA00033410};
DE   AltName: Full=Transcriptional adapter 3-like {ECO:0000256|ARBA:ARBA00031544};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|EMBL:BAF84953.1};
RN   [1] {ECO:0000313|EMBL:BAF84953.1}
RP   NUCLEOTIDE SEQUENCE.
RC   TISSUE=Testis {ECO:0000313|EMBL:BAF84953.1};
RA   Wakamatsu A., Yamamoto J., Kimura K., Ishii S., Watanabe K., Sugiyama A.,
RA   Murakawa K., Kaida T., Tsuchiya K., Fukuzumi Y., Kumagai A., Oishi Y.,
RA   Yamamoto S., Ono Y., Komori Y., Yamazaki M., Kisu Y., Nishikawa T.,
RA   Sugano S., Nomura N., Isogai T.;
RT   "NEDO human cDNA sequencing project.";
RL   Submitted (OCT-2007) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC   -!- SIMILARITY: Belongs to the NGG1 family.
CC       {ECO:0000256|ARBA:ARBA00005330}.
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DR   EMBL; AK292264; BAF84953.1; -; mRNA.
DR   RefSeq; NP_001265199.1; NM_001278270.1.
DR   RefSeq; NP_006345.1; NM_006354.3.
DR   RefSeq; NP_597814.1; NM_133480.2.
DR   AlphaFoldDB; A8K899; -.
DR   PeptideAtlas; A8K899; -.
DR   DNASU; 10474; -.
DR   GeneID; 10474; -.
DR   KEGG; hsa:10474; -.
DR   CTD; 10474; -.
DR   OrthoDB; 12488at2759; -.
DR   BioGRID-ORCS; 10474; 351 hits in 1183 CRISPR screens.
DR   GenomeRNAi; 10474; -.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   InterPro; IPR019340; Histone_AcTrfase_su3.
DR   PANTHER; PTHR13556:SF2; TRANSCRIPTIONAL ADAPTER 3; 1.
DR   PANTHER; PTHR13556; TRANSCRIPTIONAL ADAPTER 3-RELATED; 1.
DR   Pfam; PF10198; Ada3; 1.
PE   2: Evidence at transcript level;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW   Transcription {ECO:0000256|ARBA:ARBA00023163};
KW   Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT   REGION          87..126
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          272..319
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          370..397
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COMPBIAS        87..109
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        291..310
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   432 AA;  48883 MW;  FEBD1FAB6E7F102E CRC64;
     MSELKDCPLQ FHDFKSVDHL KVCPRYTAVL ARSEDDGIGI EELDTLQLEL ETLLSSASRR
     LRVLEAETQI LTDWQDKKGD RRFLKLGRDH ELGAPPKHGK PKKQKLEGKA GHGPGPGPGR
     PKSKNLQPKI QEYEFTDDPI DVPRIPKNDA PNRFWASVEP YCADITSEEV RTLEELLKPP
     EDEAEHYKIP PLGKHYSQHW AQEDLLEEQK DGARAAAVAD KKKGLMGPLT ELDTKDVDAL
     LKKSEAQHEQ PEDGCPFGAL TQRLLQALVE ENIISPMEDS PIPDMSGKES GADGASTSPR
     NQNKPFSVPH TKSLESRIKE ELIAQGLLES EDRPAEDSED EVLAELRKRQ AELKALSAHN
     RTKKHDLLRL AKEEVSRQEL RQRVRMADNE VMDAFRKIMA ARQKKRTPTK KEKDQAWKTL
     KERESILKLL DG
//