ID A8L0I4_FRASN Unreviewed; 540 AA.
AC A8L0I4;
DT 04-DEC-2007, integrated into UniProtKB/TrEMBL.
DT 04-DEC-2007, sequence version 1.
DT 27-MAR-2024, entry version 95.
DE SubName: Full=Transcriptional regulator, TetR family {ECO:0000313|EMBL:ABW13079.1};
GN ORFNames=Franean1_3682 {ECO:0000313|EMBL:ABW13079.1};
OS Frankia sp. (strain EAN1pec).
OC Bacteria; Actinomycetota; Actinomycetes; Frankiales; Frankiaceae; Frankia.
OX NCBI_TaxID=298653 {ECO:0000313|EMBL:ABW13079.1};
RN [1] {ECO:0000313|EMBL:ABW13079.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=EAN1.pec {ECO:0000313|EMBL:ABW13079.1};
RG US DOE Joint Genome Institute;
RA Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Hammon N.,
RA Israni S., Dalin E., Tice H., Pitluck S., Saunders E., Brettin T.,
RA Bruce D., Detter J.C., Han C., Schmutz J., Larimer F., Land M., Hauser L.,
RA Kyrpides N., Kim E., Rawnsley T., Niemann J., Benson D.R., Huang Y.,
RA Mastronunzio J., Bassi C.A., Tisa L.S., Richardson P.;
RT "Complete sequence of Frankia sp. EAN1pec.";
RL Submitted (AUG-2007) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; CP000820; ABW13079.1; -; Genomic_DNA.
DR AlphaFoldDB; A8L0I4; -.
DR STRING; 298653.Franean1_3682; -.
DR KEGG; fre:Franean1_3682; -.
DR eggNOG; COG0667; Bacteria.
DR eggNOG; COG1309; Bacteria.
DR HOGENOM; CLU_504094_0_0_11; -.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR Gene3D; 1.10.10.60; Homeodomain-like; 1.
DR Gene3D; 3.20.20.100; NADP-dependent oxidoreductase domain; 1.
DR Gene3D; 1.10.357.10; Tetracycline Repressor, domain 2; 1.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR001647; HTH_TetR.
DR InterPro; IPR023210; NADP_OxRdtase_dom.
DR InterPro; IPR036812; NADP_OxRdtase_dom_sf.
DR InterPro; IPR036271; Tet_transcr_reg_TetR-rel_C_sf.
DR InterPro; IPR039536; TetR_C_Proteobacteria.
DR PANTHER; PTHR43364:SF4; NAD(P)-LINKED OXIDOREDUCTASE SUPERFAMILY PROTEIN; 1.
DR PANTHER; PTHR43364; NADH-SPECIFIC METHYLGLYOXAL REDUCTASE-RELATED; 1.
DR Pfam; PF00248; Aldo_ket_red; 1.
DR Pfam; PF14246; TetR_C_7; 1.
DR Pfam; PF00440; TetR_N; 1.
DR PRINTS; PR00455; HTHTETR.
DR SUPFAM; SSF46689; Homeodomain-like; 1.
DR SUPFAM; SSF51430; NAD(P)-linked oxidoreductase; 1.
DR SUPFAM; SSF48498; Tetracyclin repressor-like, C-terminal domain; 1.
DR PROSITE; PS50977; HTH_TETR_2; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|PROSITE-ProRule:PRU00335};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 21..81
FT /note="HTH tetR-type"
FT /evidence="ECO:0000259|PROSITE:PS50977"
FT DNA_BIND 44..63
FT /note="H-T-H motif"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00335"
FT REGION 217..238
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 540 AA; 57694 MW; 52DE4B98ECA86842 CRC64;
MESRAGGERS RAGRPTATEA ARLTERLRRA AVDTFLESGY DGTTMEAVAQ AAGITKSTLY
ARYPDKRTLF IAVSSWALTR QERDERVLEP LPDDLAESLT VIARAILARS VDPDIVRLSR
MAIAESARFP EFAASSQAVT WSPRVQLIID LLRRHESAGT VVVGDVDLAA EQFFAMVGAM
PAWLAAYGIY RTPEVEEEHL HHAVSLFLNG VLARPETMPA PHPTEAARPA GEGPAVPRAS
WPMEYRRLGR SGLNVSRLAL GVAALGAGPA DHDERAAIGV IHRFLDAGGN LLDTTAAGDI
GRGGTDPDGA AAELCGRAVR DRRSSVVLAS SVGRPSGQGP HDGGNSRRHI RAACEATLRR
LRTDYLDLLQ LDADDPTTPL EETIDALDDL VRAGKVLYVG VANLHVYRVT KALSVSDRLG
RARFISFRGP YGLLSRELEH EHLPLLAEEG LGLISTSSLR SPGHGHGHGH ATVAATEAAA
AELGCTTTQL SLAWQLTRSV TSITLDVASA AQLDEHLAAL GIEIPTEIAA ALEQVSRPQG
//
