ID A8L683_FRASN Unreviewed; 723 AA.
AC A8L683;
DT 04-DEC-2007, integrated into UniProtKB/TrEMBL.
DT 04-DEC-2007, sequence version 1.
DT 27-MAR-2024, entry version 60.
DE SubName: Full=MmpL domain protein {ECO:0000313|EMBL:ABW16476.1};
GN ORFNames=Franean1_7157 {ECO:0000313|EMBL:ABW16476.1};
OS Frankia sp. (strain EAN1pec).
OC Bacteria; Actinomycetota; Actinomycetes; Frankiales; Frankiaceae; Frankia.
OX NCBI_TaxID=298653 {ECO:0000313|EMBL:ABW16476.1};
RN [1] {ECO:0000313|EMBL:ABW16476.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=EAN1.pec {ECO:0000313|EMBL:ABW16476.1};
RG US DOE Joint Genome Institute;
RA Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Hammon N.,
RA Israni S., Dalin E., Tice H., Pitluck S., Saunders E., Brettin T.,
RA Bruce D., Detter J.C., Han C., Schmutz J., Larimer F., Land M., Hauser L.,
RA Kyrpides N., Kim E., Rawnsley T., Niemann J., Benson D.R., Huang Y.,
RA Mastronunzio J., Bassi C.A., Tisa L.S., Richardson P.;
RT "Complete sequence of Frankia sp. EAN1pec.";
RL Submitted (AUG-2007) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; CP000820; ABW16476.1; -; Genomic_DNA.
DR AlphaFoldDB; A8L683; -.
DR STRING; 298653.Franean1_7157; -.
DR KEGG; fre:Franean1_7157; -.
DR eggNOG; COG2409; Bacteria.
DR HOGENOM; CLU_005108_1_1_11; -.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR Gene3D; 1.20.1640.10; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR InterPro; IPR004869; MMPL_dom.
DR InterPro; IPR000731; SSD.
DR PANTHER; PTHR33406; MEMBRANE PROTEIN MJ1562-RELATED; 1.
DR PANTHER; PTHR33406:SF2; MEMBRANE PROTEIN SCO6666-RELATED; 1.
DR Pfam; PF03176; MMPL; 2.
DR SUPFAM; SSF82866; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR PROSITE; PS50156; SSD; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 177..195
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 202..221
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 227..249
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 275..301
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 307..331
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 363..382
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 512..531
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 543..563
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 583..603
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 624..644
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 656..680
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 197..326
FT /note="SSD"
FT /evidence="ECO:0000259|PROSITE:PS50156"
SQ SEQUENCE 723 AA; 74886 MW; E2E253BC4AAF0091 CRC64;
MKQFTRRVGD AAARRPKLTI AVWGVVAALL LALAGTVGGP FADDLVAPGS QSENAMELLE
ERFPEAAGGS ALAVFAVAEG QRLERHRDAV SVAVARIEGV EHVATVTDPF TAGTVSPGGR
IGFAEITFDV PATEVGPEAL AAITDQLRPA RDAGLVAELG GDAAFINAEA ATSGTEMVGL
LAALVVLVVA FGTIVAALVP IVLALVTVAA GVGGVVLLAN AMDVSSAAPT IGAMIGLGVG
IDYAMFVVAR YRENRAAGQD DPTALSNAMG SSGTAVLLAG GTVVVAMLAL VLTGLGFLAS
IGLSTSLVVL FAVASALTLL PALLTLLGGR IDAGRVLGRR RAARHPRDTA WWRLAHRVSG
RPWPYLLVAA AALLVLAAPA LWMRTGFPDA GDDSTSTTHR RAYDLLAEGF GPGVNAPLLL
VADLRRPGAD LDTIRALAWH VAADTGIATV GDPQISPAGD TAVLHALPTT APADTATSET
LARIRDLVPG NVAVSGTTAL TDDLTRQLAD TLPIFIAAIL AASFLLLMVV FRSVVLPLKA
ALLNLLSIGG AYGVVVAVFQ WGWLGSLFRL EGTYLIASPL PTIFFAVLFG LSIDYEVFLL
SRIREEYDAT GDNAESVARG MAGTGRVITS AALIMTVVFL SFVANPSPLV RMMGLGLAAA
IVLDATIVRM VLVPATMALL GRANWWLPRW LDRRLPRVGS GDADLLRQCE PVPAVPADLV
KRG
//
