ID   A8LGF6_FRASN            Unreviewed;       844 AA.
AC   A8LGF6;
DT   04-DEC-2007, integrated into UniProtKB/TrEMBL.
DT   04-DEC-2007, sequence version 1.
DT   27-MAR-2024, entry version 68.
DE   RecName: Full=alpha-L-rhamnosidase {ECO:0000256|ARBA:ARBA00012652};
DE            EC=3.2.1.40 {ECO:0000256|ARBA:ARBA00012652};
GN   ORFNames=Franean1_0430 {ECO:0000313|EMBL:ABW09895.1};
OS   Frankia sp. (strain EAN1pec).
OC   Bacteria; Actinomycetota; Actinomycetes; Frankiales; Frankiaceae; Frankia.
OX   NCBI_TaxID=298653 {ECO:0000313|EMBL:ABW09895.1};
RN   [1] {ECO:0000313|EMBL:ABW09895.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=EAN1.pec {ECO:0000313|EMBL:ABW09895.1};
RG   US DOE Joint Genome Institute;
RA   Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Hammon N.,
RA   Israni S., Dalin E., Tice H., Pitluck S., Saunders E., Brettin T.,
RA   Bruce D., Detter J.C., Han C., Schmutz J., Larimer F., Land M., Hauser L.,
RA   Kyrpides N., Kim E., Rawnsley T., Niemann J., Benson D.R., Huang Y.,
RA   Mastronunzio J., Bassi C.A., Tisa L.S., Richardson P.;
RT   "Complete sequence of Frankia sp. EAN1pec.";
RL   Submitted (AUG-2007) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=Hydrolysis of terminal non-reducing alpha-L-rhamnose residues
CC         in alpha-L-rhamnosides.; EC=3.2.1.40;
CC         Evidence={ECO:0000256|ARBA:ARBA00001445};
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DR   EMBL; CP000820; ABW09895.1; -; Genomic_DNA.
DR   AlphaFoldDB; A8LGF6; -.
DR   STRING; 298653.Franean1_0430; -.
DR   CAZy; GH78; Glycoside Hydrolase Family 78.
DR   KEGG; fre:Franean1_0430; -.
DR   eggNOG; COG0174; Bacteria.
DR   HOGENOM; CLU_002926_0_0_11; -.
DR   GO; GO:0030596; F:alpha-L-rhamnosidase activity; IEA:UniProtKB-EC.
DR   GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR   Gene3D; 1.50.10.10; -; 1.
DR   Gene3D; 2.60.120.260; Galactose-binding domain-like; 2.
DR   Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR   Gene3D; 2.60.420.10; Maltose phosphorylase, domain 3; 1.
DR   InterPro; IPR008928; 6-hairpin_glycosidase_sf.
DR   InterPro; IPR012341; 6hp_glycosidase-like_sf.
DR   InterPro; IPR016007; Alpha_rhamnosid.
DR   InterPro; IPR035396; Bac_rhamnosid6H.
DR   InterPro; IPR035398; Bac_rhamnosid_C.
DR   InterPro; IPR013737; Bac_rhamnosid_N.
DR   InterPro; IPR013783; Ig-like_fold.
DR   InterPro; IPR008902; Rhamnosid_concanavalin.
DR   PANTHER; PTHR33307; ALPHA-RHAMNOSIDASE (EUROFUNG); 1.
DR   PANTHER; PTHR33307:SF6; ALPHA-RHAMNOSIDASE (EUROFUNG)-RELATED; 1.
DR   Pfam; PF05592; Bac_rhamnosid; 1.
DR   Pfam; PF17389; Bac_rhamnosid6H; 1.
DR   Pfam; PF17390; Bac_rhamnosid_C; 1.
DR   Pfam; PF08531; Bac_rhamnosid_N; 1.
DR   PIRSF; PIRSF010631; A-rhamnsds; 1.
DR   SUPFAM; SSF48208; Six-hairpin glycosidases; 1.
PE   4: Predicted;
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801}.
FT   DOMAIN          134..262
FT                   /note="Bacterial alpha-L-rhamnosidase N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF08531"
FT   DOMAIN          303..396
FT                   /note="Alpha-L-rhamnosidase concanavalin-like"
FT                   /evidence="ECO:0000259|Pfam:PF05592"
FT   DOMAIN          403..752
FT                   /note="Alpha-L-rhamnosidase six-hairpin glycosidase"
FT                   /evidence="ECO:0000259|Pfam:PF17389"
FT   DOMAIN          754..827
FT                   /note="Alpha-L-rhamnosidase C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF17390"
SQ   SEQUENCE   844 AA;  92776 MW;  DB40ED353CBA5927 CRC64;
     MVQPCAPRFE HRTEPGPVLG LGAPAPRLSW TVTRAEEGWR QTAYEVQVAG KVFTVRSAEQ
     VLVPWPARPL RSRERAEVKV RVAYGDHWSP WSEAATVEAG LLDAADWTAR FISPVDPGER
     APVVVGHVEV PGPVRSARLY ATAHGIYVPS INGRRVDDTV LAPGWTSYEH RLRYHVYDVT
     TLIRPGENVL EFVLGNGWYR GRLGWTNQRA IYGDRLALLA QLEITTFDGA VRVLATDGTW
     HARPSEVLAD DLYDGQTTDL RPHDAPATGV DIVEGDLTRL VAPDGPPIRP TSVLPARKVW
     TSPAGKTLVD FGQNAVGWIR LRVRDLPAGT TVVVRHAEVL EDKELGTRPL RSARATDTWV
     LSGHDEVLEP SLTLHGFRYA EVTGVPDLRE QDIALVVVGS DLRRTGWFSS SHEQLNQLHE
     NVVWSTRGNF VDLPTDCPQR DERLGWTGDI QIFGPTATFL YDTAGLLRSW LADLAAEQRP
     DGSVPHVVPE IDRAPEFRTP AAAWGDAATV VPWTLYQRTG DLQMLERQLP SMSAWVDKVA
     ALAGPDRLWR GGFQFGDWLD PTAPPENPGR AKADPDVVAT AHFARSSWIV AESARLLGRA
     ADAEKYRTLT DEVRAAFVRA FVTPQGRIHS DAQTLYALAI EWDLLPEAEQ RVAAGHRLAE
     LVRDGGFHIA TGFVGTPLVC DALTSTGHLD VAYRLLLQTQ CPSWLYPVTM GATTVWERWD
     SMRPDGTINP GEMTSFNHYA LGAVADWLHR TVAGLAPAAP GYRRLLVHPR LTPELTGAAA
     THLTPYGKAS VSWLRSAGHL RLDVHVPVGA SAEVHVPGAE QPVTVGHGDH RWLVADPVSR
     SEGR
//