ID A8M834_SALAI Unreviewed; 451 AA.
AC A8M834;
DT 04-DEC-2007, integrated into UniProtKB/TrEMBL.
DT 04-DEC-2007, sequence version 1.
DT 27-MAR-2024, entry version 79.
DE SubName: Full=3'-5' exonuclease {ECO:0000313|EMBL:ABV97368.1};
GN OrderedLocusNames=Sare_1470 {ECO:0000313|EMBL:ABV97368.1};
OS Salinispora arenicola (strain CNS-205).
OC Bacteria; Actinomycetota; Actinomycetes; Micromonosporales;
OC Micromonosporaceae; Salinispora.
OX NCBI_TaxID=391037 {ECO:0000313|EMBL:ABV97368.1};
RN [1] {ECO:0000313|EMBL:ABV97368.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CNS-205 {ECO:0000313|EMBL:ABV97368.1};
RG US DOE Joint Genome Institute;
RA Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E.,
RA Tice H., Pitluck S., Foster B., Schmutz J., Larimer F., Land M., Hauser L.,
RA Kyrpides N., Ivanova N., Jensen P.R., Moore B.S., Penn K., Jenkins C.,
RA Udwary D., Xiang L., Gontang E., Richardson P.;
RT "Complete sequence of Salinispora arenicola CNS-205.";
RL Submitted (OCT-2007) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; CP000850; ABV97368.1; -; Genomic_DNA.
DR AlphaFoldDB; A8M834; -.
DR STRING; 391037.Sare_1470; -.
DR KEGG; saq:Sare_1470; -.
DR PATRIC; fig|391037.6.peg.1495; -.
DR eggNOG; COG0349; Bacteria.
DR HOGENOM; CLU_042387_3_0_11; -.
DR OrthoDB; 144122at2; -.
DR GO; GO:0008408; F:3'-5' exonuclease activity; IEA:InterPro.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR GO; GO:0006139; P:nucleobase-containing compound metabolic process; IEA:InterPro.
DR CDD; cd06142; RNaseD_exo; 1.
DR Gene3D; 1.10.150.80; HRDC domain; 2.
DR Gene3D; 3.30.420.10; Ribonuclease H-like superfamily/Ribonuclease H; 1.
DR InterPro; IPR002562; 3'-5'_exonuclease_dom.
DR InterPro; IPR041605; Exo_C.
DR InterPro; IPR010997; HRDC-like_sf.
DR InterPro; IPR002121; HRDC_dom.
DR InterPro; IPR044876; HRDC_dom_sf.
DR InterPro; IPR012337; RNaseH-like_sf.
DR InterPro; IPR036397; RNaseH_sf.
DR PANTHER; PTHR47649; RIBONUCLEASE D; 1.
DR PANTHER; PTHR47649:SF1; RIBONUCLEASE D; 1.
DR Pfam; PF01612; DNA_pol_A_exo1; 1.
DR Pfam; PF18305; DNA_pol_A_exoN; 1.
DR Pfam; PF00570; HRDC; 1.
DR SMART; SM00474; 35EXOc; 1.
DR SMART; SM00341; HRDC; 1.
DR SUPFAM; SSF47819; HRDC-like; 1.
DR SUPFAM; SSF53098; Ribonuclease H-like; 1.
DR PROSITE; PS50967; HRDC; 1.
PE 4: Predicted;
KW Exonuclease {ECO:0000313|EMBL:ABV97368.1};
KW Hydrolase {ECO:0000313|EMBL:ABV97368.1};
KW Nuclease {ECO:0000313|EMBL:ABV97368.1}.
FT DOMAIN 268..348
FT /note="HRDC"
FT /evidence="ECO:0000259|PROSITE:PS50967"
FT REGION 1..66
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..15
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 451 AA; 48520 MW; D24195E756A54775 CRC64;
MTDEPPLRRR AAANRTGDTP HPPLIRSGGV GVDPTTGGPP SIGSEADAGP APLTTPSEGT
PQPVTTPTEL AGVVARFSAG TGPVALDAER ASGYRYSQRA YLVQLRRAGA GTALIDPLPL
PELTTLDEAI GEAEWVLHAA SQDLPCLAEL GLRPRRLFDT ELAARLAGFE RVGLAALTEH
LLGFSLEKHH SAADWSSRPL PESWLTYAAL DVELLVELRD ALEAELTRQG KAEWAAEEFA
ALVRNGARPP RVRAEPWRRT SGIHRVRGAR AQARVRSLWY ARDQIAARRD AAPGRVLPDS
AIVAAAELDP RDEKTLLTLP GFGGRSVRRL ARTWLAALDD ARTLPEDALP VAPTVEGPPP
PHRWAERDPV AAARLARCRE VVVGIAGTHS LPPENLIAPD SVRRLAWVPP EEITDVTVAE
TLRGLGAREW QITLLQPDLT RALGDAPTAR A
//
