ID   A8MEJ2_ALKOO            Unreviewed;       496 AA.
AC   A8MEJ2;
DT   04-DEC-2007, integrated into UniProtKB/TrEMBL.
DT   04-DEC-2007, sequence version 1.
DT   27-MAR-2024, entry version 88.
DE   SubName: Full=Putative transcriptional regulator, GntR family {ECO:0000313|EMBL:ABW18321.1};
GN   OrderedLocusNames=Clos_0769 {ECO:0000313|EMBL:ABW18321.1};
OS   Alkaliphilus oremlandii (strain OhILAs) (Clostridium oremlandii (strain
OS   OhILAs)).
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae;
OC   Alkaliphilus.
OX   NCBI_TaxID=350688 {ECO:0000313|EMBL:ABW18321.1, ECO:0000313|Proteomes:UP000000269};
RN   [1] {ECO:0000313|Proteomes:UP000000269}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=OhILAs {ECO:0000313|Proteomes:UP000000269};
RA   Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C.,
RA   Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S.,
RA   Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M.,
RA   Hauser L., Kyrpides N., Mikhailova N., Stolz J.F., Dawson A., Fisher E.,
RA   Crable B., Perera E., Lisak J., Ranganathan M., Basu P., Richardson P.;
RT   "Complete genome of Alkaliphilus oremlandii OhILAs.";
RL   Submitted (OCT-2007) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: In the C-terminal section; belongs to the class-I
CC       pyridoxal-phosphate-dependent aminotransferase family.
CC       {ECO:0000256|ARBA:ARBA00005384}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CP000853; ABW18321.1; -; Genomic_DNA.
DR   RefSeq; WP_012158633.1; NC_009922.1.
DR   AlphaFoldDB; A8MEJ2; -.
DR   STRING; 350688.Clos_0769; -.
DR   KEGG; aoe:Clos_0769; -.
DR   eggNOG; COG1167; Bacteria.
DR   HOGENOM; CLU_017584_0_1_9; -.
DR   OrthoDB; 9808770at2; -.
DR   Proteomes; UP000000269; Chromosome.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
DR   GO; GO:0009058; P:biosynthetic process; IEA:InterPro.
DR   CDD; cd00609; AAT_like; 1.
DR   CDD; cd07377; WHTH_GntR; 1.
DR   Gene3D; 3.40.640.10; Type I PLP-dependent aspartate aminotransferase-like (Major domain); 1.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR   InterPro; IPR004839; Aminotransferase_I/II.
DR   InterPro; IPR015424; PyrdxlP-dep_Trfase.
DR   InterPro; IPR015421; PyrdxlP-dep_Trfase_major.
DR   InterPro; IPR000524; Tscrpt_reg_HTH_GntR.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   PANTHER; PTHR46577; HTH-TYPE TRANSCRIPTIONAL REGULATORY PROTEIN GABR; 1.
DR   PANTHER; PTHR46577:SF1; HTH-TYPE TRANSCRIPTIONAL REGULATORY PROTEIN GABR; 1.
DR   Pfam; PF00155; Aminotran_1_2; 1.
DR   Pfam; PF00392; GntR; 1.
DR   SMART; SM00345; HTH_GNTR; 1.
DR   SUPFAM; SSF53383; PLP-dependent transferases; 1.
DR   SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR   PROSITE; PS50949; HTH_GNTR; 1.
PE   3: Inferred from homology;
KW   DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW   Pyridoxal phosphate {ECO:0000256|ARBA:ARBA00022898};
KW   Reference proteome {ECO:0000313|Proteomes:UP000000269};
KW   Transcription {ECO:0000256|ARBA:ARBA00023163};
KW   Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT   DOMAIN          10..78
FT                   /note="HTH gntR-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50949"
SQ   SEQUENCE   496 AA;  57278 MW;  CB58715BA1F07611 CRC64;
     MIYINEKSEI PIYQQIYAQI KEDIIGGALV EGDKLASTRV LAKELCVSRN TVENSYSQLS
     LEGYVESIPG SGFIVKNINE ELFFHPSKIS DKLRSTIEAY DRESALLNDD SLFYKYNFQY
     GSFDDSIFPY SLWRRLTAQA LLSIDSKKIN FYNDKQGELD LRIEIMNYLK GFRGVSCTPE
     QIVICSGNQH ALDLICKIFS KYSPKIAIEE PGYDGARIVF ENNNFEINPI PVQSDGINIV
     ELEKSSAKLV YITPSHQFPT GVIMPIQNRI HLLHWATQND GVIIEDDYDS EFRYHSRPIP
     SLQSIDQNER VIYLGTFSKA LSPGLRMSYM ILPKWLLSKY NELFNGYYPT VPWLQQKILS
     LYMSSGHWER YLRKARLSYK RKHDILVQTL TNLMGDQVII HGNNAGLHIV LEFVNGEHED
     WLIEIAKAHK IKVYPISPFW YIKESYSNNM ILLGFSMLNE EEIIEAITLL EKAWFHHFGN
     PFDGDSNVSV YCHYCK
//