ID A8MVA8_HUMAN Unreviewed; 129 AA.
AC A8MVA8;
DT 04-DEC-2007, integrated into UniProtKB/TrEMBL.
DT 04-DEC-2007, sequence version 1.
DT 27-MAR-2024, entry version 94.
DE SubName: Full=Discs large MAGUK scaffold protein 2 {ECO:0000313|Ensembl:ENSP00000381349.1};
GN Name=DLG2 {ECO:0000313|Ensembl:ENSP00000381349.1};
OS Homo sapiens (Human).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Homo.
OX NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000381349.1, ECO:0000313|Proteomes:UP000005640};
RN [1] {ECO:0000313|Ensembl:ENSP00000381349.1, ECO:0000313|Proteomes:UP000005640}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=16554811; DOI=10.1038/nature04632;
RA Taylor T.D., Noguchi H., Totoki Y., Toyoda A., Kuroki Y., Dewar K.,
RA Lloyd C., Itoh T., Takeda T., Kim D.W., She X., Barlow K.F., Bloom T.,
RA Bruford E., Chang J.L., Cuomo C.A., Eichler E., FitzGerald M.G.,
RA Jaffe D.B., LaButti K., Nicol R., Park H.S., Seaman C., Sougnez C.,
RA Yang X., Zimmer A.R., Zody M.C., Birren B.W., Nusbaum C., Fujiyama A.,
RA Hattori M., Rogers J., Lander E.S., Sakaki Y.;
RT "Human chromosome 11 DNA sequence and analysis including novel gene
RT identification.";
RL Nature 440:497-500(2006).
RN [2] {ECO:0000313|Ensembl:ENSP00000381349.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; AP000773; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AP003026; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; KC877445; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; KC877447; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; KC877450; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; KF455429; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; A8MVA8; -.
DR SMR; A8MVA8; -.
DR MassIVE; A8MVA8; -.
DR PeptideAtlas; A8MVA8; -.
DR ProteomicsDB; 2166; -.
DR Antibodypedia; 8247; 429 antibodies from 35 providers.
DR Ensembl; ENST00000398304.5; ENSP00000381349.1; ENSG00000150672.19.
DR UCSC; uc058gcc.1; human.
DR HGNC; HGNC:2901; DLG2.
DR VEuPathDB; HostDB:ENSG00000150672; -.
DR GeneTree; ENSGT00940000155156; -.
DR ChiTaRS; DLG2; human.
DR Proteomes; UP000005640; Chromosome 11.
DR Bgee; ENSG00000150672; Expressed in cortical plate and 135 other cell types or tissues.
DR ExpressionAtlas; A8MVA8; baseline and differential.
DR Gene3D; 2.30.30.40; SH3 Domains; 1.
DR InterPro; IPR036028; SH3-like_dom_sf.
DR InterPro; IPR001452; SH3_domain.
DR PANTHER; PTHR23119; DISCS LARGE; 1.
DR PANTHER; PTHR23119:SF6; DISKS LARGE HOMOLOG 2; 1.
DR Pfam; PF00018; SH3_1; 1.
DR SMART; SM00326; SH3; 1.
DR SUPFAM; SSF50044; SH3-domain; 1.
DR PROSITE; PS50002; SH3; 1.
PE 1: Evidence at protein level;
KW Proteomics identification {ECO:0007829|EPD:A8MVA8,
KW ECO:0007829|MaxQB:A8MVA8};
KW Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW SH3 domain {ECO:0000256|ARBA:ARBA00022443, ECO:0000256|PROSITE-
KW ProRule:PRU00192}.
FT DOMAIN 18..88
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
SQ SEQUENCE 129 AA; 14512 MW; B4754F8446E7A0E9 CRC64;
MMNHSMSSGS GSLRTNQKRS LYVRAMFDYD KSKDSGLPSQ GLSFKYGDIL HVINASDDEW
WQARRVMLEG DSEEMGVIPS KRRVERKERA RLKTVKFNAK PGVIDSKGDI PGLGDDGYGT
KTLNTFFIC
//
