ID A8N2S0_COPC7 Unreviewed; 460 AA.
AC A8N2S0;
DT 15-JAN-2008, integrated into UniProtKB/TrEMBL.
DT 15-JAN-2008, sequence version 1.
DT 27-MAR-2024, entry version 72.
DE RecName: Full=Sorting nexin-4 {ECO:0000256|ARBA:ARBA00040748};
DE AltName: Full=Autophagy-related protein 24 {ECO:0000256|ARBA:ARBA00041273};
GN ORFNames=CC1G_01822 {ECO:0000313|EMBL:EAU92777.1};
OS Coprinopsis cinerea (strain Okayama-7 / 130 / ATCC MYA-4618 / FGSC 9003)
OS (Inky cap fungus) (Hormographiella aspergillata).
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC Agaricomycetidae; Agaricales; Agaricineae; Psathyrellaceae; Coprinopsis.
OX NCBI_TaxID=240176 {ECO:0000313|EMBL:EAU92777.1, ECO:0000313|Proteomes:UP000001861};
RN [1] {ECO:0000313|EMBL:EAU92777.1, ECO:0000313|Proteomes:UP000001861}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Okayama-7 / 130 / ATCC MYA-4618 / FGSC 9003
RC {ECO:0000313|Proteomes:UP000001861};
RX PubMed=20547848; DOI=10.1073/pnas.1003391107;
RA Stajich J.E., Wilke S.K., Ahren D., Au C.H., Birren B.W., Borodovsky M.,
RA Burns C., Canback B., Casselton L.A., Cheng C.K., Deng J., Dietrich F.S.,
RA Fargo D.C., Farman M.L., Gathman A.C., Goldberg J., Guigo R., Hoegger P.J.,
RA Hooker J.B., Huggins A., James T.Y., Kamada T., Kilaru S., Kodira C.,
RA Kues U., Kupfer D., Kwan H.S., Lomsadze A., Li W., Lilly W.W., Ma L.J.,
RA Mackey A.J., Manning G., Martin F., Muraguchi H., Natvig D.O.,
RA Palmerini H., Ramesh M.A., Rehmeyer C.J., Roe B.A., Shenoy N., Stanke M.,
RA Ter-Hovhannisyan V., Tunlid A., Velagapudi R., Vision T.J., Zeng Q.,
RA Zolan M.E., Pukkila P.J.;
RT "Insights into evolution of multicellular fungi from the assembled
RT chromosomes of the mushroom Coprinopsis cinerea (Coprinus cinereus).";
RL Proc. Natl. Acad. Sci. U.S.A. 107:11889-11894(2010).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EAU92777.1}.
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DR EMBL; AACS02000001; EAU92777.1; -; Genomic_DNA.
DR RefSeq; XP_001829142.1; XM_001829090.1.
DR AlphaFoldDB; A8N2S0; -.
DR STRING; 240176.A8N2S0; -.
DR GeneID; 6005568; -.
DR KEGG; cci:CC1G_01822; -.
DR VEuPathDB; FungiDB:CC1G_01822; -.
DR eggNOG; KOG2273; Eukaryota.
DR InParanoid; A8N2S0; -.
DR OMA; WSLHRFI; -.
DR OrthoDB; 51972at2759; -.
DR Proteomes; UP000001861; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.
DR CDD; cd07628; BAR_Atg24p; 1.
DR CDD; cd06863; PX_Atg24p; 1.
DR Gene3D; 1.20.1270.60; Arfaptin homology (AH) domain/BAR domain; 1.
DR Gene3D; 3.30.1520.10; Phox-like domain; 1.
DR InterPro; IPR027267; AH/BAR_dom_sf.
DR InterPro; IPR001683; PX_dom.
DR InterPro; IPR036871; PX_dom_sf.
DR PANTHER; PTHR45949; SORTING NEXIN-4; 1.
DR PANTHER; PTHR45949:SF2; SORTING NEXIN-4; 1.
DR Pfam; PF00787; PX; 1.
DR SMART; SM00312; PX; 1.
DR SUPFAM; SSF103657; BAR/IMD domain-like; 1.
DR SUPFAM; SSF64268; PX domain; 1.
DR PROSITE; PS50195; PX; 1.
PE 4: Predicted;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Lipid-binding {ECO:0000256|ARBA:ARBA00023121};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Reference proteome {ECO:0000313|Proteomes:UP000001861}.
FT DOMAIN 54..176
FT /note="PX"
FT /evidence="ECO:0000259|PROSITE:PS50195"
FT REGION 1..47
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 460 AA; 52573 MW; C4DB758DAE719ED3 CRC64;
MLNDDEDVFD SVTWESPSAT GYDNHDENAA IGPGFRQSTA DGNDDPLQPK WEGYLITSVR
DPVKELAETK DAYVSYLVSA KTNLPIFSTP NPSSRRRFQD FVFLKENLSR DFPACVVPAL
PDKHRLEYIT GDRFSPEFME RRRVDLHRFL QRIARHPILQ RSTLVRAFFE STEWHVYMHQ
HIAHPPTQEP APGLIDNLSD TLLNAFSRVR KPDERFLVMR ENVDKFEEGL TSMERLYTRL
RNRTSDLTAD YHDLAVAVQG LGFLESGITD PLNHFSNTLL EFSALLRHLT QTTTDPLLVH
LHSLLTYSHA NRAVLKLRDQ KQLDLEELTD YLSGVTAERD RLSAIISGHA GSSGLGIGAY
IKDRVDALRG ADDDRSRVEK MKKLDSKIKE LQDAVTTAHE TSDAFNDATL REQTIFQYAK
QEELKETLGE LADGQIEFYK AAMEEWDRII PIIQRIRVDV
//
