GenomeNet

Database: UniProt
Entry: A8PQY6_MALGO
LinkDB: A8PQY6_MALGO
Original site: A8PQY6_MALGO 
ID   A8PQY6_MALGO            Unreviewed;       855 AA.
AC   A8PQY6;
DT   15-JAN-2008, integrated into UniProtKB/TrEMBL.
DT   15-JAN-2008, sequence version 1.
DT   07-JUN-2017, entry version 39.
DE   RecName: Full=V-type proton ATPase subunit a {ECO:0000256|RuleBase:RU361189};
GN   ORFNames=MGL_0542 {ECO:0000313|EMBL:EDP45553.1};
OS   Malassezia globosa (strain ATCC MYA-4612 / CBS 7966)
OS   (Dandruff-associated fungus).
OC   Eukaryota; Fungi; Dikarya; Basidiomycota; Ustilaginomycotina;
OC   Malasseziomycetes; Malasseziales; Malasseziaceae; Malassezia.
OX   NCBI_TaxID=425265 {ECO:0000313|EMBL:EDP45553.1, ECO:0000313|Proteomes:UP000008837};
RN   [1] {ECO:0000313|EMBL:EDP45553.1, ECO:0000313|Proteomes:UP000008837}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC MYA-4612 / CBS 7966 {ECO:0000313|Proteomes:UP000008837};
RX   PubMed=18000048; DOI=10.1073/pnas.0706756104;
RA   Xu J., Saunders C.W., Hu P., Grant R.A., Boekhout T., Kuramae E.E.,
RA   Kronstad J.W., Deangelis Y.M., Reeder N.L., Johnstone K.R., Leland M.,
RA   Fieno A.M., Begley W.M., Sun Y., Lacey M.P., Chaudhary T., Keough T.,
RA   Chu L., Sears R., Yuan B., Dawson T.L.Jr.;
RT   "Dandruff-associated Malassezia genomes reveal convergent and
RT   divergent virulence traits shared with plant and human fungal
RT   pathogens.";
RL   Proc. Natl. Acad. Sci. U.S.A. 104:18730-18735(2007).
CC   -!- FUNCTION: Essential component of the vacuolar proton pump (V-
CC       ATPase), a multimeric enzyme that catalyzes the translocation of
CC       protons across the membranes. Required for assembly and activity
CC       of the V-ATPase. {ECO:0000256|RuleBase:RU361189}.
CC   -!- SIMILARITY: Belongs to the V-ATPase 116 kDa subunit family.
CC       {ECO:0000256|RuleBase:RU361189}.
CC   -!- CAUTION: The sequence shown here is derived from an
CC       EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is
CC       preliminary data. {ECO:0000313|EMBL:EDP45553.1}.
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution-NoDerivs License
CC   -----------------------------------------------------------------------
DR   EMBL; AAYY01000001; EDP45553.1; -; Genomic_DNA.
DR   RefSeq; XP_001732767.1; XM_001732715.1.
DR   STRING; 425265.XP_001732767.1; -.
DR   GeneID; 5857073; -.
DR   KEGG; mgl:MGL_0542; -.
DR   EuPathDB; FungiDB:MGL_0542; -.
DR   eggNOG; KOG2189; Eukaryota.
DR   eggNOG; COG1269; LUCA.
DR   InParanoid; A8PQY6; -.
DR   KO; K02154; -.
DR   OrthoDB; EOG092C0YCY; -.
DR   Proteomes; UP000008837; Unassembled WGS sequence.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0000220; C:vacuolar proton-transporting V-type ATPase, V0 domain; IEA:InterPro.
DR   GO; GO:0015078; F:hydrogen ion transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0015991; P:ATP hydrolysis coupled proton transport; IEA:InterPro.
DR   InterPro; IPR002490; V-ATPase_116kDa_su.
DR   InterPro; IPR026028; V-type_ATPase_116kDa_su_euka.
DR   PANTHER; PTHR11629; PTHR11629; 1.
DR   Pfam; PF01496; V_ATPase_I; 1.
DR   PIRSF; PIRSF001293; ATP6V0A1; 1.
PE   3: Inferred from homology;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Complete proteome {ECO:0000313|Proteomes:UP000008837};
KW   Hydrogen ion transport {ECO:0000256|RuleBase:RU361189};
KW   Ion transport {ECO:0000256|RuleBase:RU361189};
KW   Membrane {ECO:0000256|RuleBase:RU361189};
KW   Reference proteome {ECO:0000313|Proteomes:UP000008837};
KW   Transmembrane {ECO:0000256|RuleBase:RU361189};
KW   Transmembrane helix {ECO:0000256|RuleBase:RU361189};
KW   Transport {ECO:0000256|RuleBase:RU361189}.
FT   TRANSMEM    434    459       Helical. {ECO:0000256|RuleBase:RU361189}.
FT   TRANSMEM    480    497       Helical. {ECO:0000256|RuleBase:RU361189}.
FT   TRANSMEM    552    571       Helical. {ECO:0000256|RuleBase:RU361189}.
FT   TRANSMEM    583    607       Helical. {ECO:0000256|RuleBase:RU361189}.
FT   TRANSMEM    660    679       Helical. {ECO:0000256|RuleBase:RU361189}.
FT   TRANSMEM    802    826       Helical. {ECO:0000256|RuleBase:RU361189}.
FT   COILED      104    145       {ECO:0000256|SAM:Coils}.
SQ   SEQUENCE   855 AA;  96587 MW;  7C3F1B6E5F229767 CRC64;
     MSEEEGLFRS ASMSLIQLYI PSESVHATVT ELGELGNVQF RDLNPDVTPF QRTFVADIRR
     LDEMDRRIQF LQAQLEREAI PARALESAIP FLTADDGMNG PLRLEELARR LQEHETRVTQ
     MNHSHDALQK RLLELEEAKN VIRETEVFFQ HAESPPAAAS DADHVRVSMD EEGREDEAHA
     PLLTSQGSGV RNMGAIAPVD LEFVAGTIER TQMATLERVL WRALRGNLYM NYAEIQQAFE
     DPARDEPVFK NVFVIFAHGS TILSKIRRIC ESMGGTLYPV ASDPTQCREN LHQVLERIED
     HENILYSTNA TRRTELVRVA ESIEAWQDLV RREKLVYSTM NLFQTEVNQK TLVAEGWAPT
     TELATVQLAL RRATESTGAH VSSVMQTMQT KETPPTFQRT NKVTEGFQAI IDAYGHARYQ
     EVNPGLFTVV TFPFLFAVMF GDVGHGVLMS LMAGAMVLYE RKLQRTRLDE ISSMFFYGRY
     IILFMGIASI FTGLIYNDIF SRSMHLFHSG WEWPRANGTL TAEPNGRVYP IGLDPSWHGA
     ENNLVFTNSF KMKLSIVLGV AHMTFALLLN VPNHLHFKRP TWIWAELVPQ MLFLEALFGY
     LVITIIYKWS TDWYAKDANG NNLHNSPPGL LNMLIYMFLK PGAVDPEQQL YAGQASVQSL
     LLLVAMVCVP WMLVAKPYLL YREHKHREGA GYHTVGSSRG EQRVNDVDEA ERELESDFID
     GGADGDDGES EEEFELGEVV IHQIIHTIEF CLGCISNTAS YLRLWALSLA HAQLSQVLWD
     MTIKTVFGMT GVLGVFATVF AFALWFVLTI AILCVMEGLS AFLHALRLHW VEGGSKHYMA
     DGYPFEPLTF APQDS
//
DBGET integrated database retrieval system