ID A8PVE6_MALGO Unreviewed; 778 AA.
AC A8PVE6;
DT 15-JAN-2008, integrated into UniProtKB/TrEMBL.
DT 15-JAN-2008, sequence version 1.
DT 27-MAR-2024, entry version 57.
DE RecName: Full=5-oxoprolinase {ECO:0008006|Google:ProtNLM};
GN ORFNames=MGL_0841 {ECO:0000313|EMBL:EDP44359.1};
OS Malassezia globosa (strain ATCC MYA-4612 / CBS 7966) (Dandruff-associated
OS fungus).
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Ustilaginomycotina;
OC Malasseziomycetes; Malasseziales; Malasseziaceae; Malassezia.
OX NCBI_TaxID=425265 {ECO:0000313|EMBL:EDP44359.1, ECO:0000313|Proteomes:UP000008837};
RN [1] {ECO:0000313|EMBL:EDP44359.1, ECO:0000313|Proteomes:UP000008837}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC MYA-4612 / CBS 7966 {ECO:0000313|Proteomes:UP000008837};
RX PubMed=18000048; DOI=10.1073/pnas.0706756104;
RA Xu J., Saunders C.W., Hu P., Grant R.A., Boekhout T., Kuramae E.E.,
RA Kronstad J.W., Deangelis Y.M., Reeder N.L., Johnstone K.R., Leland M.,
RA Fieno A.M., Begley W.M., Sun Y., Lacey M.P., Chaudhary T., Keough T.,
RA Chu L., Sears R., Yuan B., Dawson T.L.Jr.;
RT "Dandruff-associated Malassezia genomes reveal convergent and divergent
RT virulence traits shared with plant and human fungal pathogens.";
RL Proc. Natl. Acad. Sci. U.S.A. 104:18730-18735(2007).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EDP44359.1}.
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DR EMBL; AAYY01000003; EDP44359.1; -; Genomic_DNA.
DR RefSeq; XP_001731573.1; XM_001731521.1.
DR AlphaFoldDB; A8PVE6; -.
DR STRING; 425265.A8PVE6; -.
DR GeneID; 5855879; -.
DR KEGG; mgl:MGL_0841; -.
DR VEuPathDB; FungiDB:MGL_0841; -.
DR InParanoid; A8PVE6; -.
DR OMA; HAMTVSV; -.
DR OrthoDB; 674at2759; -.
DR Proteomes; UP000008837; Unassembled WGS sequence.
DR GO; GO:0016787; F:hydrolase activity; IEA:InterPro.
DR InterPro; IPR049517; ACX-like_C.
DR InterPro; IPR008040; Hydant_A_N.
DR InterPro; IPR002821; Hydantoinase_A.
DR InterPro; IPR045079; Oxoprolinase_fam.
DR PANTHER; PTHR11365:SF2; 5-OXOPROLINASE; 1.
DR PANTHER; PTHR11365; 5-OXOPROLINASE RELATED; 1.
DR Pfam; PF19278; Hydant_A_C; 1.
DR Pfam; PF05378; Hydant_A_N; 1.
DR Pfam; PF01968; Hydantoinase_A; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000008837}.
FT DOMAIN 7..254
FT /note="Hydantoinase/oxoprolinase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF05378"
FT DOMAIN 273..568
FT /note="Hydantoinase A/oxoprolinase"
FT /evidence="ECO:0000259|Pfam:PF01968"
FT DOMAIN 589..765
FT /note="Acetophenone carboxylase-like C-terminal"
FT /evidence="ECO:0000259|Pfam:PF19278"
SQ SEQUENCE 778 AA; 85622 MW; C59A54EBC2AEED5D CRC64;
MSLGIQIAID RGGTFTDCLG RIPASGDRPE RDIVIKLLSR DPNNYRDAPT EGIRRILEMA
SGRSIPRSEK ISTQDIAYIR LSTTVATNAL LERDGQRHAL ITTRGFRDIV QIGNQSRPAI
FDLAIHKPEV LYDQVVEVDE RVTVVGYSSD PHAREHSVQF SSMGRDARIT KPYTGKDKLP
SASPLNMPYK EPDIVRGISG EAVAILQKPD EARVRQDLER LYAEGYRSLA VVFMFSYTYP
EHEQLVKRIA QEIGFPSISC SAELMPMIKM VPRATSATAD AYLTPVLQAY IDGFFSGFDS
SLRDGRAGTR VEFMMSDGGL TSVEHFSGLK SIISGPAGGV VGMALTTYDK DDGRPCIGFD
MGGTSTDVSR YAGKYEQVME TTIDGVTIQS PQLDVNTVAS GGSSRLFFRN GLFVVGPESA
SAHPGPTCYR KGGPLAITDA NLVTGRLAME MFPRIFGPDE NEGLDVDAST RAFEELTERI
NRETGRTMSV DEVAQGFIRV ANEAMCRPIR SLTQARGYST SKHVLACFGG AGGQHACSIA
RALGITTVVV HKYSSILSAY GMALADRVFE VQEPCNETWE TTSSFDTSTA LGRIHTRAQN
LTKHAEDELH RQGFARDRIH TDTYLHMRYD GTDTALMTLK PADTWDMESV FVNNYRQEFG
FVLADRAILV DDIRVRAVGR TFDSLGPSVL AEHATQCAKS ETPFPKAKAL DTASFRPVYF
DGQGRVRTAI VRLRNLAIFE SVPGPAILID ETQTILVEPR CEAYILSQAV LIRVQYDE
//
