ID   A8QDH4_MALGO            Unreviewed;       992 AA.
AC   A8QDH4;
DT   15-JAN-2008, integrated into UniProtKB/TrEMBL.
DT   15-JAN-2008, sequence version 1.
DT   27-MAR-2024, entry version 69.
DE   RecName: Full=Importin N-terminal domain-containing protein {ECO:0000259|PROSITE:PS50166};
GN   ORFNames=MGL_4206 {ECO:0000313|EMBL:EDP41431.1};
OS   Malassezia globosa (strain ATCC MYA-4612 / CBS 7966) (Dandruff-associated
OS   fungus).
OC   Eukaryota; Fungi; Dikarya; Basidiomycota; Ustilaginomycotina;
OC   Malasseziomycetes; Malasseziales; Malasseziaceae; Malassezia.
OX   NCBI_TaxID=425265 {ECO:0000313|EMBL:EDP41431.1, ECO:0000313|Proteomes:UP000008837};
RN   [1] {ECO:0000313|EMBL:EDP41431.1, ECO:0000313|Proteomes:UP000008837}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC MYA-4612 / CBS 7966 {ECO:0000313|Proteomes:UP000008837};
RX   PubMed=18000048; DOI=10.1073/pnas.0706756104;
RA   Xu J., Saunders C.W., Hu P., Grant R.A., Boekhout T., Kuramae E.E.,
RA   Kronstad J.W., Deangelis Y.M., Reeder N.L., Johnstone K.R., Leland M.,
RA   Fieno A.M., Begley W.M., Sun Y., Lacey M.P., Chaudhary T., Keough T.,
RA   Chu L., Sears R., Yuan B., Dawson T.L.Jr.;
RT   "Dandruff-associated Malassezia genomes reveal convergent and divergent
RT   virulence traits shared with plant and human fungal pathogens.";
RL   Proc. Natl. Acad. Sci. U.S.A. 104:18730-18735(2007).
CC   -!- SIMILARITY: Belongs to the XPO2/CSE1 family.
CC       {ECO:0000256|ARBA:ARBA00008669}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EDP41431.1}.
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DR   EMBL; AAYY01000022; EDP41431.1; -; Genomic_DNA.
DR   RefSeq; XP_001728645.1; XM_001728593.1.
DR   AlphaFoldDB; A8QDH4; -.
DR   STRING; 425265.A8QDH4; -.
DR   GeneID; 5852959; -.
DR   KEGG; mgl:MGL_4206; -.
DR   VEuPathDB; FungiDB:MGL_4206; -.
DR   InParanoid; A8QDH4; -.
DR   OMA; AENEFLM; -.
DR   OrthoDB; 178772at2759; -.
DR   Proteomes; UP000008837; Unassembled WGS sequence.
DR   GO; GO:0005634; C:nucleus; IEA:UniProt.
DR   GO; GO:0031267; F:small GTPase binding; IEA:InterPro.
DR   GO; GO:0006886; P:intracellular protein transport; IEA:InterPro.
DR   Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR   InterPro; IPR011989; ARM-like.
DR   InterPro; IPR016024; ARM-type_fold.
DR   InterPro; IPR001494; Importin-beta_N.
DR   InterPro; IPR005043; XPO2_C.
DR   InterPro; IPR013713; XPO2_central.
DR   PANTHER; PTHR10997:SF8; EXPORTIN-2; 1.
DR   PANTHER; PTHR10997; IMPORTIN-7, 8, 11; 1.
DR   Pfam; PF03378; CAS_CSE1; 1.
DR   Pfam; PF08506; Cse1; 1.
DR   Pfam; PF03810; IBN_N; 1.
DR   SMART; SM00913; IBN_N; 1.
DR   SUPFAM; SSF48371; ARM repeat; 1.
DR   PROSITE; PS50166; IMPORTIN_B_NT; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000008837}.
FT   DOMAIN          28..106
FT                   /note="Importin N-terminal"
FT                   /evidence="ECO:0000259|PROSITE:PS50166"
SQ   SEQUENCE   992 AA;  111394 MW;  2E67AFA57DB9921A CRC64;
     MDPSDTQQLA SLASLFQQTL NPEQRKVAEE QISQLQVQPY FVYLLLTLIQ SESASTAVRL
     AAAIQFKNIC KLRWVVDDEA DEDVPNSVSD EEKYGIRQQL VPVLVSLASA PSPSQAILSQ
     LNESIALVAS YDFPDAWPSL IDELVSQLST DNHHILLSVL STSHAIFKRW RSQFRSDALY
     MEINLVLGKM ANPLLELLQR MHSLLMDPST PSSTMQPLAM CLMLLLQLFY DLSAQDLPPQ
     FEDAIPTLSP MFTSLLSYSR PELIGDEDDV APSPLVKIRS SVCEIFELYA KRYLDVLPQL
     PDYVQAVWDM LGTYGPAEKY DVIVSKAIGF LSTVVRMGNQ RELFQADSTL EQFCTAIILP
     NIQLRDIDEE IFEDNPMEYI RRDLEQSIEI DTRRRAACEF VRALLEQFST QITAICSRHI
     QAYLAEFQAN PMVNWRRKDA AIYLLTSIAA QSSTMQHGVS STNALVDVVQ FFSNHVLQDL
     QPDNDTAKAQ PILQVDAIKY LYTFRNQLTK DQLLSVLPLL VHHLSSTNYV TCTYAAISIE
     RILFIRVNGH RLLNSTDIEP FTRNMLEALF AAVEQHETPE KVAENDHVMK CVMRVLLVAK
     KSVEPYAGQL LEHLVSIIQV TSRNPSNPRF TQFLFESVST LLRFTGSSST AQVAMMEERL
     FPVCTEILQA DVAEYIPYVF QILAQLLEAH ANLDSVRQLP EAYASLLPPL LMPALWEKKS
     HVPALVRLMK AYLKQSPAHL VHKGHVESCL GIYQKLISSR LNDAYGFDLL RSMIIHLPPE
     PLAPYMQPVI TLMLVRLQSS KTDRFSQQFV LFIGFLCGLQ RQGYPEAVVQ LFDSVQSGLF
     GQIAENVISP DLSKLTAKLR FNTAAGIIRL LTQSYSMLST YANAWPALAI SVMHLLLQTG
     PPTHEITEDD GADLDEQGFQ ASYSQLASAG SATDEVGAES WAGPDLWAYF ARQLGEARTL
     RSESLAPLLQ QVPNDVLMKL NEALQREHVT IS
//