ID   A8SAF2_9FIRM            Unreviewed;       296 AA.
AC   A8SAF2;
DT   15-JAN-2008, integrated into UniProtKB/TrEMBL.
DT   15-JAN-2008, sequence version 1.
DT   24-JAN-2024, entry version 64.
DE   SubName: Full=LysR substrate binding domain protein {ECO:0000313|EMBL:EDP22028.1};
GN   ORFNames=FAEPRAM212_01350 {ECO:0000313|EMBL:EDP22028.1};
OS   Faecalibacterium prausnitzii M21/2.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Oscillospiraceae;
OC   Faecalibacterium.
OX   NCBI_TaxID=411485 {ECO:0000313|EMBL:EDP22028.1, ECO:0000313|Proteomes:UP000005945};
RN   [1] {ECO:0000313|EMBL:EDP22028.1, ECO:0000313|Proteomes:UP000005945}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=M21/2 {ECO:0000313|EMBL:EDP22028.1,
RC   ECO:0000313|Proteomes:UP000005945};
RA   Sudarsanam P., Ley R., Guruge J., Turnbaugh P.J., Mahowald M., Liep D.,
RA   Gordon J.;
RT   "Draft genome sequence of Faecalibacterium prausnitzii M21/2.";
RL   Submitted (SEP-2007) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:EDP22028.1, ECO:0000313|Proteomes:UP000005945}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=M21/2 {ECO:0000313|EMBL:EDP22028.1,
RC   ECO:0000313|Proteomes:UP000005945};
RA   Fulton L., Clifton S., Fulton B., Xu J., Minx P., Pepin K.H., Johnson M.,
RA   Thiruvilangam P., Bhonagiri V., Nash W.E., Mardis E.R., Wilson R.K.;
RL   Submitted (SEP-2007) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the LysR transcriptional regulatory family.
CC       {ECO:0000256|ARBA:ARBA00009437}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EDP22028.1}.
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DR   EMBL; ABED02000024; EDP22028.1; -; Genomic_DNA.
DR   RefSeq; WP_005923105.1; NZ_DS483499.1.
DR   AlphaFoldDB; A8SAF2; -.
DR   GeneID; 75068167; -.
DR   HOGENOM; CLU_039613_6_1_9; -.
DR   Proteomes; UP000005945; Unassembled WGS sequence.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR   CDD; cd05466; PBP2_LTTR_substrate; 1.
DR   Gene3D; 3.40.190.290; -; 1.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR   InterPro; IPR005119; LysR_subst-bd.
DR   InterPro; IPR000847; Tscrpt_reg_HTH_LysR.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   PANTHER; PTHR30126; HTH-TYPE TRANSCRIPTIONAL REGULATOR; 1.
DR   PANTHER; PTHR30126:SF40; HTH-TYPE TRANSCRIPTIONAL REGULATOR GLTR; 1.
DR   Pfam; PF00126; HTH_1; 1.
DR   Pfam; PF03466; LysR_substrate; 1.
DR   PRINTS; PR00039; HTHLYSR.
DR   SUPFAM; SSF53850; Periplasmic binding protein-like II; 1.
DR   SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR   PROSITE; PS50931; HTH_LYSR; 1.
PE   3: Inferred from homology;
KW   Transcription {ECO:0000256|ARBA:ARBA00023163};
KW   Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT   DOMAIN          1..58
FT                   /note="HTH lysR-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50931"
SQ   SEQUENCE   296 AA;  32994 MW;  8B5835A11EAD6D36 CRC64;
     MELRTVNTFL HIAELHSFSR TARQLGYSQS AVSSQIAQLE AELGTPLFDR VGKTVRLTDA
     GQTFLGYART LLETAQQAQA ALQPAQQVRG SLRIALADSV CSTFLPELLQ RYHARCPQVE
     LVLHTASTDE MLQLLSTNQV DLVYTLDQPL LQPALVLAAD VPEPVCFIAS PQHPLAQESV
     LPLDILPRQE FLLTERGMSY RDALDQCMAA HGLAIHPYLE LGSAALLCQM VEQGMGLSFL
     PEYIVRSALA EGRLARLNVP DCTVMMHRQL FYHRDKWVTP QMNVFIELVR QGTQTK
//