ID   A8TLE8_9PROT            Unreviewed;       388 AA.
AC   A8TLE8;
DT   15-JAN-2008, integrated into UniProtKB/TrEMBL.
DT   15-JAN-2008, sequence version 1.
DT   24-JAN-2024, entry version 39.
DE   SubName: Full=Methionine synthase, vitamin-B12 independent {ECO:0000313|EMBL:EDP66046.1};
GN   ORFNames=BAL199_23904 {ECO:0000313|EMBL:EDP66046.1};
OS   alpha proteobacterium BAL199.
OC   Bacteria; Pseudomonadota; Alphaproteobacteria.
OX   NCBI_TaxID=331869 {ECO:0000313|EMBL:EDP66046.1, ECO:0000313|Proteomes:UP000003417};
RN   [1] {ECO:0000313|EMBL:EDP66046.1, ECO:0000313|Proteomes:UP000003417}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=BAL199 {ECO:0000313|EMBL:EDP66046.1,
RC   ECO:0000313|Proteomes:UP000003417};
RA   Hagstrom A., Ferriera S., Johnson J., Kravitz S., Beeson K., Sutton G.,
RA   Rogers Y.-H., Friedman R., Frazier M., Venter J.C.;
RL   Submitted (OCT-2007) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EDP66046.1}.
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DR   EMBL; ABHC01000002; EDP66046.1; -; Genomic_DNA.
DR   AlphaFoldDB; A8TLE8; -.
DR   STRING; 331869.BAL199_23904; -.
DR   eggNOG; COG0620; Bacteria.
DR   OrthoDB; 244285at2; -.
DR   Proteomes; UP000003417; Unassembled WGS sequence.
DR   GO; GO:0003871; F:5-methyltetrahydropteroyltriglutamate-homocysteine S-methyltransferase activity; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0009086; P:methionine biosynthetic process; IEA:InterPro.
DR   CDD; cd03311; CIMS_C_terminal_like; 1.
DR   Gene3D; 3.20.20.210; -; 1.
DR   InterPro; IPR002629; Met_Synth_C/arc.
DR   InterPro; IPR038071; UROD/MetE-like_sf.
DR   PANTHER; PTHR43844; METHIONINE SYNTHASE; 1.
DR   PANTHER; PTHR43844:SF2; SYNTHASE, VITAMIN-B12 INDEPENDENT, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G12060)-RELATED; 1.
DR   Pfam; PF01717; Meth_synt_2; 1.
DR   SUPFAM; SSF51726; UROD/MetE-like; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000003417}.
FT   DOMAIN          119..358
FT                   /note="Cobalamin-independent methionine synthase MetE C-
FT                   terminal/archaeal"
FT                   /evidence="ECO:0000259|Pfam:PF01717"
SQ   SEQUENCE   388 AA;  42751 MW;  38AE71E67A6B54E0 CRC64;
     MVTAPTRRIL TTHAGSLPRP QRLVQLYAHR VNGEPVDEAR ITAEGEAATR DVVARQRDAG
     IDIPSDGEQV REAFFLYVQR RMSGFGGQWA RTGSREFDNY PEFAEARRQT LATKTAVSNF
     TPPMAIGPIV YEDRAANEAE ITGFKSALAE VGGGFADAFM TAPSPGIVAT AMKNQYYPDD
     QAYLDAVAEA LKVEYEAAIR HGLILQIDAP DLALERHLTY ADRPVSDFVA FVERVVTTIN
     KAIAGLPRDR VRLHVCWGNY EAPHDQDVAL RDILPAIREA DVSAIMMPFA NARHQHEIKV
     FRDIPLAKHQ SLIVGCIDTT SSFVEHPEVV ADRLERAAEM IGDPTRIMAS TDCGFDTSAG
     MGRLTSDVVW AKLRSLREGA DLASSRLF
//