ID A8U1F8_9PROT Unreviewed; 563 AA.
AC A8U1F8;
DT 15-JAN-2008, integrated into UniProtKB/TrEMBL.
DT 15-JAN-2008, sequence version 1.
DT 24-JAN-2024, entry version 57.
DE SubName: Full=Glucose-methanol-choline oxidoreductase {ECO:0000313|EMBL:EDP61886.1};
GN ORFNames=BAL199_28810 {ECO:0000313|EMBL:EDP61886.1};
OS alpha proteobacterium BAL199.
OC Bacteria; Pseudomonadota; Alphaproteobacteria.
OX NCBI_TaxID=331869 {ECO:0000313|EMBL:EDP61886.1, ECO:0000313|Proteomes:UP000003417};
RN [1] {ECO:0000313|EMBL:EDP61886.1, ECO:0000313|Proteomes:UP000003417}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BAL199 {ECO:0000313|EMBL:EDP61886.1,
RC ECO:0000313|Proteomes:UP000003417};
RA Hagstrom A., Ferriera S., Johnson J., Kravitz S., Beeson K., Sutton G.,
RA Rogers Y.-H., Friedman R., Frazier M., Venter J.C.;
RL Submitted (OCT-2007) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=FAD; Xref=ChEBI:CHEBI:57692;
CC Evidence={ECO:0000256|ARBA:ARBA00001974,
CC ECO:0000256|PIRSR:PIRSR000137-2};
CC -!- SIMILARITY: Belongs to the GMC oxidoreductase family.
CC {ECO:0000256|ARBA:ARBA00010790, ECO:0000256|RuleBase:RU003968}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EDP61886.1}.
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DR EMBL; ABHC01000026; EDP61886.1; -; Genomic_DNA.
DR AlphaFoldDB; A8U1F8; -.
DR STRING; 331869.BAL199_28810; -.
DR eggNOG; COG2303; Bacteria.
DR OrthoDB; 9785276at2; -.
DR Proteomes; UP000003417; Unassembled WGS sequence.
DR GO; GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.
DR GO; GO:0016614; F:oxidoreductase activity, acting on CH-OH group of donors; IEA:InterPro.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 1.
DR Gene3D; 3.30.560.10; Glucose Oxidase, domain 3; 1.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR InterPro; IPR012132; GMC_OxRdtase.
DR InterPro; IPR000172; GMC_OxRdtase_N.
DR InterPro; IPR007867; GMC_OxRtase_C.
DR PANTHER; PTHR11552:SF147; CHOLINE DEHYDROGENASE, MITOCHONDRIAL; 1.
DR PANTHER; PTHR11552; GLUCOSE-METHANOL-CHOLINE GMC OXIDOREDUCTASE; 1.
DR Pfam; PF05199; GMC_oxred_C; 1.
DR Pfam; PF00732; GMC_oxred_N; 1.
DR PIRSF; PIRSF000137; Alcohol_oxidase; 1.
DR SUPFAM; SSF54373; FAD-linked reductases, C-terminal domain; 1.
DR SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
DR PROSITE; PS00623; GMC_OXRED_1; 1.
DR PROSITE; PS00624; GMC_OXRED_2; 1.
PE 3: Inferred from homology;
KW FAD {ECO:0000256|ARBA:ARBA00022827, ECO:0000256|PIRSR:PIRSR000137-2};
KW Flavoprotein {ECO:0000256|ARBA:ARBA00022630,
KW ECO:0000256|RuleBase:RU003968};
KW Reference proteome {ECO:0000313|Proteomes:UP000003417}.
FT DOMAIN 83..106
FT /note="Glucose-methanol-choline oxidoreductase N-terminal"
FT /evidence="ECO:0000259|PROSITE:PS00623"
FT DOMAIN 255..269
FT /note="Glucose-methanol-choline oxidoreductase N-terminal"
FT /evidence="ECO:0000259|PROSITE:PS00624"
FT BINDING 85
FT /ligand="FAD"
FT /ligand_id="ChEBI:CHEBI:57692"
FT /evidence="ECO:0000256|PIRSR:PIRSR000137-2"
SQ SEQUENCE 563 AA; 60614 MW; 5676444320E588E8 CRC64;
MSTLEFDYII VGAGSAGCVL ANRLSADPGL RVLLLEAGGW DRHVWLRLPI GYFRSIFDER
FARQFRTEPG PGTAGRAIVW PRGRVVGGSS TINGLIFIRG QHEDFDDWQR LGADGWDYRS
VLPHFRAFER DGGAPSQYRG SYGELRVSDL RNDDPSCGAW LQAAQQSGLA ANPDFNGETT
HGVGAYQLSI GSRWRESTAR AFLHPVLGRP NLTVTTRAHA TRVLFEGRRA TGVEWAAGGR
RQSGRAVREV ILAGGALQSP QLLQLSGIGP AELLRRHGID VLVDAPGVGG NLQDHYQART
IVRLKRRRSL NDAVRNPLKL ARMGWQWLVD GSGPLTVGAG QVGGAACTEF ARDGRPDIQF
NVMPLSVDKP GDPLHRYSGF TAAAWQCHPA SRGRLAIRSA DPFDAPIIEP NYLAEEIDRR
TLVAGVKMLR EIYRQPAFAD LWDTEMLPGP EVHSDADLLQ FVQRHGGTVF HCCGTCRMGQ
DDGAVVDPQL RVSGVDGLRV IDASVMPTIT SANTNAASIL IGEKGAALVL GQAPAAATLP
ASSGRIAPGD AVPPTALQGG APC
//
