ID A8UY37_9AQUI Unreviewed; 869 AA.
AC A8UY37;
DT 15-JAN-2008, integrated into UniProtKB/TrEMBL.
DT 15-JAN-2008, sequence version 1.
DT 27-MAR-2024, entry version 52.
DE SubName: Full=Predicted signal transduction protein {ECO:0000313|EMBL:EDP74582.1};
GN ORFNames=HG1285_12757 {ECO:0000313|EMBL:EDP74582.1};
OS Hydrogenivirga sp. 128-5-R1-1.
OC Bacteria; Aquificota; Aquificae; Aquificales; Aquificaceae; Hydrogenivirga.
OX NCBI_TaxID=392423 {ECO:0000313|EMBL:EDP74582.1, ECO:0000313|Proteomes:UP000005981};
RN [1] {ECO:0000313|EMBL:EDP74582.1, ECO:0000313|Proteomes:UP000005981}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=128-5-R1-1 {ECO:0000313|EMBL:EDP74582.1,
RC ECO:0000313|Proteomes:UP000005981};
RA Reysenbach A.-L., Ferriera S., Johnson J., Kravitz S., Beeson K.,
RA Sutton G., Rogers Y.-H., Friedman R., Frazier M., Venter J.C.;
RL Submitted (OCT-2007) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EDP74582.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; ABHJ01000013; EDP74582.1; -; Genomic_DNA.
DR RefSeq; WP_008287927.1; NZ_ABHJ01000013.1.
DR AlphaFoldDB; A8UY37; -.
DR OrthoDB; 7057390at2; -.
DR Proteomes; UP000005981; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR CDD; cd01948; EAL; 1.
DR CDD; cd01949; GGDEF; 1.
DR Gene3D; 3.30.70.270; -; 1.
DR Gene3D; 6.10.340.10; -; 1.
DR Gene3D; 3.20.20.450; EAL domain; 1.
DR InterPro; IPR001633; EAL_dom.
DR InterPro; IPR035919; EAL_sf.
DR InterPro; IPR000160; GGDEF_dom.
DR InterPro; IPR003660; HAMP_dom.
DR InterPro; IPR029787; Nucleotide_cyclase.
DR InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR NCBIfam; TIGR00254; GGDEF; 1.
DR PANTHER; PTHR33121; CYCLIC DI-GMP PHOSPHODIESTERASE PDEF; 1.
DR PANTHER; PTHR33121:SF78; CYCLIC DI-GMP PHOSPHODIESTERASE PDEI-RELATED; 1.
DR Pfam; PF00563; EAL; 1.
DR Pfam; PF00990; GGDEF; 1.
DR SMART; SM00052; EAL; 1.
DR SMART; SM00267; GGDEF; 1.
DR SMART; SM00304; HAMP; 1.
DR SUPFAM; SSF141868; EAL domain-like; 1.
DR SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR PROSITE; PS50883; EAL; 1.
DR PROSITE; PS50887; GGDEF; 1.
DR PROSITE; PS50885; HAMP; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000005981};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 28..50
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 231..252
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 254..308
FT /note="HAMP"
FT /evidence="ECO:0000259|PROSITE:PS50885"
FT DOMAIN 484..618
FT /note="GGDEF"
FT /evidence="ECO:0000259|PROSITE:PS50887"
FT DOMAIN 628..869
FT /note="EAL"
FT /evidence="ECO:0000259|PROSITE:PS50883"
SQ SEQUENCE 869 AA; 100025 MW; 08BDE8267F7837CE CRC64;
MTPVMELFSR VNRFIEDRLK VHTYPLKVVL LFAFLIFMSM FLALVVDIAH SVQEVRNEIR
LAAERAAKFR TTAIRDVILG IFQADTALAE LVEKEGTHTL EPFMGTFIIC AKGENFQVGR
LEEGMLREAL QNSQGKKFYF HLFPESWLGI AVLDLKGRTY LFCHRVPYIE DILSKKLGAI
AKYGAEFHFG ERPKFSEGDI LVVHENSYSN ASMFVVVPLK SILGTLIAER VVLYMRLYFV
FILFLSVSYL FWARLMSYPI ERLRKIVEEL DAGNYSVDFS GVAEAKDEFG GIARLLQRFA
RDTQRRFEKL ELILDTALHG VSSPEDVPSF VRETLNRVNE IFGARSSMFV VEDRETGKLL
YVVGSESLEE DGLKELLQFY RERSREVSSV IREPACIREK GSGGCVNLSV FRIEGSVYGG
VLLQMDCNLD SVDEGYLKVV CQHLINTIRL THMATTDPLT GVSNRRVLEH DIAKFGRLVK
RYNKSMSLIM VDIDNFKGIN DTYGHQVGDV VLKKVAKLIE ESVRETDTVY RYGGEEFAVL
CPETDKLGAY ELAERIREKI RETKFWIDTS RVIYITVSLG VASVPEDTDN PDEILAIADI
SLYRAKSEGK DRTAILTDSS DKRLFVERFK REKELRTYIR SGKTLHHLQP IYDLRRGQVF
GYELLFRVVD GDRLYTMGDF ITHVEDLGII EDIDRLTVSR LLKLLSYEEL SNYCFFINVS
PRSLDRGRIL SELNLIPRHQ RPRVYVEITE RETFMDTEEA LRHIEELKNM NFRIVLDDFG
SGFSSISQLR YFVKYLDLIK IDGSFVKRIH RDPYNRAIVE SVKIMADRFS IDLVAEFIER
EEELNVVKVI GIRFGQGFFF GKEEIRSIA
//
