ID A8WP84_CAEBR Unreviewed; 401 AA.
AC A8WP84;
DT 15-JAN-2008, integrated into UniProtKB/TrEMBL.
DT 15-JAN-2008, sequence version 1.
DT 27-MAR-2024, entry version 92.
DE SubName: Full=Protein CBR-TAG-124 {ECO:0000313|EMBL:CAP22290.1};
GN Name=Cbr-tag-124 {ECO:0000313|EMBL:CAP22290.1};
GN ORFNames=CBG00960 {ECO:0000313|WormBase:CBG00960}, CBG_00960
GN {ECO:0000313|EMBL:CAP22290.1};
OS Caenorhabditis briggsae.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC Caenorhabditis.
OX NCBI_TaxID=6238 {ECO:0000313|EMBL:CAP22290.1, ECO:0000313|Proteomes:UP000008549};
RN [1] {ECO:0000313|EMBL:CAP22290.1, ECO:0000313|Proteomes:UP000008549}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AF16 {ECO:0000313|EMBL:CAP22290.1,
RC ECO:0000313|Proteomes:UP000008549};
RX PubMed=14624247; DOI=10.1371/journal.pbio.0000045;
RA Stein L.D., Bao Z., Blasiar D., Blumenthal T., Brent M.R., Chen N.,
RA Chinwalla A., Clarke L., Clee C., Coghlan A., Coulson A., D'Eustachio P.,
RA Fitch D.H., Fulton L.A., Fulton R.E., Griffiths-Jones S., Harris T.W.,
RA Hillier L.W., Kamath R., Kuwabara P.E., Mardis E.R., Marra M.A.,
RA Miner T.L., Minx P., Mullikin J.C., Plumb R.W., Rogers J., Schein J.E.,
RA Sohrmann M., Spieth J., Stajich J.E., Wei C., Willey D., Wilson R.K.,
RA Durbin R., Waterston R.H.;
RT "The genome sequence of Caenorhabditis briggsae: a platform for comparative
RT genomics.";
RL PLoS Biol. 1:166-192(2003).
CC -!- SIMILARITY: Belongs to the tRNA pseudouridine synthase TruA family.
CC {ECO:0000256|ARBA:ARBA00009375}.
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DR EMBL; HE600951; CAP22290.1; -; Genomic_DNA.
DR RefSeq; XP_002629729.1; XM_002629683.1.
DR AlphaFoldDB; A8WP84; -.
DR STRING; 6238.A8WP84; -.
DR EnsemblMetazoa; CBG00960.1; CBG00960.1; WBGene00024264.
DR GeneID; 8573198; -.
DR KEGG; cbr:CBG_00960; -.
DR CTD; 8573198; -.
DR WormBase; CBG00960; CBP13970; WBGene00024264; -.
DR eggNOG; KOG2554; Eukaryota.
DR HOGENOM; CLU_014673_2_0_1; -.
DR InParanoid; A8WP84; -.
DR OMA; YFGWEYN; -.
DR OrthoDB; 167554at2759; -.
DR Proteomes; UP000008549; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0009982; F:pseudouridine synthase activity; IBA:GO_Central.
DR GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR GO; GO:1990481; P:mRNA pseudouridine synthesis; IBA:GO_Central.
DR GO; GO:0031119; P:tRNA pseudouridine synthesis; IBA:GO_Central.
DR CDD; cd02569; PseudoU_synth_ScPus3; 1.
DR Gene3D; 3.30.70.660; Pseudouridine synthase I, catalytic domain, C-terminal subdomain; 1.
DR Gene3D; 3.30.70.580; Pseudouridine synthase I, catalytic domain, N-terminal subdomain; 1.
DR HAMAP; MF_00171; TruA; 1.
DR InterPro; IPR020103; PsdUridine_synth_cat_dom_sf.
DR InterPro; IPR001406; PsdUridine_synth_TruA.
DR InterPro; IPR020097; PsdUridine_synth_TruA_a/b_dom.
DR InterPro; IPR020095; PsdUridine_synth_TruA_C.
DR InterPro; IPR041707; Pus3-like.
DR InterPro; IPR020094; TruA/RsuA/RluB/E/F_N.
DR NCBIfam; TIGR00071; hisT_truA; 1.
DR PANTHER; PTHR11142; PSEUDOURIDYLATE SYNTHASE; 1.
DR PANTHER; PTHR11142:SF5; TRNA PSEUDOURIDINE(38_39) SYNTHASE; 1.
DR Pfam; PF01416; PseudoU_synth_1; 1.
DR SUPFAM; SSF55120; Pseudouridine synthase; 1.
PE 3: Inferred from homology;
KW Isomerase {ECO:0000256|ARBA:ARBA00023235};
KW Reference proteome {ECO:0000313|Proteomes:UP000008549};
KW tRNA processing {ECO:0000256|ARBA:ARBA00022694}.
FT DOMAIN 184..299
FT /note="Pseudouridine synthase I TruA alpha/beta"
FT /evidence="ECO:0000259|Pfam:PF01416"
SQ SEQUENCE 401 AA; 46291 MW; 11346E6465443CF4 CRC64;
MGTKRAGYEI KNNKEAKKPR IFDFSAHPRR KIAIQFFYLG WEHDGLVQQP NTQNTVEHHL
MEALIKTHII EDSIKCDFSR CGRTDKGVSA FKQTAAFLAR STCPDHPNVF WSDSTAEDVK
NSYKSKDEEL PYIKMLNGVL PKTIRVFAWA PVAPTFNARF DCNRRTYKYS FPKAGLDLEK
MREAAKLLIG EHDYSNFCQI DMNKMRLEQS YTRKIYDVTV EQVSTHSEND IYSMVELTVS
GSGFLWHMIR YIVTVLQEVA RGNEQPSLVS DLLDLSKYPS RPHYTLSSDT PLCLFDCGYK
QEDVQWHIHD ATLKTTVSGL QKSWATYQTR CRMMENMIGE LAGMTELSSE DVRKGLHEFV
QDRPISQNYV KFEKRNKCES LDAKKAKIQM KKEAKIEENG V
//
