ID A8WY36_CAEBR Unreviewed; 315 AA.
AC A8WY36;
DT 15-JAN-2008, integrated into UniProtKB/TrEMBL.
DT 16-DEC-2008, sequence version 2.
DT 27-MAR-2024, entry version 92.
DE SubName: Full=Protein CBR-UNC-39 {ECO:0000313|EMBL:CAP25296.2};
GN Name=unc-39 {ECO:0000313|WormBase:CBG04628};
GN Synonyms=Cbr-unc-39 {ECO:0000313|EMBL:CAP25296.2};
GN ORFNames=CBG04628 {ECO:0000313|WormBase:CBG04628}, CBG_04628
GN {ECO:0000313|EMBL:CAP25296.2};
OS Caenorhabditis briggsae.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC Caenorhabditis.
OX NCBI_TaxID=6238 {ECO:0000313|EMBL:CAP25296.2, ECO:0000313|Proteomes:UP000008549};
RN [1] {ECO:0000313|EMBL:CAP25296.2, ECO:0000313|Proteomes:UP000008549}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AF16 {ECO:0000313|EMBL:CAP25296.2,
RC ECO:0000313|Proteomes:UP000008549};
RX PubMed=14624247; DOI=10.1371/journal.pbio.0000045;
RA Stein L.D., Bao Z., Blasiar D., Blumenthal T., Brent M.R., Chen N.,
RA Chinwalla A., Clarke L., Clee C., Coghlan A., Coulson A., D'Eustachio P.,
RA Fitch D.H., Fulton L.A., Fulton R.E., Griffiths-Jones S., Harris T.W.,
RA Hillier L.W., Kamath R., Kuwabara P.E., Mardis E.R., Marra M.A.,
RA Miner T.L., Minx P., Mullikin J.C., Plumb R.W., Rogers J., Schein J.E.,
RA Sohrmann M., Spieth J., Stajich J.E., Wei C., Willey D., Wilson R.K.,
RA Durbin R., Waterston R.H.;
RT "The genome sequence of Caenorhabditis briggsae: a platform for comparative
RT genomics.";
RL PLoS Biol. 1:166-192(2003).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|PROSITE-ProRule:PRU00108,
CC ECO:0000256|RuleBase:RU000682}.
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DR EMBL; HE601135; CAP25296.2; -; Genomic_DNA.
DR AlphaFoldDB; A8WY36; -.
DR STRING; 6238.A8WY36; -.
DR EnsemblMetazoa; CBG04628.1; CBG04628.1; WBGene00027265.
DR WormBase; CBG04628; CBP29289; WBGene00027265; Cbr-unc-39.
DR eggNOG; KOG0775; Eukaryota.
DR HOGENOM; CLU_872206_0_0_1; -.
DR InParanoid; A8WY36; -.
DR OMA; IWHHARY; -.
DR OrthoDB; 602349at2759; -.
DR Proteomes; UP000008549; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0005667; C:transcription regulator complex; IBA:GO_Central.
DR GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; IBA:GO_Central.
DR GO; GO:0000978; F:RNA polymerase II cis-regulatory region sequence-specific DNA binding; IBA:GO_Central.
DR GO; GO:0007411; P:axon guidance; IEA:EnsemblMetazoa.
DR GO; GO:0018991; P:egg-laying behavior; IEA:EnsemblMetazoa.
DR GO; GO:0040011; P:locomotion; IEA:EnsemblMetazoa.
DR GO; GO:0008078; P:mesodermal cell migration; IEA:EnsemblMetazoa.
DR GO; GO:0001764; P:neuron migration; IEA:EnsemblMetazoa.
DR GO; GO:0040017; P:positive regulation of locomotion; IEA:EnsemblMetazoa.
DR GO; GO:0030334; P:regulation of cell migration; IEA:EnsemblMetazoa.
DR GO; GO:0110037; P:regulation of nematode male tail tip morphogenesis; IEA:EnsemblMetazoa.
DR GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IBA:GO_Central.
DR CDD; cd00086; homeodomain; 1.
DR Gene3D; 1.10.10.60; Homeodomain-like; 1.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR017970; Homeobox_CS.
DR InterPro; IPR001356; Homeobox_dom.
DR InterPro; IPR031701; SIX1_SD.
DR PANTHER; PTHR10390:SF44; HOMEOBOX DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR10390; HOMEOBOX PROTEIN SIX; 1.
DR Pfam; PF00046; Homeodomain; 1.
DR Pfam; PF16878; SIX1_SD; 1.
DR SMART; SM00389; HOX; 1.
DR SUPFAM; SSF46689; Homeodomain-like; 1.
DR PROSITE; PS00027; HOMEOBOX_1; 1.
DR PROSITE; PS50071; HOMEOBOX_2; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PROSITE-
KW ProRule:PRU00108};
KW Homeobox {ECO:0000256|ARBA:ARBA00023155, ECO:0000256|PROSITE-
KW ProRule:PRU00108};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|PROSITE-
KW ProRule:PRU00108}; Reference proteome {ECO:0000313|Proteomes:UP000008549}.
FT DOMAIN 211..272
FT /note="Homeobox"
FT /evidence="ECO:0000259|PROSITE:PS50071"
FT DNA_BIND 213..273
FT /note="Homeobox"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00108"
FT REGION 264..290
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 273..289
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 315 AA; 35971 MW; C39C93BDE5464D5B CRC64;
MPDPHLIDTS SYFDCYQQQQ PHQYPILPAS ASSTTSTPST SSILLSSSHF TSGASVPPYS
PTSSHILTPP SVIPTPSPST TSIATFGFPM AEYNLDQMEA ICTSLFQARD GERLVAFFNQ
MKEMYGSNAL DHFGSESIVV AYTYALYHSN DFERLFHLLS TRHFHATFFA DLQEIWHYAR
YKESQLKRGK ELNPVEKYRL RRKFPPPKTI WDGEETVYSF KDSSRKYLKK FFNDVNQYPN
QEQKREISRA TGLKVVQISN WFKNRRQRDK TDNGSPPSSS ASSNGGNEFP PLVDAQRFNL
TAVPFNMNVN MFFDN
//
