ID A8X9T7_CAEBR Unreviewed; 645 AA.
AC A8X9T7;
DT 15-JAN-2008, integrated into UniProtKB/TrEMBL.
DT 15-JAN-2008, sequence version 1.
DT 27-MAR-2024, entry version 85.
DE SubName: Full=Protein CBR-GEI-1 {ECO:0000313|EMBL:CAP29402.1};
GN Name=gei-1 {ECO:0000313|WormBase:CBG09855a};
GN Synonyms=Cbr-gei-1 {ECO:0000313|EMBL:CAP29402.1};
GN ORFNames=CBG09855 {ECO:0000313|WormBase:CBG09855a}, CBG_09855
GN {ECO:0000313|EMBL:CAP29402.1};
OS Caenorhabditis briggsae.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC Caenorhabditis.
OX NCBI_TaxID=6238 {ECO:0000313|EMBL:CAP29402.1, ECO:0000313|Proteomes:UP000008549};
RN [1] {ECO:0000313|EMBL:CAP29402.1, ECO:0000313|Proteomes:UP000008549}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AF16 {ECO:0000313|EMBL:CAP29402.1,
RC ECO:0000313|Proteomes:UP000008549};
RX PubMed=14624247; DOI=10.1371/journal.pbio.0000045;
RA Stein L.D., Bao Z., Blasiar D., Blumenthal T., Brent M.R., Chen N.,
RA Chinwalla A., Clarke L., Clee C., Coghlan A., Coulson A., D'Eustachio P.,
RA Fitch D.H., Fulton L.A., Fulton R.E., Griffiths-Jones S., Harris T.W.,
RA Hillier L.W., Kamath R., Kuwabara P.E., Mardis E.R., Marra M.A.,
RA Miner T.L., Minx P., Mullikin J.C., Plumb R.W., Rogers J., Schein J.E.,
RA Sohrmann M., Spieth J., Stajich J.E., Wei C., Willey D., Wilson R.K.,
RA Durbin R., Waterston R.H.;
RT "The genome sequence of Caenorhabditis briggsae: a platform for comparative
RT genomics.";
RL PLoS Biol. 1:166-192(2003).
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DR EMBL; HE601459; CAP29402.1; -; Genomic_DNA.
DR RefSeq; XP_002641556.1; XM_002641510.1.
DR AlphaFoldDB; A8X9T7; -.
DR STRING; 6238.A8X9T7; -.
DR GeneID; 8583547; -.
DR KEGG; cbr:CBG_09855; -.
DR CTD; 8583547; -.
DR WormBase; CBG09855a; CBP40892; WBGene00031371; Cbr-gei-1.
DR eggNOG; KOG2200; Eukaryota.
DR HOGENOM; CLU_424678_0_0_1; -.
DR InParanoid; A8X9T7; -.
DR OMA; NIFIHEH; -.
DR OrthoDB; 2883046at2759; -.
DR Proteomes; UP000008549; Unassembled WGS sequence.
DR GO; GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
DR GO; GO:0008289; F:lipid binding; IEA:InterPro.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR Gene3D; 3.30.530.20; -; 1.
DR Gene3D; 1.10.555.10; Rho GTPase activation protein; 1.
DR InterPro; IPR008936; Rho_GTPase_activation_prot.
DR InterPro; IPR000198; RhoGAP_dom.
DR InterPro; IPR023393; START-like_dom_sf.
DR InterPro; IPR002913; START_lipid-bd_dom.
DR PANTHER; PTHR12659:SF7; CROSSVEINLESS C, ISOFORM C; 1.
DR PANTHER; PTHR12659; RHO-TYPE GTPASE ACTIVATING PROTEIN; 1.
DR Pfam; PF00620; RhoGAP; 1.
DR Pfam; PF01852; START; 1.
DR SMART; SM00324; RhoGAP; 1.
DR SUPFAM; SSF55961; Bet v1-like; 1.
DR SUPFAM; SSF48350; GTPase activation domain, GAP; 1.
DR PROSITE; PS50238; RHOGAP; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000008549}.
FT DOMAIN 266..481
FT /note="Rho-GAP"
FT /evidence="ECO:0000259|PROSITE:PS50238"
FT REGION 43..68
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 109..143
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 645 AA; 72471 MW; 61719569B4F21087 CRC64;
MPFVSYLYPG HHNMLDRFDK TFELPSRSLI PDRMYDDLDV LPKSSKTTNL NSNSTSNSNS
LDNNKNSENI SMYNDGYYTH EIKPALPRHH NISKPENLKV NTEKIEVLSS SDEPIGRTTL
TKRSDSGLGS SLSRSPSGPH TQRIRQSLLP YSNATSAGIS SAYSCCSWES SAKLSDEQPF
FAEIELARSI DSLNLIEMTR LRKTAYLRLC STLERNIEGK VNLTDPDQDE LPSKHVWSVH
RLIKRMKIND GQKNQKDNED GAVFGVGLDV IFQKTGYFLP RPILEVMKFL RNIAPETVGI
FRKNGVKSRI AELRSIIESY SGNTDVFVGE NILDSTQVHD VADLLKQYLR DLPEPLMTIK
MSEVFANICS VVPDVDRMTS LQYAILLLPD ENREALKTLL LFLKEVSRNS QVNNMTAQNL
SVCFTPSLFQ LGASRLDKVT PGSRRHKTVG ATGLPSEKEM KEARACQLCL TMLIEYVQTI
FMVPDGLDEH TDAEDDNPNL TDLGLKGPRS FLVDRVIDMI REHSDGWKNW TIEGSFRGVE
VSSRRPFHSS GLTEIRGACA IAERSVKCSE DQLLGGIAAT IFDQRFLIEP VSGGQSRVNY
IARVDLKGRS LQWYNKSFGS IMCRHLDRLR ESFLLGDKGG PETNV
//
