ID A8XII4_CAEBR Unreviewed; 827 AA.
AC A8XII4;
DT 15-JAN-2008, integrated into UniProtKB/TrEMBL.
DT 15-JAN-2008, sequence version 1.
DT 27-MAR-2024, entry version 98.
DE SubName: Full=Protein CBG13704 {ECO:0000313|EMBL:CAP32458.1};
GN ORFNames=CBG13704 {ECO:0000313|EMBL:CAP32458.1,
GN ECO:0000313|WormBase:CBG13704}, CBG_13704
GN {ECO:0000313|EMBL:CAP32458.1};
OS Caenorhabditis briggsae.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC Caenorhabditis.
OX NCBI_TaxID=6238 {ECO:0000313|EMBL:CAP32458.1, ECO:0000313|Proteomes:UP000008549};
RN [1] {ECO:0000313|EMBL:CAP32458.1, ECO:0000313|Proteomes:UP000008549}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AF16 {ECO:0000313|EMBL:CAP32458.1,
RC ECO:0000313|Proteomes:UP000008549};
RX PubMed=14624247; DOI=10.1371/journal.pbio.0000045;
RA Stein L.D., Bao Z., Blasiar D., Blumenthal T., Brent M.R., Chen N.,
RA Chinwalla A., Clarke L., Clee C., Coghlan A., Coulson A., D'Eustachio P.,
RA Fitch D.H., Fulton L.A., Fulton R.E., Griffiths-Jones S., Harris T.W.,
RA Hillier L.W., Kamath R., Kuwabara P.E., Mardis E.R., Marra M.A.,
RA Miner T.L., Minx P., Mullikin J.C., Plumb R.W., Rogers J., Schein J.E.,
RA Sohrmann M., Spieth J., Stajich J.E., Wei C., Willey D., Wilson R.K.,
RA Durbin R., Waterston R.H.;
RT "The genome sequence of Caenorhabditis briggsae: a platform for comparative
RT genomics.";
RL PLoS Biol. 1:166-192(2003).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR EMBL; HE600943; CAP32458.1; -; Genomic_DNA.
DR RefSeq; XP_002632472.1; XM_002632426.1.
DR AlphaFoldDB; A8XII4; -.
DR STRING; 6238.A8XII4; -.
DR GeneID; 8574469; -.
DR KEGG; cbr:CBG_13704; -.
DR CTD; 8574469; -.
DR WormBase; CBG13704; CBP43856; WBGene00034428; -.
DR eggNOG; KOG0527; Eukaryota.
DR HOGENOM; CLU_342645_0_0_1; -.
DR InParanoid; A8XII4; -.
DR OrthoDB; 2878816at2759; -.
DR Proteomes; UP000008549; Unassembled WGS sequence.
DR GO; GO:0035267; C:NuA4 histone acetyltransferase complex; IBA:GO_Central.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0006325; P:chromatin organization; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR Gene3D; 2.30.30.140; -; 1.
DR Gene3D; 1.10.30.10; High mobility group box domain; 1.
DR Gene3D; 1.10.274.30; MRG domain; 1.
DR InterPro; IPR016197; Chromo-like_dom_sf.
DR InterPro; IPR009071; HMG_box_dom.
DR InterPro; IPR036910; HMG_box_dom_sf.
DR InterPro; IPR008676; MRG.
DR InterPro; IPR038217; MRG_C_sf.
DR InterPro; IPR026541; MRG_dom.
DR PANTHER; PTHR10880; MORTALITY FACTOR 4-LIKE PROTEIN; 1.
DR PANTHER; PTHR10880:SF48; MRG DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF00505; HMG_box; 1.
DR Pfam; PF05712; MRG; 1.
DR SMART; SM00398; HMG; 2.
DR SUPFAM; SSF54160; Chromo domain-like; 1.
DR SUPFAM; SSF47095; HMG-box; 2.
DR PROSITE; PS50118; HMG_BOX_2; 1.
DR PROSITE; PS51640; MRG; 1.
PE 4: Predicted;
KW Chromatin regulator {ECO:0000256|ARBA:ARBA00022853};
KW DNA-binding {ECO:0000256|PROSITE-ProRule:PRU00267};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|PROSITE-
KW ProRule:PRU00267}; Reference proteome {ECO:0000313|Proteomes:UP000008549};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 121..189
FT /note="HMG box"
FT /evidence="ECO:0000259|PROSITE:PS50118"
FT DNA_BIND 121..189
FT /note="HMG box"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00267"
FT REGION 1..26
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 460..516
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 584..609
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 9..26
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 481..516
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 591..609
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 827 AA; 94922 MW; 8552298F625EFCB4 CRC64;
MPRADTMLHL RNVSSSPDSS ENYNPYPVSA KKPPVLAFGL WRQDNQHKFD GMYSNISATE
KITKMRTVWR HHTSAEEREF YYAKEKQLKM QRDHSAIQEP IPFNDCSQSK IQQPNKPEQH
VKRPLNPFMV YCQVRRAELA VTDPGLPSAE ILKRLGAGWG AMSVEEKRPF YDEASKLKEE
LYKAHPNYKY APQKKPAVHV STPIKLAMTP IKPAAIPTRS VLTPSVAPNV NQLHKISTSQ
PVIPTTPLNP IPQQNPTRYE QCHQPTPTHD YCFKYPRTSG VVIHEGPSPP YCVRVAFLSP
SSSFFQACAL GETRNGPICV CCSQIVIDRC GGRMSSPIFT TNEIFVCLHE KDGSKFPYSA
KIMAIKEIGS IQFYMIHYRG WKSTTDIRIP VGEEAGRMYK GSLKEYGEKF HVDISPDAWD
AEKKCKRKAV DNLERSFVKK ERIQEENVYK KVYVAKRRKL REDSEEATSS DALRRSRGDP
GATTSEVKDS RISKDKENKA KSLKQRDSEN QIKKTSKVIP IDDAKILEGQ GTSTKIRIGQ
TEENLHKEDE IQNLKPGNPE ELIHEPMNLP DQSKEDILAE IQNLPQAESP KKRGPIEKVP
DSEVAKKVQD KDPKVNIPVL EYAVQKKRNN PGYYIPKNDP VYNERMSVLR ARHAGTLDEV
KLTDGLGKIL VDDYIMVHSE KKIPKVPAEW VVVNILEEYK NSKTNDSDSY GINDLNTMIP
FYMDKHFRSL CYSVEVPNYE QRLIQEVLRQ KLIFEDVKDL DPKIFKASEH YGLVHLLRLL
TEIDKFVMMY NTGHSLERTR TILIDFMKFL DIKKYEFYHK EKDYMDA
//
