ID A8XSR6_CAEBR Unreviewed; 1188 AA.
AC A8XSR6;
DT 15-JAN-2008, integrated into UniProtKB/TrEMBL.
DT 16-DEC-2008, sequence version 2.
DT 27-MAR-2024, entry version 92.
DE SubName: Full=Protein CBG17988 {ECO:0000313|EMBL:CAP35518.2};
GN ORFNames=CBG17988 {ECO:0000313|EMBL:CAP35518.2,
GN ECO:0000313|WormBase:CBG17988}, CBG_17988
GN {ECO:0000313|EMBL:CAP35518.2};
OS Caenorhabditis briggsae.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC Caenorhabditis.
OX NCBI_TaxID=6238 {ECO:0000313|EMBL:CAP35518.2, ECO:0000313|Proteomes:UP000008549};
RN [1] {ECO:0000313|EMBL:CAP35518.2, ECO:0000313|Proteomes:UP000008549}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AF16 {ECO:0000313|EMBL:CAP35518.2,
RC ECO:0000313|Proteomes:UP000008549};
RX PubMed=14624247; DOI=10.1371/journal.pbio.0000045;
RA Stein L.D., Bao Z., Blasiar D., Blumenthal T., Brent M.R., Chen N.,
RA Chinwalla A., Clarke L., Clee C., Coghlan A., Coulson A., D'Eustachio P.,
RA Fitch D.H., Fulton L.A., Fulton R.E., Griffiths-Jones S., Harris T.W.,
RA Hillier L.W., Kamath R., Kuwabara P.E., Mardis E.R., Marra M.A.,
RA Miner T.L., Minx P., Mullikin J.C., Plumb R.W., Rogers J., Schein J.E.,
RA Sohrmann M., Spieth J., Stajich J.E., Wei C., Willey D., Wilson R.K.,
RA Durbin R., Waterston R.H.;
RT "The genome sequence of Caenorhabditis briggsae: a platform for comparative
RT genomics.";
RL PLoS Biol. 1:166-192(2003).
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00076}.
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DR EMBL; HE600963; CAP35518.2; -; Genomic_DNA.
DR AlphaFoldDB; A8XSR6; -.
DR STRING; 6238.A8XSR6; -.
DR WormBase; CBG17988; CBP43510; WBGene00037488; -.
DR eggNOG; KOG4291; Eukaryota.
DR HOGENOM; CLU_272651_0_0_1; -.
DR InParanoid; A8XSR6; -.
DR OMA; QWFNDCS; -.
DR OrthoDB; 5490156at2759; -.
DR Proteomes; UP000008549; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR GO; GO:0007160; P:cell-matrix adhesion; IEA:InterPro.
DR CDD; cd00054; EGF_CA; 5.
DR Gene3D; 2.10.25.10; Laminin; 8.
DR Gene3D; 2.170.300.10; Tie2 ligand-binding domain superfamily; 2.
DR InterPro; IPR001881; EGF-like_Ca-bd_dom.
DR InterPro; IPR000742; EGF-like_dom.
DR InterPro; IPR000152; EGF-type_Asp/Asn_hydroxyl_site.
DR InterPro; IPR018097; EGF_Ca-bd_CS.
DR InterPro; IPR024731; EGF_dom.
DR InterPro; IPR009030; Growth_fac_rcpt_cys_sf.
DR InterPro; IPR003886; NIDO_dom.
DR PANTHER; PTHR24050:SF20; -; 1.
DR PANTHER; PTHR24050; PA14 DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF12947; EGF_3; 2.
DR Pfam; PF07645; EGF_CA; 5.
DR Pfam; PF06119; NIDO; 2.
DR SMART; SM00181; EGF; 8.
DR SMART; SM00179; EGF_CA; 7.
DR SMART; SM00539; NIDO; 2.
DR SUPFAM; SSF57196; EGF/Laminin; 2.
DR SUPFAM; SSF57184; Growth factor receptor domain; 1.
DR PROSITE; PS00010; ASX_HYDROXYL; 5.
DR PROSITE; PS01186; EGF_2; 6.
DR PROSITE; PS50026; EGF_3; 6.
DR PROSITE; PS01187; EGF_CA; 4.
DR PROSITE; PS51220; NIDO; 1.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW EGF-like domain {ECO:0000256|ARBA:ARBA00022536, ECO:0000256|PROSITE-
KW ProRule:PRU00076}; Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000008549};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}; Signal {ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..19
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 20..1188
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5002733645"
FT TRANSMEM 1110..1135
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 115..252
FT /note="NIDO"
FT /evidence="ECO:0000259|PROSITE:PS51220"
FT DOMAIN 478..518
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 519..563
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 564..605
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 606..644
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 911..951
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 952..994
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT REGION 397..422
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1188 AA; 131320 MW; 99EA867BB7D3A5AF CRC64;
MRGDGILVVL LIHLSLVFGL HPFYGHQRYR RQILDEPNQQ IDLNITVPYI FSARLYTYGA
NRGDIPIHGR QEIYKLENPI HFMGNVYDSV YISRDGSVGF TEKRQKPSAL PVEEPTIAVF
WQPATLGNVW YRETSDVNIM NLAHNEVNIQ YRYGSQFRVR SVVLITWEGV KDPIVPESEG
NTFQLALIIG DSMTFAHFIY SKLNYNTNAI AGFSTGQSSY SLPDSATHDA ILLSEKSDIG
IPGEWLFRVD GNQIYLCGAG FKGLECIESC APSQWFNDCS KSCHCDGGDS CDQENGRCPN
GKCSPGWTSE PICDEDLDEC EMGIDNCPNE QPDCLNTPGS FLCLCFEYDE EKQKCKNSKP
APPSAPIPVD VIPMHPTFTR KPAPAKVTVS PRNRFKSTTA RTTQAITTHS STEIPTTTRE
KTMSTPLLTT EVVTRTTTTP TVVTTPSACS RCDQNAKCSN GICACSKGFT GDGFRCYDVD
ECQIPEDVCG DHSICSNTIG NFECTCHGGY RFEEGKCQDV DECRESPKIC GDPNKGTRCI
NKDGSFECLC KDGYEGDPSS ECRDVDECKN GDACGPNSQC TNTEGGYECE CLPGFERIAE
GAHCTDRDEC AVEPCHPAAT CSNTRGSYKC ECIDGFVGDG KTCHETILYP ISNDSTVIPR
SWDSNTAIPL AKEITIFGKK YSKIYLSTNG IISFEEPLQG LIDHADTLKK PAIFALHAQF
DYIRDGLVAY TYINDTDAVT LPLLMRSSIG IQTSMGIENF HTKRLHIFTF DRVRQSGSEN
FNSFQIVLAE SDKDFTILSL IYEKVQARGP MTGISTPSRF LMLPNKRLTS GSNVGQPGKW
MFRVDVADLQ TCPPGRVGEP FCDRECAAGH YGINCVSTCH CDGSVACDVV TGMCPGALCR
AGWEGSSCDQ DIDECGMNLV TCADGSQCVN TRGGYRCDCK KGFVPVGKEC KQIDQCLSRF
SVPCSRNAEC VKSEGVNPKC VCRKGYHGDG FRCTTRENVK SAGGNRLVSD LTHHLMEVDD
LPGANTTDSS VPSSSENPFV MKNWVPDRVG ETTPSPQRPK FVTVQTPPLF YTAPPIKPKM
NDKDMDLMDG EKPRAEESGS FPCKKNLISV LYIIGSAMLF IWIVLIILVC GVMYMNKRRR
RNVERQQYAA MRGWKGGQFH SRSSRMITTS NPNVIYGQTP RITPYESY
//
