ID A8XXM8_CAEBR Unreviewed; 533 AA.
AC A8XXM8;
DT 15-JAN-2008, integrated into UniProtKB/TrEMBL.
DT 16-DEC-2008, sequence version 2.
DT 27-MAR-2024, entry version 62.
DE SubName: Full=Protein CBG20372 {ECO:0000313|EMBL:CAP37397.2};
GN Name=wac-1.1 {ECO:0000313|WormBase:CBG20372a};
GN ORFNames=CBG20372 {ECO:0000313|EMBL:CAP37397.2,
GN ECO:0000313|WormBase:CBG20372a}, CBG_20372
GN {ECO:0000313|EMBL:CAP37397.2};
OS Caenorhabditis briggsae.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC Caenorhabditis.
OX NCBI_TaxID=6238 {ECO:0000313|EMBL:CAP37397.2, ECO:0000313|Proteomes:UP000008549};
RN [1] {ECO:0000313|EMBL:CAP37397.2, ECO:0000313|Proteomes:UP000008549}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AF16 {ECO:0000313|EMBL:CAP37397.2,
RC ECO:0000313|Proteomes:UP000008549};
RX PubMed=14624247; DOI=10.1371/journal.pbio.0000045;
RA Stein L.D., Bao Z., Blasiar D., Blumenthal T., Brent M.R., Chen N.,
RA Chinwalla A., Clarke L., Clee C., Coghlan A., Coulson A., D'Eustachio P.,
RA Fitch D.H., Fulton L.A., Fulton R.E., Griffiths-Jones S., Harris T.W.,
RA Hillier L.W., Kamath R., Kuwabara P.E., Mardis E.R., Marra M.A.,
RA Miner T.L., Minx P., Mullikin J.C., Plumb R.W., Rogers J., Schein J.E.,
RA Sohrmann M., Spieth J., Stajich J.E., Wei C., Willey D., Wilson R.K.,
RA Durbin R., Waterston R.H.;
RT "The genome sequence of Caenorhabditis briggsae: a platform for comparative
RT genomics.";
RL PLoS Biol. 1:166-192(2003).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR EMBL; HE601396; CAP37397.2; -; Genomic_DNA.
DR AlphaFoldDB; A8XXM8; -.
DR STRING; 6238.A8XXM8; -.
DR WormBase; CBG20372a; CBP40324; WBGene00039368; Cbr-wac-1.1.
DR eggNOG; ENOG502QQEE; Eukaryota.
DR HOGENOM; CLU_043586_0_0_1; -.
DR InParanoid; A8XXM8; -.
DR OMA; KMRRHSI; -.
DR OrthoDB; 2884095at2759; -.
DR Proteomes; UP000008549; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0003682; F:chromatin binding; IBA:GO_Central.
DR GO; GO:0000993; F:RNA polymerase II complex binding; IBA:GO_Central.
DR GO; GO:0006325; P:chromatin organization; IEA:UniProtKB-KW.
DR GO; GO:1904263; P:positive regulation of TORC1 signaling; IBA:GO_Central.
DR GO; GO:0010506; P:regulation of autophagy; IBA:GO_Central.
DR CDD; cd00201; WW; 1.
DR Gene3D; 2.20.70.10; -; 1.
DR InterPro; IPR038867; WAC.
DR InterPro; IPR001202; WW_dom.
DR InterPro; IPR036020; WW_dom_sf.
DR PANTHER; PTHR15911; WW DOMAIN-CONTAINING ADAPTER PROTEIN WITH COILED-COIL; 1.
DR PANTHER; PTHR15911:SF6; WW DOMAIN-CONTAINING ADAPTER PROTEIN WITH COILED-COIL; 1.
DR Pfam; PF00397; WW; 1.
DR SMART; SM00456; WW; 1.
DR SUPFAM; SSF101447; Formin homology 2 domain (FH2 domain); 1.
DR SUPFAM; SSF51045; WW domain; 1.
DR PROSITE; PS01159; WW_DOMAIN_1; 1.
DR PROSITE; PS50020; WW_DOMAIN_2; 1.
PE 4: Predicted;
KW Chromatin regulator {ECO:0000256|ARBA:ARBA00022853};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000008549}.
FT DOMAIN 25..54
FT /note="WW"
FT /evidence="ECO:0000259|PROSITE:PS50020"
FT REGION 167..389
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 167..183
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 184..199
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 200..214
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 215..243
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 244..266
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 269..334
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 533 AA; 58723 MW; 5610AF107692264A CRC64;
MAPSPINPSP PPTKLYYVGQ CRTCNGWVEQ MSSSGKLYYY QQKTEVSQWH PPNEWTLSSP
PDLQKWRDTV IREAAKQCPP PPPQPPGGMP LTPHGIPYMP PPLYHPHPHL PYPPPHTMPP
PAHYYPQAPP PPPQAYYHHH GMAPIPQHHS GPTTPVARMA PVSFGSAHVP VPPPPPLAPP
PSRPISMATS STSSTPTTLN CAVPPPPPPL QRTPRTPASM FQSPRDTFSI PPSSSSVSST
PSSSTAAPPP PPPPPPPPPP PPMEGSSRTF ASPAGSIQMS PSARTPSSSS SIGPAASTSS
QSRESLYKKE FSQQQMSSRT SSNKRPQMSP PKELSSSKRR YHDDGSTPSS SSARQSRNER
ISFDGRSPEG MSGPIQHETP RKSSPQSLEN EKYLKYKLPH PEMYKFFDKD MANEKSDALG
LTEGDEKKTL IKMRRHSIWM DNDTISKFQG FEACRNYCEA KKMMQEIVIS RIQHLDIIKS
LFSQCPAGPG RACLFLLFLL SNSVHRQDTV FQIIPFCSTR GALPYLIELV RKH
//
