ID A9A9R8_METM6 Unreviewed; 751 AA.
AC A9A9R8;
DT 15-JAN-2008, integrated into UniProtKB/TrEMBL.
DT 15-JAN-2008, sequence version 1.
DT 27-MAR-2024, entry version 102.
DE SubName: Full=ERCC4 domain protein {ECO:0000313|EMBL:ABX02091.1};
GN OrderedLocusNames=MmarC6_1278 {ECO:0000313|EMBL:ABX02091.1};
OS Methanococcus maripaludis (strain C6 / ATCC BAA-1332).
OC Archaea; Euryarchaeota; Methanomada group; Methanococci; Methanococcales;
OC Methanococcaceae; Methanococcus.
OX NCBI_TaxID=444158 {ECO:0000313|EMBL:ABX02091.1};
RN [1] {ECO:0000313|EMBL:ABX02091.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=C6 {ECO:0000313|EMBL:ABX02091.1};
RG US DOE Joint Genome Institute;
RA Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E.,
RA Tice H., Pitluck S., Clum A., Schmutz J., Larimer F., Land M., Hauser L.,
RA Kyrpides N., Mikhailova N., Sieprawska-Lupa M., Whitman W.B.,
RA Richardson P.;
RT "Complete sequence of Methanococcus maripaludis C6.";
RL Submitted (OCT-2007) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; CP000867; ABX02091.1; -; Genomic_DNA.
DR AlphaFoldDB; A9A9R8; -.
DR STRING; 444158.MmarC6_1278; -.
DR KEGG; mmx:MmarC6_1278; -.
DR eggNOG; arCOG00872; Archaea.
DR HOGENOM; CLU_002513_3_1_2; -.
DR OrthoDB; 9764at2157; -.
DR PhylomeDB; A9A9R8; -.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR GO; GO:0004518; F:nuclease activity; IEA:InterPro.
DR GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
DR CDD; cd12089; Hef_ID; 1.
DR CDD; cd20075; XPF_nuclease_XPF_arch; 1.
DR Gene3D; 3.40.50.10130; -; 1.
DR Gene3D; 1.10.150.20; 5' to 3' exonuclease, C-terminal subdomain; 1.
DR Gene3D; 1.20.1320.20; hef helicase domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR041663; DisA/LigA_HHH.
DR InterPro; IPR006166; ERCC4_domain.
DR InterPro; IPR041755; Hef_ID.
DR InterPro; IPR006935; Helicase/UvrB_N.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR003583; Hlx-hairpin-Hlx_DNA-bd_motif.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR011335; Restrct_endonuc-II-like.
DR InterPro; IPR010994; RuvA_2-like.
DR PANTHER; PTHR14025; FANCONI ANEMIA GROUP M FANCM FAMILY MEMBER; 1.
DR PANTHER; PTHR14025:SF20; FANCONI ANEMIA GROUP M PROTEIN; 1.
DR Pfam; PF02732; ERCC4; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR Pfam; PF12826; HHH_2; 1.
DR Pfam; PF04851; ResIII; 1.
DR Pfam; PF21210; RNA_helicase_helical; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00891; ERCC4; 1.
DR SMART; SM00490; HELICc; 1.
DR SMART; SM00278; HhH1; 2.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF52980; Restriction endonuclease-like; 1.
DR SUPFAM; SSF47781; RuvA domain 2-like; 1.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW DNA damage {ECO:0000256|ARBA:ARBA00022763};
KW DNA repair {ECO:0000256|ARBA:ARBA00023204};
KW Helicase {ECO:0000256|ARBA:ARBA00022806};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741}.
FT DOMAIN 22..186
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 337..504
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
FT REGION 521..542
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 479..509
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 523..541
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 751 AA; 85603 MW; 2742EAD60638C90D CRC64;
MHVNHPLIKP ESIEARIYQQ LVVASALKQN TLCVLGTGLG KTAIAALTIA GILSKQDGKV
LIIAPSRPLV DQHFKSMNQF LNIDSEKIVI LNGKISPKKR EAMWESGKIF IATPQVAEND
IISKMLKPSQ FSLLIADEAH HTTGNHSYTF VANKFKKKSH VLGLTASPGS NIERIIEICG
NLGIEHVEIK TEEDPDVAPY VAKVKMRPKR VELPEEFEIN LTLLKNALKD RLRDLKENRV
IHTINVNKSE LLGLNKKIMT MDDNIKYEML RISSEAVKLE HAIEMLETQG RSTFLNYYQK
LLTQNTKSAK EITNDPRFIQ VVKNLNELDI EHPKYEKMLE ILKEILKENE KIIIFAQYRD
TVQKIVDLLS ENGIEAIMFV GQSNKDGKGM SQTEQAKAIE RFKSDVNVLV STSVSEEGID
ISGVNYVLFY EPVPSEIRMI QRRGRAARGE GGQVIVLIAE KTRDEGYYRA GLAKEKNMKN
ILKNMQTSLN KKLKELTEER EEVEKTENKD HYMDLRSVVG SKTSVKSEEK KPTKLDKKSK
SGAPNKATII LDSRERHIGR YLSEKAEVEF KTLEIGDYIL SDRVAVERKT AEDFENSIID
KRLFNQVMDL KKYERPLMII EGNEFVRIHE NAIRGMMFSI MIDYQIPIMF SRDIEDTADI
LVKLAEREQI KEKREISIRY GKRPMSLKER QKFLVEGLPD VGPVMAENLL DNFNSVENIF
TASEEELKSV DGVGPITAKK IKEVVTKKYR E
//
