ID A9CGY3_AGRFC Unreviewed; 503 AA.
AC A9CGY3;
DT 15-JAN-2008, integrated into UniProtKB/TrEMBL.
DT 15-JAN-2008, sequence version 1.
DT 27-MAR-2024, entry version 76.
DE SubName: Full=Choline sulfatase {ECO:0000313|EMBL:AAK88799.1};
GN Name=betC {ECO:0000313|EMBL:AAK88799.1};
GN OrderedLocusNames=Atu4648 {ECO:0000313|EMBL:AAK88799.1};
OS Agrobacterium fabrum (strain C58 / ATCC 33970) (Agrobacterium tumefaciens
OS (strain C58)).
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Hyphomicrobiales;
OC Rhizobiaceae; Rhizobium/Agrobacterium group; Agrobacterium;
OC Agrobacterium tumefaciens complex.
OX NCBI_TaxID=176299 {ECO:0000313|EMBL:AAK88799.1, ECO:0000313|Proteomes:UP000000813};
RN [1] {ECO:0000313|EMBL:AAK88799.1, ECO:0000313|Proteomes:UP000000813}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=C58 / ATCC 33970 {ECO:0000313|Proteomes:UP000000813};
RX PubMed=11743193; DOI=10.1126/science.1066804;
RA Wood D.W., Setubal J.C., Kaul R., Monks D.E., Kitajima J.P., Okura V.K.,
RA Zhou Y., Chen L., Wood G.E., Almeida N.F.Jr., Woo L., Chen Y.,
RA Paulsen I.T., Eisen J.A., Karp P.D., Bovee D.Sr., Chapman P.,
RA Clendenning J., Deatherage G., Gillet W., Grant C., Kutyavin T., Levy R.,
RA Li M.J., McClelland E., Palmieri A., Raymond C., Rouse G.,
RA Saenphimmachak C., Wu Z., Romero P., Gordon D., Zhang S., Yoo H., Tao Y.,
RA Biddle P., Jung M., Krespan W., Perry M., Gordon-Kamm B., Liao L., Kim S.,
RA Hendrick C., Zhao Z.Y., Dolan M., Chumley F., Tingey S.V., Tomb J.F.,
RA Gordon M.P., Olson M.V., Nester E.W.;
RT "The genome of the natural genetic engineer Agrobacterium tumefaciens
RT C58.";
RL Science 294:2317-2323(2001).
RN [2] {ECO:0000313|EMBL:AAK88799.1, ECO:0000313|Proteomes:UP000000813}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=C58 / ATCC 33970 {ECO:0000313|Proteomes:UP000000813};
RX PubMed=11743194; DOI=10.1126/science.1066803;
RA Goodner B., Hinkle G., Gattung S., Miller N., Blanchard M., Qurollo B.,
RA Goldman B.S., Cao Y., Askenazi M., Halling C., Mullin L., Houmiel K.,
RA Gordon J., Vaudin M., Iartchouk O., Epp A., Liu F., Wollam C., Allinger M.,
RA Doughty D., Scott C., Lappas C., Markelz B., Flanagan C., Crowell C.,
RA Gurson J., Lomo C., Sear C., Strub G., Cielo C., Slater S.;
RT "Genome sequence of the plant pathogen and biotechnology agent
RT Agrobacterium tumefaciens C58.";
RL Science 294:2323-2328(2001).
CC -!- SIMILARITY: Belongs to the sulfatase family.
CC {ECO:0000256|ARBA:ARBA00008779}.
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DR EMBL; AE007870; AAK88799.1; -; Genomic_DNA.
DR PIR; AD3128; AD3128.
DR PIR; E98159; E98159.
DR RefSeq; NP_356014.1; NC_003063.2.
DR RefSeq; WP_010974043.1; NC_003063.2.
DR AlphaFoldDB; A9CGY3; -.
DR STRING; 176299.Atu4648; -.
DR EnsemblBacteria; AAK88799; AAK88799; Atu4648.
DR KEGG; atu:Atu4648; -.
DR PATRIC; fig|176299.10.peg.4453; -.
DR eggNOG; COG3119; Bacteria.
DR HOGENOM; CLU_006332_9_1_5; -.
DR OrthoDB; 9795675at2; -.
DR PhylomeDB; A9CGY3; -.
DR BioCyc; AGRO:ATU4648-MONOMER; -.
DR Proteomes; UP000000813; Chromosome linear.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR CDD; cd16032; choline-sulfatase; 1.
DR Gene3D; 3.40.720.10; Alkaline Phosphatase, subunit A; 1.
DR InterPro; IPR017850; Alkaline_phosphatase_core_sf.
DR InterPro; IPR017785; Choline-sulfatase.
DR InterPro; IPR025863; Choline_sulf_C_dom.
DR InterPro; IPR024607; Sulfatase_CS.
DR InterPro; IPR000917; Sulfatase_N.
DR NCBIfam; TIGR03417; chol_sulfatase; 1.
DR PANTHER; PTHR45953; IDURONATE 2-SULFATASE; 1.
DR PANTHER; PTHR45953:SF1; IDURONATE 2-SULFATASE; 1.
DR Pfam; PF12411; Choline_sulf_C; 1.
DR Pfam; PF00884; Sulfatase; 1.
DR SUPFAM; SSF53649; Alkaline phosphatase-like; 1.
DR PROSITE; PS00149; SULFATASE_2; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Reference proteome {ECO:0000313|Proteomes:UP000000813}.
FT DOMAIN 4..345
FT /note="Sulfatase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00884"
FT DOMAIN 448..499
FT /note="Choline sulfatase enzyme C-terminal"
FT /evidence="ECO:0000259|Pfam:PF12411"
SQ SEQUENCE 503 AA; 56819 MW; 408D6AF3A2D421A2 CRC64;
MPRPNILILM ADQFNGTFFP DGPADFLHAP HLKALAERSV RFANTYTASP LCAPARASFM
SGQLPSRTRV YDNAAEFASD IPTYAHHLRA AGYYTGLSGK MHFVGPDQLH GFEERLTTDI
YPADFGWTPD YTKPGERIDW WYHNLGSVTG AGVAEITNQM EYDDEVAYHA TRKLYDLSRR
LDDRPWCLTV SFTHPHDPYV ARRKFWDLYE DCAALDPQSK AIAFEEQDPH SKRLLEACDH
EAFEITGEQI RRARRGYFAN ISYIDEKIGE ILDVLNATRM EDTIILFLSD HGDMLGERGL
WFKMCFFEGS ARVPLMIAAP GWQPALIDAP VSTLDVTPTL CGLAGLDITS LKRWTDGEDL
AALAAGTGGR GPVPMEYAAE GSITPLVAIR DGRYKLSVCE ADPPLLYDLE TDPQELTNLA
HDPAFSDVLS SLSAEMGRRW QLPVFDAAVR ESQARRWVVY KALRNGAYYP WDYQPLQKAS
ERYMRNHMDL NVLEENQRFP RGE
//
