ID A9CUI0_HOEPD Unreviewed; 403 AA.
AC A9CUI0;
DT 05-FEB-2008, integrated into UniProtKB/TrEMBL.
DT 05-FEB-2008, sequence version 1.
DT 27-MAR-2024, entry version 60.
DE SubName: Full=3-oxoacyl-(Acyl-carrier-protein) synthase {ECO:0000313|EMBL:EDQ35214.1};
DE EC=2.3.1.179 {ECO:0000313|EMBL:EDQ35214.1};
GN ORFNames=HPDFL43_18507 {ECO:0000313|EMBL:EDQ35214.1};
OS Hoeflea phototrophica (strain DSM 17068 / NCIMB 14078 / DFL-43).
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Hyphomicrobiales;
OC Phyllobacteriaceae; Hoeflea.
OX NCBI_TaxID=411684 {ECO:0000313|EMBL:EDQ35214.1, ECO:0000313|Proteomes:UP000004291};
RN [1] {ECO:0000313|EMBL:EDQ35214.1, ECO:0000313|Proteomes:UP000004291}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DFL-43 {ECO:0000313|EMBL:EDQ35214.1,
RC ECO:0000313|Proteomes:UP000004291};
RA Wagner-Dobler I., Ferriera S., Johnson J., Kravitz S., Beeson K.,
RA Sutton G., Rogers Y.-H., Friedman R., Frazier M., Venter J.C.;
RL Submitted (OCT-2007) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:EDQ35214.1, ECO:0000313|Proteomes:UP000004291}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DFL-43 {ECO:0000313|EMBL:EDQ35214.1,
RC ECO:0000313|Proteomes:UP000004291};
RA Fiebig A.;
RL Submitted (JUN-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP
CC synthases family. {ECO:0000256|ARBA:ARBA00008467,
CC ECO:0000256|RuleBase:RU003694}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EDQ35214.1}.
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DR EMBL; ABIA03000005; EDQ35214.1; -; Genomic_DNA.
DR RefSeq; WP_007199445.1; NZ_CM002917.1.
DR AlphaFoldDB; A9CUI0; -.
DR STRING; 411684.HPDFL43_18507; -.
DR eggNOG; COG0304; Bacteria.
DR HOGENOM; CLU_000022_69_2_5; -.
DR OrthoDB; 9808669at2; -.
DR Proteomes; UP000004291; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0004315; F:3-oxoacyl-[acyl-carrier-protein] synthase activity; IEA:UniProtKB-EC.
DR GO; GO:0006633; P:fatty acid biosynthetic process; IEA:InterPro.
DR CDD; cd00834; KAS_I_II; 1.
DR Gene3D; 3.40.47.10; -; 2.
DR InterPro; IPR000794; Beta-ketoacyl_synthase.
DR InterPro; IPR018201; Ketoacyl_synth_AS.
DR InterPro; IPR014031; Ketoacyl_synth_C.
DR InterPro; IPR014030; Ketoacyl_synth_N.
DR InterPro; IPR020841; PKS_Beta-ketoAc_synthase_dom.
DR InterPro; IPR016039; Thiolase-like.
DR PANTHER; PTHR11712:SF336; 3-OXOACYL-[ACYL-CARRIER-PROTEIN] SYNTHASE, MITOCHONDRIAL; 1.
DR PANTHER; PTHR11712; POLYKETIDE SYNTHASE-RELATED; 1.
DR Pfam; PF00109; ketoacyl-synt; 1.
DR Pfam; PF02801; Ketoacyl-synt_C; 1.
DR SMART; SM00825; PKS_KS; 1.
DR SUPFAM; SSF53901; Thiolase-like; 1.
DR PROSITE; PS00606; KS3_1; 1.
DR PROSITE; PS52004; KS3_2; 1.
PE 3: Inferred from homology;
KW Acyltransferase {ECO:0000313|EMBL:EDQ35214.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000004291};
KW Transferase {ECO:0000256|RuleBase:RU003694, ECO:0000313|EMBL:EDQ35214.1}.
FT DOMAIN 3..402
FT /note="Ketosynthase family 3 (KS3)"
FT /evidence="ECO:0000259|PROSITE:PS52004"
SQ SEQUENCE 403 AA; 42042 MW; 5F2B3B6BD127A22F CRC64;
MDHRRVVITG IGGICALGGN ATDIWTGMKQ GRDGCRPLTI EKRDLKTNIG FNIIDYPEDD
GIEKRQGMTM SWISRLAVIA AREAFAQSGL SMETTDPKRT GSIVGVGTFG TDALDESYID
IFLEKKKRTQ LFTVPKVMPS GPASHVSISL GLKGSVYGVS SACASGNHAF ASAVDQIRLG
RADVMLAGGA ELALVYGPLK AWESLRVLAR SACRPFSADR DGLVLGDGAA IVVLESYEHA
KARGADILAE IAGVGLSADA SDIVNPSVEG PATAIRNCLA DGALSASQIG YINAHGTATQ
ANDKTETQAI RDVLGADADA VSVSSTKSMH GHCLGASSAI ELIACINAVR EGVVPPTINY
TAPDPACDLD VTPNEARERK IDVAISNAFA FGGTNAVVGV KRI
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