ID A9CYS5_HOEPD Unreviewed; 295 AA.
AC A9CYS5;
DT 05-FEB-2008, integrated into UniProtKB/TrEMBL.
DT 05-FEB-2008, sequence version 1.
DT 24-JAN-2024, entry version 57.
DE SubName: Full=Putative ring-cleavage extradiol dioxygenase {ECO:0000313|EMBL:EDQ34627.1};
GN ORFNames=HPDFL43_00480 {ECO:0000313|EMBL:EDQ34627.1};
OS Hoeflea phototrophica (strain DSM 17068 / NCIMB 14078 / DFL-43).
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Hyphomicrobiales;
OC Phyllobacteriaceae; Hoeflea.
OX NCBI_TaxID=411684 {ECO:0000313|EMBL:EDQ34627.1, ECO:0000313|Proteomes:UP000004291};
RN [1] {ECO:0000313|EMBL:EDQ34627.1, ECO:0000313|Proteomes:UP000004291}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DFL-43 {ECO:0000313|EMBL:EDQ34627.1,
RC ECO:0000313|Proteomes:UP000004291};
RA Wagner-Dobler I., Ferriera S., Johnson J., Kravitz S., Beeson K.,
RA Sutton G., Rogers Y.-H., Friedman R., Frazier M., Venter J.C.;
RL Submitted (OCT-2007) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:EDQ34627.1, ECO:0000313|Proteomes:UP000004291}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DFL-43 {ECO:0000313|EMBL:EDQ34627.1,
RC ECO:0000313|Proteomes:UP000004291};
RA Fiebig A.;
RL Submitted (JUN-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=Fe(2+); Xref=ChEBI:CHEBI:29033;
CC Evidence={ECO:0000256|ARBA:ARBA00001954,
CC ECO:0000256|RuleBase:RU000683};
CC -!- SIMILARITY: Belongs to the extradiol ring-cleavage dioxygenase family.
CC {ECO:0000256|ARBA:ARBA00008784, ECO:0000256|RuleBase:RU000683}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EDQ34627.1}.
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DR EMBL; ABIA03000002; EDQ34627.1; -; Genomic_DNA.
DR RefSeq; WP_007195888.1; NZ_CM002917.1.
DR AlphaFoldDB; A9CYS5; -.
DR STRING; 411684.HPDFL43_00480; -.
DR eggNOG; COG2514; Bacteria.
DR HOGENOM; CLU_059557_0_0_5; -.
DR OrthoDB; 9792626at2; -.
DR Proteomes; UP000004291; Chromosome.
DR GO; GO:0051213; F:dioxygenase activity; IEA:UniProtKB-KW.
DR GO; GO:0008198; F:ferrous iron binding; IEA:InterPro.
DR GO; GO:0019439; P:aromatic compound catabolic process; IEA:UniProtKB-KW.
DR Gene3D; 3.10.180.10; 2,3-Dihydroxybiphenyl 1,2-Dioxygenase, domain 1; 1.
DR InterPro; IPR029068; Glyas_Bleomycin-R_OHBP_Dase.
DR InterPro; IPR004360; Glyas_Fos-R_dOase_dom.
DR InterPro; IPR037523; VOC.
DR InterPro; IPR000486; Xdiol_ring_cleave_dOase_1/2.
DR PANTHER; PTHR43279; CATECHOL-2,3-DIOXYGENASE; 1.
DR PANTHER; PTHR43279:SF1; CATECHOL-2,3-DIOXYGENASE; 1.
DR Pfam; PF00903; Glyoxalase; 1.
DR SUPFAM; SSF54593; Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase; 2.
DR PROSITE; PS00082; EXTRADIOL_DIOXYGENAS; 1.
DR PROSITE; PS51819; VOC; 1.
PE 3: Inferred from homology;
KW Aromatic hydrocarbons catabolism {ECO:0000256|ARBA:ARBA00022797,
KW ECO:0000256|RuleBase:RU000683};
KW Dioxygenase {ECO:0000256|ARBA:ARBA00022964, ECO:0000256|RuleBase:RU000683};
KW Iron {ECO:0000256|RuleBase:RU000683};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW ECO:0000256|RuleBase:RU000683};
KW Reference proteome {ECO:0000313|Proteomes:UP000004291}.
FT DOMAIN 20..134
FT /note="VOC"
FT /evidence="ECO:0000259|PROSITE:PS51819"
SQ SEQUENCE 295 AA; 32108 MW; 07F1D66D1514F4F6 CRC64;
MLNSVHLTKT NLSPQYDRVS WGVVELQVTD LDRAIEFWSS ALGLIERDQS ASGIALGTRD
RTLIVLHSGA DTPVAAPYTG MYHVAIGVRS QAEFSRMLAR LIQLNVQVGP TDHLMAKSLY
LQDPDGLEIE ITYETPERFG HFGDMSKGLT LYSVNGEAHS GRGPLDVRAE LSHAAGTDPM
APLADDSYLA HLHFKVPALE PALEWYETLG FERHLTLDAW GFADMGAGAP NTHRLAMNIW
AGPNNPPMPQ GMAGLVHYEL ITHSEIVASP HLRQDGDALR GTDPAGVAVT LRSAK
//
