ID A9D2J5_HOEPD Unreviewed; 492 AA.
AC A9D2J5;
DT 05-FEB-2008, integrated into UniProtKB/TrEMBL.
DT 05-FEB-2008, sequence version 1.
DT 27-MAR-2024, entry version 70.
DE SubName: Full=Transcriptional regulator {ECO:0000313|EMBL:EDQ34219.1};
GN ORFNames=HPDFL43_14517 {ECO:0000313|EMBL:EDQ34219.1};
OS Hoeflea phototrophica (strain DSM 17068 / NCIMB 14078 / DFL-43).
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Hyphomicrobiales;
OC Phyllobacteriaceae; Hoeflea.
OX NCBI_TaxID=411684 {ECO:0000313|EMBL:EDQ34219.1, ECO:0000313|Proteomes:UP000004291};
RN [1] {ECO:0000313|EMBL:EDQ34219.1, ECO:0000313|Proteomes:UP000004291}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DFL-43 {ECO:0000313|EMBL:EDQ34219.1,
RC ECO:0000313|Proteomes:UP000004291};
RA Wagner-Dobler I., Ferriera S., Johnson J., Kravitz S., Beeson K.,
RA Sutton G., Rogers Y.-H., Friedman R., Frazier M., Venter J.C.;
RL Submitted (OCT-2007) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:EDQ34219.1, ECO:0000313|Proteomes:UP000004291}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DFL-43 {ECO:0000313|EMBL:EDQ34219.1,
RC ECO:0000313|Proteomes:UP000004291};
RA Fiebig A.;
RL Submitted (JUN-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: In the C-terminal section; belongs to the class-I
CC pyridoxal-phosphate-dependent aminotransferase family.
CC {ECO:0000256|ARBA:ARBA00005384}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EDQ34219.1}.
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DR EMBL; ABIA03000004; EDQ34219.1; -; Genomic_DNA.
DR RefSeq; WP_007198665.1; NZ_CM002917.1.
DR AlphaFoldDB; A9D2J5; -.
DR STRING; 411684.HPDFL43_14517; -.
DR eggNOG; COG1167; Bacteria.
DR HOGENOM; CLU_017584_0_1_5; -.
DR OrthoDB; 9808770at2; -.
DR Proteomes; UP000004291; Chromosome.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
DR GO; GO:0009058; P:biosynthetic process; IEA:InterPro.
DR CDD; cd00609; AAT_like; 1.
DR CDD; cd07377; WHTH_GntR; 1.
DR Gene3D; 3.40.640.10; Type I PLP-dependent aspartate aminotransferase-like (Major domain); 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR004839; Aminotransferase_I/II.
DR InterPro; IPR015424; PyrdxlP-dep_Trfase.
DR InterPro; IPR015421; PyrdxlP-dep_Trfase_major.
DR InterPro; IPR000524; Tscrpt_reg_HTH_GntR.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR46577; HTH-TYPE TRANSCRIPTIONAL REGULATORY PROTEIN GABR; 1.
DR PANTHER; PTHR46577:SF1; HTH-TYPE TRANSCRIPTIONAL REGULATORY PROTEIN GABR; 1.
DR Pfam; PF00155; Aminotran_1_2; 1.
DR Pfam; PF00392; GntR; 1.
DR PRINTS; PR00035; HTHGNTR.
DR SMART; SM00345; HTH_GNTR; 1.
DR SUPFAM; SSF53383; PLP-dependent transferases; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS50949; HTH_GNTR; 1.
PE 3: Inferred from homology;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Pyridoxal phosphate {ECO:0000256|ARBA:ARBA00022898};
KW Reference proteome {ECO:0000313|Proteomes:UP000004291};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 20..88
FT /note="HTH gntR-type"
FT /evidence="ECO:0000259|PROSITE:PS50949"
SQ SEQUENCE 492 AA; 53029 MW; 16967EB4F7EFAE04 CRC64;
MKIKAGAILS SIRIDRSSDR KISVQLYMGL RDIILSGGLN GGERLPATRT LASELGVSRT
TALDAVDRLV SEGLLESRIG AGTFVSHTLK DRVPSSARTA GPEPKQPLRL SPTAVQANRL
FADRRQLPHK SQAFVTALPA LNAFPMAQWA RLSARHLRSD RDAVMGYGNS FGHPRLRAAI
ASHLNATRGI QCDPEQVFIT GGAQQAFSVI GSMLLDRGEK VWFENPGAIG ARNAFIACGA
DLVPVAVDDE GINVADGLAK APDFRLAFVT PSHQQPLSRV LSLSRRLALL NAAETANAFI
IEDDYDGDFY FGDQPLPTLK SIDTNGRVIY VGTFSKTLFP SLRLGYLVAP QNMADAVSGI
FSAALGGVAT WPQAVVADFI DEGHFATHIR TMRNHYKQQH EALHHHALGL DTSLQIQRAS
AGFHTVGFFN EPGRKEEAFV SAAAERGLTL SGIGRYCLEP IERKGVVIGY GAASEAEIRS
GVETLNALLE QT
//
