ID A9DRF1_9FLAO Unreviewed; 616 AA.
AC A9DRF1;
DT 05-FEB-2008, integrated into UniProtKB/TrEMBL.
DT 05-FEB-2008, sequence version 1.
DT 27-MAR-2024, entry version 76.
DE SubName: Full=Sodium/hydrogen exchanger {ECO:0000313|EMBL:EDP96784.1};
GN ORFNames=KAOT1_16513 {ECO:0000313|EMBL:EDP96784.1};
OS Kordia algicida OT-1.
OC Bacteria; Bacteroidota; Flavobacteriia; Flavobacteriales;
OC Flavobacteriaceae; Kordia.
OX NCBI_TaxID=391587 {ECO:0000313|EMBL:EDP96784.1, ECO:0000313|Proteomes:UP000002945};
RN [1] {ECO:0000313|EMBL:EDP96784.1, ECO:0000313|Proteomes:UP000002945}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=OT-1 {ECO:0000313|EMBL:EDP96784.1,
RC ECO:0000313|Proteomes:UP000002945};
RX PubMed=21622754; DOI=10.1128/JB.05241-11;
RA Lee H.S., Kang S.G., Kwon K.K., Lee J.H., Kim S.J.;
RT "Genome sequence of the algicidal bacterium Kordia algicida OT-1.";
RL J. Bacteriol. 193:4031-4032(2011).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EDP96784.1}.
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DR EMBL; ABIB01000003; EDP96784.1; -; Genomic_DNA.
DR RefSeq; WP_007095838.1; NZ_DS544873.1.
DR AlphaFoldDB; A9DRF1; -.
DR STRING; 391587.KAOT1_16513; -.
DR eggNOG; COG0025; Bacteria.
DR eggNOG; COG0569; Bacteria.
DR HOGENOM; CLU_005912_10_1_10; -.
DR OrthoDB; 570124at2; -.
DR Proteomes; UP000002945; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015297; F:antiporter activity; IEA:InterPro.
DR GO; GO:0006813; P:potassium ion transport; IEA:InterPro.
DR GO; GO:1902600; P:proton transmembrane transport; IEA:InterPro.
DR Gene3D; 1.20.1530.20; -; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR006153; Cation/H_exchanger.
DR InterPro; IPR038770; Na+/solute_symporter_sf.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR003148; RCK_N.
DR PANTHER; PTHR32507; NA(+)/H(+) ANTIPORTER 1; 1.
DR PANTHER; PTHR32507:SF0; NA(+)_H(+) ANTIPORTER 2-RELATED; 1.
DR Pfam; PF00999; Na_H_Exchanger; 1.
DR Pfam; PF02254; TrkA_N; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000002945};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 21..41
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 70..89
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 101..124
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 130..150
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 162..184
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 204..224
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 231..250
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 256..272
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 284..303
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 315..333
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 345..366
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 378..402
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 8..400
FT /note="Cation/H+ exchanger"
FT /evidence="ECO:0000259|Pfam:PF00999"
FT DOMAIN 415..490
FT /note="RCK N-terminal"
FT /evidence="ECO:0000259|Pfam:PF02254"
SQ SEQUENCE 616 AA; 67839 MW; A78E743F5D43D1B7 CRC64;
MLELAGIIIL GILAQWVAWK FKIPAILPLI LIGLLVGPIA AEFLSEDGTK WIEPIWDNEK
EKGLFPGESL YYFVSLAISI ILFEGGLTLK RAEIKNVGPV ITKLITLGSA ITFFGAGIVA
HLVFGLSWEL SFLFSGLIIV TGPTVITPIL RNIPLKKDIS TVLKWEGILI DPIGALVAVL
VFEFISVEGD SGFTKTALIE FGKIILFGTT FGFTFAHALA FAINKKFIPH YLLNVVSLSA
VLLVFVESEI FAHESGLLAV VVMGMVLGNG KLENIKELLY FKESLSVLLI SILFILLSAN
IDMNDLMLLY NWKTAALFVL VVFIIRPLGV FLSTANSKLK TNEKLFISWV GPRGIVAAGI
ASLFGSKLVN EGVPGAEYIT PLVFMIVLGT VLLNATTARL FAKLVGVFLK KSNGILIVGA
SKISRLLGHY LETNGRHVVL IDSNQSNIAK ARELGLEAIN TDIYSNTLTD NIELNDVGYL
MAMTGNSGIN KYAIDKFGAE FGENGSFRLV TREEMLDENN NPKEGLFSNT DDYVTLSAVT
RKYPSIQEID INDEEHYRGL IEITNNDKDI IPLFIKKEDN EFYIISSHNT EVDKIGENWK
LVYLGKPFDV EETETN
//
