ID A9FXQ2_SORC5 Unreviewed; 344 AA.
AC A9FXQ2;
DT 05-FEB-2008, integrated into UniProtKB/TrEMBL.
DT 05-FEB-2008, sequence version 1.
DT 27-MAR-2024, entry version 78.
DE SubName: Full=GutB protein {ECO:0000313|EMBL:CAN95537.1};
GN Name=gutB {ECO:0000313|EMBL:CAN95537.1};
GN OrderedLocusNames=sce5374 {ECO:0000313|EMBL:CAN95537.1};
OS Sorangium cellulosum (strain So ce56) (Polyangium cellulosum (strain So
OS ce56)).
OC Bacteria; Myxococcota; Polyangia; Polyangiales; Polyangiaceae; Sorangium.
OX NCBI_TaxID=448385 {ECO:0000313|EMBL:CAN95537.1, ECO:0000313|Proteomes:UP000002139};
RN [1] {ECO:0000313|EMBL:CAN95537.1, ECO:0000313|Proteomes:UP000002139}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=So ce56 {ECO:0000313|Proteomes:UP000002139};
RX PubMed=17965706; DOI=10.1038/nbt1354;
RA Schneiker S., Perlova O., Kaiser O., Gerth K., Alici A., Altmeyer M.O.,
RA Bartels D., Bekel T., Beyer S., Bode E., Bode H.B., Bolten C.J.,
RA Choudhuri J.V., Doss S., Elnakady Y.A., Frank B., Gaigalat L., Goesmann A.,
RA Groeger C., Gross F., Jelsbak L., Jelsbak L., Kalinowski J., Kegler C.,
RA Knauber T., Konietzny S., Kopp M., Krause L., Krug D., Linke B., Mahmud T.,
RA Martinez-Arias R., McHardy A.C., Merai M., Meyer F., Mormann S.,
RA Munoz-Dorado J., Perez J., Pradella S., Rachid S., Raddatz G., Rosenau F.,
RA Rueckert C., Sasse F., Scharfe M., Schuster S.C., Suen G.,
RA Treuner-Lange A., Velicer G.J., Vorholter F.-J., Weissman K.J., Welch R.D.,
RA Wenzel S.C., Whitworth D.E., Wilhelm S., Wittmann C., Bloecker H.,
RA Puehler A., Mueller R.;
RT "Complete genome sequence of the myxobacterium Sorangium cellulosum.";
RL Nat. Biotechnol. 25:1281-1289(2007).
CC -!- COFACTOR:
CC Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC Evidence={ECO:0000256|ARBA:ARBA00001947};
CC -!- SIMILARITY: Belongs to the zinc-containing alcohol dehydrogenase
CC family. {ECO:0000256|ARBA:ARBA00008072}.
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DR EMBL; AM746676; CAN95537.1; -; Genomic_DNA.
DR RefSeq; WP_012238005.1; NC_010162.1.
DR AlphaFoldDB; A9FXQ2; -.
DR STRING; 448385.sce5374; -.
DR KEGG; scl:sce5374; -.
DR eggNOG; COG1063; Bacteria.
DR HOGENOM; CLU_026673_11_5_7; -.
DR OrthoDB; 9774952at2; -.
DR BioCyc; SCEL448385:SCE_RS27570-MONOMER; -.
DR Proteomes; UP000002139; Chromosome.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR Gene3D; 3.90.180.10; Medium-chain alcohol dehydrogenases, catalytic domain; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR013149; ADH-like_C.
DR InterPro; IPR013154; ADH-like_N.
DR InterPro; IPR011032; GroES-like_sf.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR PANTHER; PTHR43161; SORBITOL DEHYDROGENASE; 1.
DR PANTHER; PTHR43161:SF9; SORBITOL DEHYDROGENASE; 1.
DR Pfam; PF08240; ADH_N; 1.
DR Pfam; PF00107; ADH_zinc_N; 1.
DR SUPFAM; SSF50129; GroES-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 3: Inferred from homology;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000002139};
KW Zinc {ECO:0000256|ARBA:ARBA00022833}.
FT DOMAIN 25..134
FT /note="Alcohol dehydrogenase-like N-terminal"
FT /evidence="ECO:0000259|Pfam:PF08240"
FT DOMAIN 174..297
FT /note="Alcohol dehydrogenase-like C-terminal"
FT /evidence="ECO:0000259|Pfam:PF00107"
SQ SEQUENCE 344 AA; 36955 MW; FE43AEA395A47DE6 CRC64;
MRATFIHGIR DVRLGEVEPP RPREGMVTIQ VAGCGICGSD LHYYLEGGIG AAQVRDPFVP
GHEFAGWVVD DHPALGLSRG QLVAVDPAHA CGRCEWCHRG HVNLCPHVEF LGAPPLHGGM
AERLAVRPEQ LVPVPRDFSV RKAVMLEPLG VAIHAMDLAR PHLQETVAVL GCGPIALCLV
QLARLAGVER VFAIDPVAYR AEAARRLGAH DAAPTFAAIA EWTGGRGVDL VIEATNSPEG
FHHAAEAARI GGRILLAGIP EGDRYSLPAA LCRRKGLKIK FSRRMGHVYP RAIRLVAEGA
VDVESIVTHR FDLSEAENGF RLQADCQDGA LKSIIVPGEG DTPF
//
