ID A9M6E9_BRUC2 Unreviewed; 558 AA.
AC A9M6E9;
DT 05-FEB-2008, integrated into UniProtKB/TrEMBL.
DT 05-FEB-2008, sequence version 1.
DT 27-MAR-2024, entry version 72.
DE SubName: Full=Na+ cotransporter {ECO:0000313|EMBL:ABX62545.1};
GN OrderedLocusNames=BCAN_A1519 {ECO:0000313|EMBL:ABX62545.1};
OS Brucella canis (strain ATCC 23365 / NCTC 10854).
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Hyphomicrobiales;
OC Brucellaceae; Brucella/Ochrobactrum group; Brucella.
OX NCBI_TaxID=483179 {ECO:0000313|EMBL:ABX62545.1, ECO:0000313|Proteomes:UP000001385};
RN [1] {ECO:0000313|EMBL:ABX62545.1, ECO:0000313|Proteomes:UP000001385}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 23365 / NCTC 10854 {ECO:0000313|Proteomes:UP000001385};
RA Setubal J.C., Bowns C., Boyle S., Crasta O.R., Czar M.J., Dharmanolla C.,
RA Gillespie J.J., Kenyon R.W., Lu J., Mane S., Mohapatra S., Nagrani S.,
RA Purkayastha A., Rajasimha H.K., Shallom J.M., Shallom S., Shukla M.,
RA Snyder E.E., Sobral B.W., Wattam A.R., Will R., Williams K., Yoo H.,
RA Bruce D., Detter C., Munk C., Brettin T.S.;
RT "Brucella canis ATCC 23365 whole genome shotgun sequencing project.";
RL Submitted (OCT-2007) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; CP000872; ABX62545.1; -; Genomic_DNA.
DR RefSeq; WP_004691568.1; NC_010103.1.
DR AlphaFoldDB; A9M6E9; -.
DR GeneID; 55591129; -.
DR KEGG; bcs:BCAN_A1519; -.
DR HOGENOM; CLU_025623_2_1_5; -.
DR Proteomes; UP000001385; Chromosome I.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005436; F:sodium:phosphate symporter activity; IEA:InterPro.
DR GO; GO:0044341; P:sodium-dependent phosphate transport; IEA:InterPro.
DR InterPro; IPR003841; Na/Pi_transpt.
DR InterPro; IPR038078; PhoU-like_sf.
DR InterPro; IPR026022; PhoU_dom.
DR NCBIfam; NF037997; Na_Pi_symport; 1.
DR PANTHER; PTHR10010:SF46; SODIUM_PHOSPHATE COTRANSPORTER-RELATED; 1.
DR PANTHER; PTHR10010; SOLUTE CARRIER FAMILY 34 SODIUM PHOSPHATE , MEMBER 2-RELATED; 1.
DR Pfam; PF02690; Na_Pi_cotrans; 2.
DR Pfam; PF01895; PhoU; 2.
DR SUPFAM; SSF109755; PhoU-like; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 6..24
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 44..61
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 102..124
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 175..199
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 211..231
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 243..263
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 283..301
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 352..429
FT /note="PhoU"
FT /evidence="ECO:0000259|Pfam:PF01895"
FT DOMAIN 455..537
FT /note="PhoU"
FT /evidence="ECO:0000259|Pfam:PF01895"
SQ SEQUENCE 558 AA; 61327 MW; 5E432732749D46E8 CRC64;
MNGSLVLLHL AGAVALLLWA TRMVRTGVER AYGDRLRRRL RNQMQNPLLS VAFGLALSIA
LQSSTAVTLL VGSFVGSGFV SGVAGLMAVR GGELGSALVV KILSYDLTLL VPLCLVVGTG
IFMTTERRDW RQIGRILVGI GLLIMSLEMT GQATEPLRRS ELLPVIVDYL SSDPVTAYLL
AALMTWLFHS SVAAVILLTT FASRGLIHPE LAVVMVLGVN LGSSIIAPIL TRHAPPETRV
VPLGNLLMRG AGSLIMLVLY QTFKPSVGFL GSDPVSQVVN AHILFNVLVM IAGIPLSGLV
LRATEALVHL NADKDAPAKP MAVEEYSALD NAVLDRPSQA LANATREVVG VCDTIEVMLR
RIIELYEKPD QARINELEAL DDRVDKKHVA IKLYLTRLAT QNLTDFESLR MQELLGACVK
LEQVGDIIVR NMVAQVQKKM NHKLEFTEEG WKELSHFHAM VLANAHMAFN VIVSRDGRTA
RQLVQEKDRL REMEKQTSMR HFSRLREGST RSIETSSIHL DTIRDLKQIN SLLASMAYPV
LEEQGLLSDT RLKTAKQS
//
