ID A9MHZ4_SALAR Unreviewed; 1295 AA.
AC A9MHZ4;
DT 05-FEB-2008, integrated into UniProtKB/TrEMBL.
DT 05-FEB-2008, sequence version 1.
DT 27-MAR-2024, entry version 94.
DE RecName: Full=DNA translocase FtsK {ECO:0000256|ARBA:ARBA00020887};
GN OrderedLocusNames=SARI_02004 {ECO:0000313|EMBL:ABX21884.1};
OS Salmonella arizonae (strain ATCC BAA-731 / CDC346-86 / RSK2980).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Salmonella.
OX NCBI_TaxID=41514 {ECO:0000313|EMBL:ABX21884.1, ECO:0000313|Proteomes:UP000002084};
RN [1] {ECO:0000313|EMBL:ABX21884.1, ECO:0000313|Proteomes:UP000002084}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-731 / CDC346-86 / RSK2980
RC {ECO:0000313|Proteomes:UP000002084};
RG The Salmonella enterica serovar Arizonae Genome Sequencing Project;
RA McClelland M., Sanderson E.K., Porwollik S., Spieth J., Clifton W.S.,
RA Fulton R., Chunyan W., Wollam A., Shah N., Pepin K., Bhonagiri V., Nash W.,
RA Johnson M., Thiruvilangam P., Wilson R.;
RL Submitted (NOV-2007) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the FtsK/SpoIIIE/SftA family.
CC {ECO:0000256|ARBA:ARBA00006474}.
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DR EMBL; CP000880; ABX21884.1; -; Genomic_DNA.
DR STRING; 41514.SARI_02004; -.
DR KEGG; ses:SARI_02004; -.
DR HOGENOM; CLU_001981_0_1_6; -.
DR Proteomes; UP000002084; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR GO; GO:0007059; P:chromosome segregation; IEA:UniProtKB-KW.
DR CDD; cd01127; TrwB_TraG_TraD_VirD4; 1.
DR Gene3D; 3.30.980.40; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR025199; FtsK_4TM.
DR InterPro; IPR041027; FtsK_alpha.
DR InterPro; IPR002543; FtsK_dom.
DR InterPro; IPR018541; Ftsk_gamma.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR22683:SF41; DNA TRANSLOCASE FTSK; 1.
DR PANTHER; PTHR22683; SPORULATION PROTEIN RELATED; 1.
DR Pfam; PF13491; FtsK_4TM; 1.
DR Pfam; PF17854; FtsK_alpha; 1.
DR Pfam; PF09397; FtsK_gamma; 1.
DR Pfam; PF01580; FtsK_SpoIIIE; 1.
DR SMART; SM00843; Ftsk_gamma; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS50901; FTSK; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU00289}; Cell cycle {ECO:0000256|ARBA:ARBA00023306};
KW Cell division {ECO:0000256|ARBA:ARBA00022618};
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU00289}; Reference proteome {ECO:0000313|Proteomes:UP000002084};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 42..61
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 92..115
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 127..148
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 154..175
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 182..201
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 941..1154
FT /note="FtsK"
FT /evidence="ECO:0000259|PROSITE:PS50901"
FT REGION 373..482
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 663..719
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 732..816
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1209..1229
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 460..474
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 676..691
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 696..710
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 764..782
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT BINDING 958..965
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00289"
SQ SEQUENCE 1295 AA; 141285 MW; F1AF019294BF7915 CRC64;
MSVLASGGKS LEPGEPFLSQ EYTEDKDVTL TKLSSGRRLL EALLILIALF AVWLMAALLS
FNPSDPSWSQ TAWHEPIHNL GGAPGAWLAD TLFFIFGVMA YTIPVIIVGG CWFAWRHQST
DDYIDYFAVS LRLIGVLALI LTSCGLAAIN ADDIWYFASG GVIGSLLSTT LQPLLHSSGG
TITLLCIWAA GLTLFTGWSW VSIAEKLGGW LLNILTFASN RTRRDDTWVD DEEYEDEYDE
ETDGVQRESR RARILRGALA RRKRLAAKFS NPRGRQTDAA LFSGKRMDDG EDIQYSARGV
AADPDDVLFS GNRATQPEYD EYDPLLNGHS VAEPVAAAAA ATAVTQTWAT SADPVTQTPS
MPEAVVAQPT VEWQPVPGPQ TGEPVIAPAP EGYPSHPQYA QPQAAQDAPW QQPAPVASAP
KYAVSPAIAA EYESPAPQET QPQRQAPGVE QHWQPEPTHQ PTPVYQPDPV AAEPSHIPPV
VEQPVVTEPE PVIEETRPAR PPLYYFEEVE EKRAREREQL AAWYQPIPEP IKETAPVKAA
APVKPSVSAA PSIPPVEAVA AAAGIKSGAL AAGAAAAAPA FGLATSGAPR PQVKEGIGPQ
LPRPNRVRVP TRRELASYGI KLPSQRIAEE KAREAERYQY ETGAQLTDEE IDAMHQDELA
RQFAQSQQHR YGEAYQHDTQ QAEDDDTAAE AELARQFAAS QQQRYSGEQP AGAQPFSLDN
LDFSPMKILV DEGPHEPLFT PGVMPESAPI QQPVAPQPQY QQPQQPVAPQ SQYQQPQQPA
APQDSLIHPL LMRNGDSRPL QRPTTPLPSL DLLTPPPSEV EPVDTFALEQ MARLVEARLA
DFRIKADVVN YSPGPVITRF ELNLAPGVKA ARISNLSRDL ARSLSTVAVR VVEVIPGKPY
VGLELPNKKR QTVYLREVLD NAKFRDNPSP LTVVLGKDIA GDPVVADLAK MPHLLVAGTT
GSGKSVGVNA MILSMLYKAQ PEDVRFIMID PKMLELSVYE GIPHLLTEVV TDMKDAANAL
RWSVNEMERR YKLMSALGVR NLAGYNEKIA EAARMGRPIP DPYWKPGDSM DVQHPVLEKL
PYIVVLVDEF ADLMMTVGKK VEELIARLAQ KARAAGIHLV LATQRPSVDV ITGLIKANIP
TRIAFTVSSK IDSRTILDQG GAESLLGMGD MLFSGPNSTM PVRVHGAFVR DQEVHAVVQD
WKARGRPQYV DGITSDSESE GGGSFDGGEE LDPLFDQAVN FVTQKRKASI SGVQRQFRIG
YNRAARIIEQ MEAQGIVSAQ GHNGNREVLA PPPFE
//
