ID   A9NK43_PICSI            Unreviewed;       115 AA.
AC   A9NK43;
DT   05-FEB-2008, integrated into UniProtKB/TrEMBL.
DT   05-FEB-2008, sequence version 1.
DT   24-JAN-2024, entry version 53.
DE   RecName: Full=Glutaredoxin domain-containing protein {ECO:0000259|Pfam:PF00462};
OS   Picea sitchensis (Sitka spruce) (Pinus sitchensis).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Pinopsida; Pinidae; Conifers I; Pinales; Pinaceae; Picea.
OX   NCBI_TaxID=3332 {ECO:0000313|EMBL:ABK21004.1};
RN   [1] {ECO:0000313|EMBL:ABK21004.1}
RP   NUCLEOTIDE SEQUENCE.
RC   TISSUE=Bark {ECO:0000313|EMBL:ABK25537.1}, and Green portion of the
RC   leader tissue {ECO:0000313|EMBL:ABK21004.1};
RX   PubMed=18854048; DOI=10.1186/1471-2164-9-484;
RA   Ralph S.G., Chun H.J., Kolosova N., Cooper D., Oddy C., Ritland C.E.,
RA   Kirkpatrick R., Moore R., Barber S., Holt R.A., Jones S.J., Marra M.A.,
RA   Douglas C.J., Ritland K., Bohlmann J.;
RT   "A conifer genomics resource of 200,000 spruce (Picea spp.) ESTs and 6,464
RT   high-quality, sequence-finished full-length cDNAs for Sitka spruce (Picea
RT   sitchensis).";
RL   BMC Genomics 9:484-484(2008).
RN   [2] {ECO:0000313|EMBL:ACN40885.1}
RP   NUCLEOTIDE SEQUENCE.
RC   TISSUE=Bark {ECO:0000313|EMBL:ACN40885.1};
RA   Reid K.E., Liao N., Ralph S., Kolosova N., Oddy C., Moore R., Mayo M.,
RA   Wagner S., King J., Yanchuk A., Holt R., Jones S., Marra M., Ritland C.E.,
RA   Ritland K., Bohlmann J.;
RT   "Full length sequence-verified cDNA sequences from Sitka spruce (Picea
RT   sitchensis).";
RL   Submitted (FEB-2009) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Has a glutathione-disulfide oxidoreductase activity in the
CC       presence of NADPH and glutathione reductase. Reduces low molecular
CC       weight disulfides and proteins. {ECO:0000256|ARBA:ARBA00002549}.
CC   -!- SIMILARITY: Belongs to the glutaredoxin family. CPYC subfamily.
CC       {ECO:0000256|ARBA:ARBA00007190}.
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DR   EMBL; EF081616; ABK21004.1; -; mRNA.
DR   EMBL; EF085643; ABK24946.1; -; mRNA.
DR   EMBL; EF086256; ABK25537.1; -; mRNA.
DR   EMBL; BT071425; ACN40885.1; -; mRNA.
DR   AlphaFoldDB; A9NK43; -.
DR   CDD; cd03419; GRX_GRXh_1_2_like; 1.
DR   Gene3D; 3.40.30.10; Glutaredoxin; 1.
DR   InterPro; IPR011767; GLR_AS.
DR   InterPro; IPR002109; Glutaredoxin.
DR   InterPro; IPR011899; Glutaredoxin_euk/vir.
DR   InterPro; IPR014025; Glutaredoxin_subgr.
DR   InterPro; IPR036249; Thioredoxin-like_sf.
DR   NCBIfam; TIGR02180; GRX_euk; 1.
DR   PANTHER; PTHR45694; GLUTAREDOXIN 2; 1.
DR   PANTHER; PTHR45694:SF14; GLUTAREDOXIN-C2; 1.
DR   Pfam; PF00462; Glutaredoxin; 1.
DR   PRINTS; PR00160; GLUTAREDOXIN.
DR   SUPFAM; SSF52833; Thioredoxin-like; 1.
DR   PROSITE; PS00195; GLUTAREDOXIN_1; 1.
DR   PROSITE; PS51354; GLUTAREDOXIN_2; 1.
PE   2: Evidence at transcript level;
KW   Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW   Electron transport {ECO:0000256|ARBA:ARBA00022982};
KW   Redox-active center {ECO:0000256|ARBA:ARBA00023284};
KW   Transport {ECO:0000256|ARBA:ARBA00022448}.
FT   DOMAIN          28..90
FT                   /note="Glutaredoxin"
FT                   /evidence="ECO:0000259|Pfam:PF00462"
SQ   SEQUENCE   115 AA;  12116 MW;  24F13CFC1D38D3BE CRC64;
     MGGSTSKNPQ IIEMAMGKAK EIVSSNSVVV FSKTYCPYCT QVKQLLSSLG AKTKVVELDT
     ESDGKEIQTA LQEWTGQRTV PSVFIGGTHI GGCDDTVAKH NSGKLVPLLT EAGGV
//