ID A9QMR7_9BILA Unreviewed; 614 AA.
AC A9QMR7;
DT 05-FEB-2008, integrated into UniProtKB/TrEMBL.
DT 05-FEB-2008, sequence version 1.
DT 27-MAR-2024, entry version 36.
DE RecName: Full=DNA-directed RNA polymerase {ECO:0000256|ARBA:ARBA00012418};
DE EC=2.7.7.6 {ECO:0000256|ARBA:ARBA00012418};
DE Flags: Fragment;
OS Bunonema reticulatum.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Bunonematomorpha; Bunonematoidea; Bunonematidae; Bunonema.
OX NCBI_TaxID=288523 {ECO:0000313|EMBL:ABV83178.1};
RN [1] {ECO:0000313|EMBL:ABV83178.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=PDL1002 {ECO:0000313|EMBL:ABV83178.1};
RX PubMed=18024125; DOI=10.1016/j.cub.2007.10.061;
RA Kiontke K., Barriere A., Kolotuev I., Podbilewicz B., Sommer R.,
RA Fitch D.H., Felix M.A.;
RT "Trends, stasis, and drift in the evolution of nematode vulva
RT development.";
RL Curr. Biol. 17:1925-1937(2007).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate +
CC RNA(n+1); Xref=Rhea:RHEA:21248, Rhea:RHEA-COMP:14527, Rhea:RHEA-
CC COMP:17342, ChEBI:CHEBI:33019, ChEBI:CHEBI:61557, ChEBI:CHEBI:140395;
CC EC=2.7.7.6; Evidence={ECO:0000256|ARBA:ARBA00024550};
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DR EMBL; EU161972; ABV83178.1; -; Genomic_DNA.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0003899; F:DNA-directed 5'-3' RNA polymerase activity; IEA:UniProtKB-EC.
DR GO; GO:0006351; P:DNA-templated transcription; IEA:InterPro.
DR CDD; cd02584; RNAP_II_Rpb1_C; 1.
DR Gene3D; 3.30.1360.140; -; 1.
DR Gene3D; 6.10.250.2940; -; 1.
DR Gene3D; 6.20.50.80; -; 1.
DR InterPro; IPR045867; DNA-dir_RpoC_beta_prime.
DR InterPro; IPR007081; RNA_pol_Rpb1_5.
DR InterPro; IPR007075; RNA_pol_Rpb1_6.
DR InterPro; IPR007073; RNA_pol_Rpb1_7.
DR InterPro; IPR038593; RNA_pol_Rpb1_7_sf.
DR PANTHER; PTHR19376; DNA-DIRECTED RNA POLYMERASE; 1.
DR PANTHER; PTHR19376:SF37; DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB1; 1.
DR Pfam; PF04998; RNA_pol_Rpb1_5; 1.
DR Pfam; PF04992; RNA_pol_Rpb1_6; 1.
DR Pfam; PF04990; RNA_pol_Rpb1_7; 1.
DR SUPFAM; SSF64484; beta and beta-prime subunits of DNA dependent RNA-polymerase; 1.
PE 4: Predicted;
KW DNA-directed RNA polymerase {ECO:0000256|ARBA:ARBA00022478};
KW Nucleotidyltransferase {ECO:0000256|ARBA:ARBA00022695};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 25..606
FT /note="RNA polymerase Rpb1"
FT /evidence="ECO:0000259|Pfam:PF04998"
FT DOMAIN 91..274
FT /note="RNA polymerase Rpb1"
FT /evidence="ECO:0000259|Pfam:PF04992"
FT DOMAIN 359..493
FT /note="RNA polymerase Rpb1"
FT /evidence="ECO:0000259|Pfam:PF04990"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:ABV83178.1"
FT NON_TER 614
FT /evidence="ECO:0000313|EMBL:ABV83178.1"
SQ SEQUENCE 614 AA; 69282 MW; ECCF02CC547560E8 CRC64;
TLPHFIKDDY GPESRGFVEN SYLAGLTPAE FFFHAMGGRE GLIDTAVKTA ETGYIQRRLI
KAMESVMVNY DGTVXNSIGQ XXQLRYGEDG LDGTWVENQX XPTMKPNDAL FEKEFKLDLG
DDRLLRRIYT EDVIRSLQSS AVSLNEVEEE WKQLVKDRRT LREIFPKGDA KVVLPCNVQR
LIWNAQKIFH VEIRRPVSLS PLRVIEGVRE LTARLVIVSG EDHISQHAQE NATLLIKILL
RSTLCSRKMA EQHRLNAEAF EWLLGEVXTR FQQAXXXXXX XXXALAAQSL GEPATQMTLN
TFHYAGVSAK NVTLGVPRLK EIINVSKQPK TPSLTVFLRG AAAKDAEKAK DVLCRLEHTT
LRKVTANTAI YYDPDPVNTQ IAEDAEWVSI FYEMPDVDHA RVSPWLLRIE LDRKRMTDKK
LTMDAVADCI RRGFGDDLNI VYTDDNAEKL VIRIRIANSD AEKGATEEQV DKMEDDGFLR
CIEANMLSEL TLQGIESITK VYMHKPTTDD KKRMVITPEG GFKAVAEWLL ETDGTALLKV
LSDRDVDPVR TTSNDICEIF AVLGIEAVRK AIEREMHQVI SFDGSYVNYR HLALLCDVMT
AKGHLWRSLG TAST
//
