ID A9UMK5_XENTR Unreviewed; 306 AA.
AC A9UMK5; F6TDW1;
DT 05-FEB-2008, integrated into UniProtKB/TrEMBL.
DT 05-FEB-2008, sequence version 1.
DT 27-MAR-2024, entry version 67.
DE SubName: Full=LOC100135382 protein {ECO:0000313|EMBL:AAI57693.1};
DE SubName: Full=Provisional ortholog of phospholipid phosphatase 3 {ECO:0000313|Ensembl:ENSXETP00000031941};
GN Name=XB5961369 {ECO:0000313|Xenbase:XB-GENE-5961370};
GN Synonyms=LOC100135382 {ECO:0000313|EMBL:AAI57693.1,
GN ECO:0000313|RefSeq:NP_001107520.1}, XB5961369 [provisional:plpp3]
GN {ECO:0000313|Ensembl:ENSXETP00000031941,
GN ECO:0000313|Xenbase:XB-GENE-5961370};
OS Xenopus tropicalis (Western clawed frog) (Silurana tropicalis).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana.
OX NCBI_TaxID=8364 {ECO:0000313|EMBL:AAI57693.1};
RN [1] {ECO:0000313|RefSeq:NP_001107520.1}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=12454917; DOI=10.1002/dvdy.10174;
RA Klein S.L., Strausberg R.L., Wagner L., Pontius J., Clifton S.W.,
RA Richardson P.;
RT "Genetic and genomic tools for Xenopus research: The NIH Xenopus
RT initiative.";
RL Dev. Dyn. 225:384-391(2002).
RN [2] {ECO:0000313|EMBL:AAI57693.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=N6 {ECO:0000313|EMBL:AAI57693.1};
RC TISSUE=Lung {ECO:0000313|EMBL:AAI57693.1};
RG NIH - Xenopus Gene Collection (XGC) project;
RL Submitted (DEC-2007) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|Ensembl:ENSXETP00000031941}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Nigerian {ECO:0000313|Ensembl:ENSXETP00000031941};
RX PubMed=20431018; DOI=10.1126/science.1183670;
RA Hellsten U., Harland R.M., Gilchrist M.J., Hendrix D., Jurka J.,
RA Kapitonov V., Ovcharenko I., Putnam N.H., Shu S., Taher L., Blitz I.L.,
RA Blumberg B., Dichmann D.S., Dubchak I., Amaya E., Detter J.C., Fletcher R.,
RA Gerhard D.S., Goodstein D., Graves T., Grigoriev I.V., Grimwood J.,
RA Kawashima T., Lindquist E., Lucas S.M., Mead P.E., Mitros T., Ogino H.,
RA Ohta Y., Poliakov A.V., Pollet N., Robert J., Salamov A., Sater A.K.,
RA Schmutz J., Terry A., Vize P.D., Warren W.C., Wells D., Wills A.,
RA Wilson R.K., Zimmerman L.B., Zorn A.M., Grainger R., Grammer T.,
RA Khokha M.K., Richardson P.M., Rokhsar D.S.;
RT "The genome of the Western clawed frog Xenopus tropicalis.";
RL Science 328:633-636(2010).
RN [4] {ECO:0000313|Ensembl:ENSXETP00000031941}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (JUN-2011) to UniProtKB.
RN [5] {ECO:0000313|RefSeq:NP_001107520.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the PA-phosphatase related phosphoesterase
CC family. {ECO:0000256|ARBA:ARBA00008816}.
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DR EMBL; BC157692; AAI57693.1; -; mRNA.
DR RefSeq; NP_001107520.1; NM_001114048.1.
DR Ensembl; ENSXETT00000031941; ENSXETP00000031941; ENSXETG00000017268.
DR GeneID; 100135382; -.
DR KEGG; xtr:100135382; -.
DR AGR; Xenbase:XB-GENE-5961370; -.
DR CTD; 100135382; -.
DR Xenbase; XB-GENE-5961370; XB5961369.
DR eggNOG; KOG3030; Eukaryota.
DR HOGENOM; CLU_021458_3_1_1; -.
DR OMA; FKPCTRP; -.
DR OrthoDB; 25293at2759; -.
DR TreeFam; TF316040; -.
DR Proteomes; UP000008143; Chromosome 3.
DR Bgee; ENSXETG00000017268; Expressed in mesonephros and 10 other cell types or tissues.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0006644; P:phospholipid metabolic process; IEA:InterPro.
DR CDD; cd03384; PAP2_wunen; 1.
DR Gene3D; 1.20.144.10; Phosphatidic acid phosphatase type 2/haloperoxidase; 1.
DR InterPro; IPR036938; P_Acid_Pase_2/haloperoxi_sf.
DR InterPro; IPR000326; P_Acid_Pase_2/haloperoxidase.
DR InterPro; IPR043216; PA_PP_rel.
DR PANTHER; PTHR10165; LIPID PHOSPHATE PHOSPHATASE; 1.
DR PANTHER; PTHR10165:SF94; PHOSPHATIDIC ACID PHOSPHATASE TYPE 2D; 1.
DR Pfam; PF01569; PAP2; 1.
DR SMART; SM00014; acidPPc; 1.
DR SUPFAM; SSF48317; Acid phosphatase/Vanadium-dependent haloperoxidase; 1.
PE 2: Evidence at transcript level;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000008143};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 42..69
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 89..109
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 129..150
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 200..218
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 230..249
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 261..279
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 137..276
FT /note="Phosphatidic acid phosphatase type 2/haloperoxidase"
FT /evidence="ECO:0000259|SMART:SM00014"
SQ SEQUENCE 306 AA; 34091 MW; BFABBE4D5B518B7C CRC64;
MHLTPGGAPD WCPDPRVLKV TVGGHCVQKE TRSPVSRGSR RYLICLDLLC LCIVSIPFLI
CELGVVAPIH RGFFCDDTTI QFPVIHQETI SDTVLISVGI LITGVTIALG ECYRVSRQNN
SKSRPRESYL AAVYCQLLPF LFGSALGQSI TNAAKLSAGR LRPNFLSVCQ PEGLNCTTGF
IETYRCTGDA GAVTEARKSF YSGHASFSMY SMLYLTFYLQ VRLTWRGARL LRPLVQFVLI
LVSLYTGFTR ISDYRHHPSD VVVGFLQGAL VAYWVAFHIS DLFRKKKSEY VTVPPRPESP
ETFTNC
//
